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ChemicalBook >> CAS DataBase List >>(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone

(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone

(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone Structure
(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone structure
CAS No.
1040706-91-9
Chemical Name:
(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone
Synonyms
NPD10084;(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone;Methanone, (4-methoxy-1H-indol-2-yl)(1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-
CBNumber:
CB14286339
Molecular Formula:
C21H19N3O2
Molecular Weight:
345.39
MDL Number:
MFCD12029753
MOL File:
1040706-91-9.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:42
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(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone Properties

Boiling point 640.1±55.0 °C(Predicted)
Density 1.364±0.06 g/cm3(Predicted)
form Solid
pka 15.92±0.30(Predicted)
color Off-white to light yellow

(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0645824 NPD10084 99.69% 1040706-91-9 5mg $108 2026-06-04 Buy
ChemScene CS-0645824 NPD10084 99.69% 1040706-91-9 10mg $173 2026-06-04 Buy
ChemScene CS-0645824 NPD10084 99.69% 1040706-91-9 25mg $379 2026-06-04 Buy
ChemScene CS-0645824 NPD10084 99.69% 1040706-91-9 50mg $596 2026-06-04 Buy
ChemScene CS-0645824 NPD10084 99.69% 1040706-91-9 100mg $921 2026-06-04 Buy
Product number Packaging Price Buy
CS-0645824 5mg $108 Buy
CS-0645824 10mg $173 Buy
CS-0645824 25mg $379 Buy
CS-0645824 50mg $596 Buy
CS-0645824 100mg $921 Buy

(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone Chemical Properties, Uses, Production

Uses

NPD10084 is a pyruvate kinase PKM2 inhibitor that inhibits non-glycolytic signaling in cancer cells. NPD10084 disrupts the interaction between PKM2 and β-catenin or STAT3 and inhibits downstream signaling. NPD10084 has antiproliferative activity against colorectal cancer cells in vitro and in vivo[1].

References

[1] Nagasawa I, et al. Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA. Cell Chem Biol. 2020 Feb 20;27(2):186-196.e4. DOI:10.1016/j.chembiol.2019.11.010

(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone Preparation Products And Raw materials

Raw materials

Preparation Products

(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone Suppliers

Global Suppliers ( 12)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988941452 YN_research@163.com China 2984 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4999 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 024-88590548 18698872706 757984502@qq.com China 960 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd +86-18341751992 +86-15382112998 757984502@qq.com China 890 58
Supplier Advantage
BOC Sciences 65
Shanghai Beckham Medical Technology Co., Ltd 55
Shanghai EFE Biological Technology Co., Ltd. 58
Guangzhou Younan Technology Co., Ltd 58
ShangHai ChuanQian Chemcial Technique Centre 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 58
TargetMol Chemicals Inc. 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 58

1040706-91-9 ((4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone) Related Search:

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(4-methoxy-1H-indol-2-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone NPD10084 Methanone, (4-methoxy-1H-indol-2-yl)(1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)- 1040706-91-9