CP-461 free base
- CAS No.
- 227619-92-3
- Chemical Name:
- CP-461 free base
- Synonyms
- CEL031;UNII-824ZMS3BGL;CP-461 free base;CP461 free base,CP 461 free base;1H-Indene-3-acetamide, 5-fluoro-2-methyl-N-(phenylmethyl)-1-(4-pyridinylmethylene)-, (1Z)-
- CBNumber:
- CB14919877
- Molecular Formula:
- C25H21FN2O
- Molecular Weight:
- 384.45
- MDL Number:
- MOL File:
- 227619-92-3.mol
- MSDS File:
- SDS
| FDA UNII | 824ZMS3BGL |
|---|
CP-461 free base Chemical Properties, Uses, Production
Uses
CP 461 free base (OSI-461 free base) is a novel pro-apoptotic compound with the activity of inhibiting cyclic guanosine monophosphate phosphodiesterase. CP 461 free base exhibits growth inhibitory activity against a variety of human tumor cell lines in vitro. CP 461 free base selectively induces apoptosis in cancer cell lines but has no effect on normal cells. CP 461 free base can be used in the study of renal cell carcinoma, prostate cancer and Crohn's disease[1].
References
[1] Phase I and pharmacokinetic trial of the proapoptotic sulindac analog CP-461 in patients with advanced cancer PMID:12374677
CP-461 free base Preparation Products And Raw materials
Raw materials
Preparation Products
CP-461 free base Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q | meishipharma@126.com | China | 20027 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Latest Price from CP-461 free base manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-11 | CP-461 free base
227619-92-3
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
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- CP-461 free base
227619-92-3
- $1520.00-2500.00
- TargetMol Chemicals Inc.




