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DB2313 (DB 2313)

DB2313 (DB 2313) Structure
DB2313 (DB 2313) structure
CAS No.
2170606-74-1
Chemical Name:
DB2313 (DB 2313)
Synonyms
DB2313;DB2313 （HCl）;DB2313 (DB 2313);DB2313 DB2313.4HCl;1H-Benzimidazole-6-carboximidamide, 2,2'-[(2-fluoro-1,3-phenylene)bis(methyleneoxy-4,1-phenylene)]bis[N-(1-methylethyl)-;2,2'-((((2-Fluoro-1,3-phenylene)bis(methylene))bis(oxy))bis(4,1-phenylene))bis(N-isopropyl-1H-benzo[d]imidazole-6-carboximidamide);2,2'-((((2-Fluoro-1,3-phenylene)bis(methylene))bis(oxy))bis(4,1-phenylene))bis(N-isopropyl-1H-benzo[d]imidazole-6-carboximidamide);2-[4-({2-fluoro-3-[(4-{6-[N-(propan-2-yl)carbamimidoyl]-1H-1,3-benzodiazol-2-yl}phenoxy)methyl]phenyl}methoxy)phenyl]-N-(propan-2-yl)-1H-1,3-benzodiazole-6-carboximidamide
CBNumber:
CB14844690
Molecular Formula:
C42H41FN8O2
Molecular Weight:
708.83
MDL Number:
MFCD34179477
MOL File:
2170606-74-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
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DB2313 (DB 2313) Properties

Boiling point 880.9±75.0 °C(Predicted)
Density 1.30±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 9.74±0.10(Predicted)
color Off-white to gray

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

DB2313 (DB 2313) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth VLD60674 DB2313 2170606-74-1 50mg $1075 2026-06-05 Buy
Biosynth VLD60674 DB2313 2170606-74-1 100mg $1495 2026-06-05 Buy
ChemScene CS-0087172 DB2313 99.48% 2170606-74-1 5mg $162 2026-06-04 Buy
ChemScene CS-0087172 DB2313 99.48% 2170606-74-1 10mg $271 2026-06-04 Buy
ChemScene CS-0087172 DB2313 99.48% 2170606-74-1 25mg $538 2026-06-04 Buy
Product number Packaging Price Buy
VLD60674 50mg $1075 Buy
VLD60674 100mg $1495 Buy
CS-0087172 5mg $162 Buy
CS-0087172 10mg $271 Buy
CS-0087172 25mg $538 Buy

DB2313 (DB 2313) Chemical Properties, Uses, Production

Uses

DB2313 is a potent inhibitor of transcription factor PU.1. DB2313 inhibits PU.1-dependent reporter gene transactivation with an IC50 of 5 μM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects[1].

in vivo

DB2313 (17 mg/kg; i.p.; three times per week; for 3 weeks) treatment decreases leukemia progression and results in increased survival in mice[1].

Animal Model:NSG mice bearing sublethally irradiated (2.0 Gy) and injection with PU.1 URE–/– AML cells[1]
Dosage:17 mg/kg
Administration:Intraperitoneal injection; three times per week; for 3 weeks
Result:Decreased tumor burden and resulted in increased survival.

References

[1] Iléana Antony-Debré, et al. Pharmacological inhibition of the transcription factor PU.1 in leukemia. J Clin Invest. 2017 Dec 1;127(12):4297-4313. DOI:10.1172/JCI92504
[2] Zhang S, Zhao S, Qi Y, et al. SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner. Mol Ther Nucleic Acids. 2022;27:699-717. DOI:10.1016/j.omtn.2021.12.035

DB2313 (DB 2313) Preparation Products And Raw materials

Raw materials

Preparation Products

DB2313 (DB 2313) Suppliers

Global Suppliers ( 33)
Supplier Tel Email Country ProdList Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4862 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 18916372613 yanzihan@shyuanye.com China 87240 60
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4996 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27756 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Supplier Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai SuperLan Chemcial Technique Centre 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
ShangHai ChuanQian Chemcial Technique Centre 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58

View Latest Price from DB2313 (DB 2313) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DB2313 pictures 2026-07-14 DB2313
2170606-74-1
 $46.00-178.00 99.93% 10g TargetMol Chemicals Inc.
  • DB2313 pictures
  • DB2313
    2170606-74-1
  • $46.00-178.00
  • 99.93%
  • TargetMol Chemicals Inc.

DB2313 (DB 2313) Spectrum

DB2313 (DB 2313)(2170606-74-1)1HNMR

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DB2313 (DB 2313) DB2313 DB2313 （HCl） 1H-Benzimidazole-6-carboximidamide, 2,2'-[(2-fluoro-1,3-phenylene)bis(methyleneoxy-4,1-phenylene)]bis[N-(1-methylethyl)- 2,2'-((((2-Fluoro-1,3-phenylene)bis(methylene))bis(oxy))bis(4,1-phenylene))bis(N-isopropyl-1H-benzo[d]imidazole-6-carboximidamide) 2-[4-({2-fluoro-3-[(4-{6-[N-(propan-2-yl)carbamimidoyl]-1H-1,3-benzodiazol-2-yl}phenoxy)methyl]phenyl}methoxy)phenyl]-N-(propan-2-yl)-1H-1,3-benzodiazole-6-carboximidamide DB2313 DB2313.4HCl 2,2'-((((2-Fluoro-1,3-phenylene)bis(methylene))bis(oxy))bis(4,1-phenylene))bis(N-isopropyl-1H-benzo[d]imidazole-6-carboximidamide) 2170606-74-1 C42H41FN8O2