4-Acetamidopiperidine
- CAS No.
- 5810-56-0
- Chemical Name:
- 4-Acetamidopiperidine
- Synonyms
- 4-Acetamidopiperidine;4-Acetylamino-piperidine;4-Acetamidopiperidine >N-PIPERIDIN-4-YL-ACETAMIDE;Acetamide, N-4-piperidinyl-;N-piperidine-4-yl-acetamide;4-(N-Ethanoylamino)piperidine;4-ACETYLAMINO-PIPERIDINE >98%;N-(4-Piperidinyl)acetamide
- CBNumber:
- CB1407855
- Molecular Formula:
- C7H14N2O
- Molecular Weight:
- 142.2
- MDL Number:
- MFCD05254805
- MOL File:
- 5810-56-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 141 °C |
|---|---|
| Boiling point | 318.5±31.0 °C(Predicted) |
| Density | 1.02 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | soluble in Methanol |
| pka | 15.96±0.20(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| InChI | 1S/C7H14N2O/c1-6(10)9-7-2-4-8-5-3-7/h7-8H,2-5H2,1H3,(H,9,10) |
| InChIKey | YLWUSMHZABTZGP-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1CCNCC1 |
| CAS DataBase Reference | 5810-56-0(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 36/37/39-37-26 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
4-Acetamidopiperidine price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS000127 | N-(4-Piperidinyl)acetamide AldrichCPR | 5810-56-0 | 100mg | $68.1 | 2023-06-20 | Buy |
| TCI Chemical | A1653 | 4-Acetamidopiperidine >98.0%(GC)(T) | 5810-56-0 | 5g | $89 | 2026-04-30 | Buy |
| TCI Chemical | A1653 | 4-Acetamidopiperidine >98.0%(GC)(T) | 5810-56-0 | 25g | $266 | 2026-04-30 | Buy |
| AstaTech | 50436 | 4-ACETAMIDOPIPERIDINE 97% | 5810-56-0 | 1G | $27 | 2026-04-30 | Buy |
| AstaTech | 50436 | 4-ACETAMIDOPIPERIDINE 97% | 5810-56-0 | 5G | $59 | 2026-04-30 | Buy |
4-Acetamidopiperidine Chemical Properties, Uses, Production
Synthesis
50534-23-1
5810-56-0
General procedure for the synthesis of 4-acetamido-piperidine from 4-acetamido-1-benzylpiperidine: preparation of intermediate 40: N-piperidin-4-yl-acetamide (method step 10). Pd-C (350 mg) was added to a solution of N-(1-benzyl-piperidin-4-yl)-acetamide (intermediate 39) (2.3 g, 10.0 mmol) in EtOH (35 mL) and HCl (1 M, 5 mL), and the mixture was stirred for 5 hr under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through diatomaceous earth followed by washing with EtOH and then water. The filtrate was concentrated under vacuum and the product was purified by column chromatography using a methanol solution of dichloromethane/7M NH3 (100:0 to 80:20) as eluent to give the intermediate 40 (0.92 g, 65% yield). Since the compound could not be detected by HPLC-MS, its structure was confirmed by NMR.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 14, p. 2303 - 2306
[2] Organic Process Research and Development, 2012, vol. 16, # 3, p. 470 - 483
[3] Patent: US2012/214798, 2012, A1
[4] Patent: US2005/43298, 2005, A1. Location in patent: Page/Page column 35
[5] Patent: US2005/197333, 2005, A1. Location in patent: Page/Page column 39-40
4-Acetamidopiperidine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 45000 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Lavem Chine Pharm Company | 028-62070218 18190869852 | sales@lavemc.com | China | 214 | 67 |
| Chengdu HappySyn Pharmaceutical Technology Co., Ltd. | 85114309 18982182443 | yangli@happysyn.com | China | 2334 | 55 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
View Latest Price from 4-Acetamidopiperidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 4-ACETAMIDOPIPERIDINE
5810-56-0
|
$1.00 | 1kg | 95%-99% | Career Henan Chemical Co |
-
- 4-ACETAMIDOPIPERIDINE
5810-56-0
- $1.00
- 95%-99%
- Career Henan Chemical Co
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