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ChemicalBook >> CAS DataBase List >>(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Structure
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide structure
CAS No.
1175838-84-2
Chemical Name:
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide
Synonyms
Bima SA;Bimatoprost serinol amide;17-phenyl trinor Prostaglandin F2α serinol amide;N-[(2-hydroxy-1-hydroxymethyl)ethyl]-9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide;5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-, (5Z)-
CBNumber:
CB13903897
Molecular Formula:
C26H39NO6
Molecular Weight:
461.59
MDL Number:
MFCD08062131
MOL File:
1175838-84-2.mol
MSDS File:
SDS
Last updated:2026-05-27 23:34:01
Request For Quotation

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Properties

Boiling point 737.3±60.0 °C(Predicted)
Density 1.231±0.06 g/cm3(Predicted)
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH7.2): .5 mg/ml
pka 13.97±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10004237 17-phenyl trinor Prostaglandin F2α serinol amide ≥98% 1175838-84-2 1mg $81 2026-04-30 Buy
Cayman Chemical 10004237 17-phenyl trinor Prostaglandin F2α serinol amide ≥98% 1175838-84-2 5mg $357 2026-04-30 Buy
Cayman Chemical 10004237 17-phenyl trinor Prostaglandin F2α serinol amide ≥98% 1175838-84-2 10mg $633 2026-04-30 Buy
Cayman Chemical 10004237 17-phenyl trinor Prostaglandin F2α serinol amide ≥98% 1175838-84-2 50mg $2756 2026-04-30 Buy
Biosynth AXB83884 17-Phenyl trinor prostaglandin f2α serinol amide 1175838-84-2 10mg $853.8 2026-06-04 Buy
Product number Packaging Price Buy
10004237 1mg $81 Buy
10004237 5mg $357 Buy
10004237 10mg $633 Buy
10004237 50mg $2756 Buy
AXB83884 10mg $853.8 Buy

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Chemical Properties, Uses, Production

Description

2-Arachidonyl glycerol (2-AG) exhibits cannabinoid agonist activity at the central cannabinoid (CB1) receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor1,2. 2-AG can also be metabolized by COX-2 to form prostaglandin (PG) 2-glyceryl esters.3 These 2-glyceryl esters rapidly equilibrate to form 90:10 mixtures favoring the more stable 1-glyceryl ester. 17-phenyl trinor PGF2α serinol amide is a stable analog of PGF2α 2-glyceryl ester incorporating an activity-enhancing 17-phenyl substitution. The biological activity of 17-phenyl trinor PGF2α serinol amide has not yet been determined.

Uses

Bima SA (Bimatoprost serinol amide) is a Prostaglandin analog and has the potential for the research of glaucoma[1].

References

1. Sugiura, T., Kodaka, T., Kondo, S., et al. Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor Structural requirements for triggering a Ca2+ transient in NG108-15 cells J. Biochem. 122(4),890-895(1997).
2. Kondo, S., Kondo, H., Nakane, S., et al. 2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: Identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through Ca2+-dependent and -independent mechanisms FEBS Lett. 429(2),152-156(1998).
3. Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides J. Biol. Chem. 277(47),44877-44885(2002).

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Preparation Products And Raw materials

Raw materials

Preparation Products

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Suppliers

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25030 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Universal Biotech Co.,Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

1175838-84-2 ((Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide) Related Search:

17-phenyl trinor Prostaglandin F2α diethyl amide BiMatoprost IMpurity III 17- Phenyl Trinor Prostaglandin F2α Methyl Amide 17-Phenyl trinor prostaglandin f2alpha amide 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide
15-Keto prostaglandin E2

1of2

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Bimatoprost serinol amide 17-phenyl trinor Prostaglandin F2α serinol amide 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-, (5Z)- N-[(2-hydroxy-1-hydroxymethyl)ethyl]-9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide Bima SA 1175838-84-2