BETA-NAADP SODIUM SALT
- CAS No.
- 5502-96-5
- Chemical Name:
- BETA-NAADP SODIUM SALT
- Synonyms
- NAADP;NAADP tetrasodium sa;NAADP tetrasodium salt;BETA-NAADP SODIUM SALT;Coenzyme A Impurity 15;NICOTINATE ADENINE DINUCLEOTIDE PHOSPHATE;Nicotinic acid adenine dinucleotide phosphate;nicotinic acid adenine dinucleotide*phosphate sod;NAADP (NICOTINATE ADENINE DINUCLEOTIDE P HOSPHATE);BETA-NICOTINIC ACID ADENINE DINUCLEOTIDE PHOSPHATE
- CBNumber:
- CB1459162
- Molecular Formula:
- C21H28N7O17P3
- Molecular Weight:
- 743.41
- MDL Number:
- MFCD00274064
- MOL File:
- 5502-96-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | -20°C |
|---|---|
| form | Powder |
| color | White to off-white |
| Water Solubility | Soluble to 50 mM in water |
| Cosmetics Ingredients Functions |
SKIN PROTECTING SKIN CONDITIONING |
| InChIKey | KKCRODBDXQTAPI-NZNNTXIPSA-M |
| SMILES | [Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OCC4O[C@@H]([C@@H](O)[C@H]4O)[n+]5cccc(c5)C(O)=O)[C@@H](O)[C@H]3OP(O)(O)=O |
| UNSPSC Code | 12352106 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
BETA-NAADP SODIUM SALT price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N5655 | Nicotinic acid adenine dinucleotide phosphate sodium salt ≥92.5% | 5502-96-5 | 10mg | $512 | 2026-04-30 | Buy |
| Sigma-Aldrich | N5655 | Nicotinic acid adenine dinucleotide phosphate sodium salt ≥92.5% | 5502-96-5 | 25mg | $1070 | 2026-04-30 | Buy |
| ChemScene | CS-0027608 | NAADP | 5502-96-5 | 1mg | $271 | 2026-06-04 | Buy |
| ChemScene | CS-0027608 | NAADP | 5502-96-5 | 5mg | $693 | 2026-06-04 | Buy |
| Chem-Impex | 42113 | Nicotinic acid adenine dinucleotide phosphate sodium salt ≥92.5% | 5502-96-5 | 10MG | $465.8 | 2026-05-19 | Buy |
BETA-NAADP SODIUM SALT Chemical Properties, Uses, Production
Uses
NAADP Tetrasodium Salt is a Ca2+ mobilizing agent.
Uses
Nicotinic acid adenine dinucleotide phosphate sodium salt has been used for agonist injection into unfertilized eggs and embryos.
General Description
NAADP induces Ca2+release from the eggs of sea urchin, when injected into the cell. It can be enzymatically produced from nicotinamide adenine dinucleotide phosphate (β-NADP) with the help of ADP-ribosyl cyclase.
Biological Activity
Ca 2+ mobilizing agent. Initiates Ca 2+ release via type 1 ryanodine receptor (RyR1) activation. Also regulates Ca 2+ release from intracellular stores distinct from the endoplasmic reticulum (ER); displays affinity for two-pore channels (TPCs) which release Ca 2+ from acidic organelles.
Biochem/physiol Actions
Potent activator of intracellular Ca2+ release via an IP3 and cyclic ADP ribose-independent mechanism.
in vivo
NAADP (0.181 mg/kg, i.v.) promotes autophagosome formation and protects the hepatocytes from injury in mice induced by LPS/GalN[3].
| Animal Model: | LPS/GalN induced liver injury mice model[3] |
| Dosage: | 0.181 mg/kg |
| Administration: | i.v. |
| Result: | Promoted autophagosome formation in in hepatocytes. Showed higher levels of LC3II, p62, ATG5, and ATG7 in hepatocytes. |
BETA-NAADP SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
BETA-NAADP SODIUM SALT Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9883 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Hubei Yangxin Medical Technology Co., Ltd. | 15374522761 | 3003392093@yongstandards.com | China | 9995 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
