1-(Phenylsulfonyl)-1H-indole-3-carbaldehyde
- CAS No.
- 80360-20-9
- Chemical Name:
- 1-(Phenylsulfonyl)-1H-indole-3-carbaldehyde
- Synonyms
- NSC 628191;BUTTPARK 98 4-06;BUTTPARK 98\04-06;1-(Phenylsulfonyl)-3-formylindole;3-Formyl-1-(phenylsulphonyl)-1H-indole;1-(Phenylsulfonyl)indole-3-carbaldehyde;1-PHENYLSULPHONYLINDOLE-3-CARBOXALDEHYDE;1-(PHENYLSULFONYL)-3-INDOLECARBOXALDEHY&;1-(PHENYLSULFONYL)-3-INDOLECARBOXALDEHYDE;1-(Benzenesulfonyl)indole-3-carboxaldehyde
- CBNumber:
- CB1422285
- Molecular Formula:
- C15H11NO3S
- Molecular Weight:
- 285.32
- MDL Number:
- MFCD02681985
- MOL File:
- 80360-20-9.mol
- TDS File:
- TDS
| Melting point | 157-161 °C(lit.) |
|---|---|
| Boiling point | 513.6±42.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| Appearance | Light yellow to brown Solid |
| CAS DataBase Reference | 80360-20-9 |
1-(Phenylsulfonyl)-1H-indole-3-carbaldehyde price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR23044 | 1-(Phenylsulphonyl)-1H-indole-3-carboxaldehyde >98% | 80360-20-9 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR23044 | 1-(Phenylsulphonyl)-1H-indole-3-carboxaldehyde >98% | 80360-20-9 | 250mg | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR23044 | 1-(Phenylsulphonyl)-1H-indole-3-carboxaldehyde >98% | 80360-20-9 | 1g | $74 | 2026-06-04 | Buy |
| Apolloscientific | OR23044 | 1-(Phenylsulphonyl)-1H-indole-3-carboxaldehyde >98% | 80360-20-9 | 5g | $224 | 2026-06-04 | Buy |
| Apolloscientific | OR23044 | 1-(Phenylsulphonyl)-1H-indole-3-carboxaldehyde >98% | 80360-20-9 | 25g | $759 | 2026-06-04 | Buy |
1-(Phenylsulfonyl)-1H-indole-3-carbaldehyde Chemical Properties,Uses,Production
Synthesis
487-89-8
98-09-9
80360-20-9
GENERAL STEPS: NaH (60% dispersed in mineral oil, 40.00 mmol, 0.96 g) was added in batches to a stirred solution of 3-indolecarboxaldehyde (20.00 mmol, 2.90 g) in anhydrous THF (50 mL) under ice bath cooling conditions. After slowly warming to room temperature, stirring was continued for 30 min. Subsequently, anhydrous THF solution of benzenesulfonyl chloride (24.00 mmol, 4.24 g) was added dropwise. The progress of the reaction was monitored by TLC and after complete disappearance of the raw material 3-indolecarboxaldehyde, the solvent was removed by evaporation under reduced pressure. The reaction mixture was diluted with ice water (300 mL) and the solid product was collected by filtration. Recrystallization with acetone/petroleum ether (60-90 °C) afforded the target product 1-(phenylsulfonyl)-3-indolecarboxaldehyde in 97% yield, melting point 151-153 °C. 1H NMR (600 MHz, CDCl3): δ 7.37 (t, J = 7.2 Hz, 1H), 7.42 (dd, J = 11.4, 4.2 Hz, 1H), 7.52 (t, J = 7.8 Hz, 2H), 7.62 (t, J = 7.2 Hz, 1H), 7.97 (t, J = 7.8 Hz, 3H), 8.20-8.31 (m, 2H), 10.11 (s, 1H). HRMS (MALDI): m/z 286.0515. calculated value C15H11NO3S: [M + H]+ 286.0538.
References
[1] Synlett, 1999, # 6, p. 786 - 788
[2] European Journal of Medicinal Chemistry, 2012, vol. 53, p. 283 - 291
[3] Journal of Organic Chemistry, 2002, vol. 67, # 3, p. 1001 - 1003
[4] Synthetic Communications, 2007, vol. 37, # 5, p. 829 - 837
[5] Tetrahedron, 1998, vol. 54, # 46, p. 13915 - 13928
1-(Phenylsulfonyl)-1H-indole-3-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
1-(Phenylsulfonyl)-1H-indole-3-carbaldehyde Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4905 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Beijing FYF Chemicals Co., Ltd | 010-57903446 15869909019 | 168931144@qq.com | China | 2876 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
80360-20-9(1-(Phenylsulfonyl)-1H-indole-3-carbaldehyde)Related Search:
1of4
