5-Cyano-2,3-dihydro-1H-indole
- CAS No.
- 15861-23-1
- Chemical Name:
- 5-Cyano-2,3-dihydro-1H-indole
- Synonyms
- 5-Cyanoindoline;5-Indolinecarbonitrile;Indoline-5-carbonitrile ,97%;5-Cyano-2,3-dihydro-1H-indole;Indoline-5-carbonitrile - [K72445];2,3-dihydro-1H-indole-5-carbonitrile;1H-Indole-5-carbonitrile, 2,3-dihydro-;5-Cyanoindoline 5-CYANO-2,3-DIHYDRO-1H-INDOLE in stock Factory
- CBNumber:
- CB1399079
- Molecular Formula:
- C9H8N2
- Molecular Weight:
- 144.17
- MDL Number:
- MFCD07371626
- MOL File:
- 15861-23-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312+P330-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| Safety Statements | 24/25 |
| HS Code | 29339900 |
5-Cyano-2,3-dihydro-1H-indole price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-C955825-50MG | 5-Cyano-2,3-dihydro-1H-indole | 15861-23-1 | 50mg | $65 | 2026-06-03 | Buy |
| Apolloscientific | OR953724 | 5-Cyano-2,3-dihydro-1H-indole 97% | 15861-23-1 | 100mg | $37 | 2026-06-04 | Buy |
| Apolloscientific | OR953724 | 5-Cyano-2,3-dihydro-1H-indole 97% | 15861-23-1 | 250mg | $47 | 2026-06-04 | Buy |
| Apolloscientific | OR953724 | 5-Cyano-2,3-dihydro-1H-indole 97% | 15861-23-1 | 1g | $115 | 2026-06-04 | Buy |
| Apolloscientific | OR953724 | 5-Cyano-2,3-dihydro-1H-indole 97% | 15861-23-1 | 5g | $400 | 2026-06-04 | Buy |
5-Cyano-2,3-dihydro-1H-indole Chemical Properties, Uses, Production
Chemical Properties
Light pink solid
Synthesis
15861-24-2
15861-23-1
General procedure for the synthesis of 5-indolinecarbonitrile from 5-cyanoindole: 5-cyanoindole (1 g, 7 mmol) was dissolved in 10 mL of trifluoroacetic acid (TFA) and the solution was cooled to 0 °C. Subsequently, triethylsilane (1.6 g, 14 mmol, 2 equiv) was added to the solution. The reaction mixture was kept stirred at 0 °C for 4 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (EtOAc) and washed with 1 M hydrochloric acid (HCl) solution. The aqueous layers were combined, neutralized to pH 10 with 50% sodium hydroxide (NaOH) solution and then extracted three times with ethyl acetate. The organic extracts were combined, washed with saturated brine, dried over anhydrous sodium sulfate and the solvent was evaporated under reduced pressure to give the target product 5-indolinecarbonitrile in 77% yield.
References
[1] Patent: US2004/220206, 2004, A1. Location in patent: Page 25-26
[2] Journal of Materials Chemistry A, 2015, vol. 3, # 34, p. 17704 - 17712
[3] Patent: CN105085504, 2018, B. Location in patent: Paragraph 0139; 0147-0150
[4] Patent: WO2014/188173, 2014, A1. Location in patent: Paragraph 00239; 00521
[5] Patent: US2004/220206, 2004, A1. Location in patent: Page 25
5-Cyano-2,3-dihydro-1H-indole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Carbott PharmTech Inc. | 0535-6385396 | info@carbottpharm.com | China | 995 | 56 |
| Accela ChemBio Co.,Ltd. | 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Shanghai Xiannuo Biotechnology Co., Ltd. | 021-50718719 13918719472 | China | 978 | 58 | |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Chemwill Asia Co.,Ltd. | 86-21-51086038 | China | 2928 | 58 | |
| Shanghai ChuangYan Chemical Technology Co., Ltd. | 021-11111111 11111111111 | 546919421@qq.com | China | 3789 | 55 |
View Latest Price from 5-Cyano-2,3-dihydro-1H-indole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-06-02 | 5-Cyanoindoline 5-CYANO-2,3-DIHYDRO-1H-INDOLE in stock Factory
15861-23-1
|
$1.00 | 1KG | TOP 3 Factory in China | Chemwill Asia Co.,Ltd. | ||
 |
2019-07-06 | 5-CYANO-2,3-DIHYDRO-1H-INDOLE
15861-23-1
|
$8.00 | 1kg | 99% | 10tons | Career Henan Chemical Co |
-
- 5-Cyanoindoline 5-CYANO-2,3-DIHYDRO-1H-INDOLE in stock Factory
15861-23-1
- $1.00
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- 5-CYANO-2,3-DIHYDRO-1H-INDOLE
15861-23-1
- $8.00
- 99%
- Career Henan Chemical Co
