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CP-461 free base

CAS No.
227619-92-3
Chemical Name:
CP-461 free base
Synonyms
CEL031;UNII-824ZMS3BGL;CP-461 free base;CP461 free base,CP 461 free base;1H-Indene-3-acetamide, 5-fluoro-2-methyl-N-(phenylmethyl)-1-(4-pyridinylmethylene)-, (1Z)-
CBNumber:
CB14919877
Molecular Formula:
C25H21FN2O
Molecular Weight:
384.45
MDL Number:
MOL File:
227619-92-3.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51

CP-461 free base Properties

FDA UNII 824ZMS3BGL

CP-461 free base Chemical Properties, Uses, Production

Uses

CP 461 free base (OSI-461 free base) is a novel pro-apoptotic compound with the activity of inhibiting cyclic guanosine monophosphate phosphodiesterase. CP 461 free base exhibits growth inhibitory activity against a variety of human tumor cell lines in vitro. CP 461 free base selectively induces apoptosis in cancer cell lines but has no effect on normal cells. CP 461 free base can be used in the study of renal cell carcinoma, prostate cancer and Crohn's disease[1].

References

[1] Phase I and pharmacokinetic trial of the proapoptotic sulindac analog CP-461 in patients with advanced cancer PMID:12374677

CP-461 free base Preparation Products And Raw materials

Raw materials

Preparation Products

CP-461 free base Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20027 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58

View Latest Price from CP-461 free base manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CP-461 free base pictures 2026-05-11 CP-461 free base
227619-92-3
$1520.00-2500.00 10g TargetMol Chemicals Inc.
CP-461 free base 1H-Indene-3-acetamide, 5-fluoro-2-methyl-N-(phenylmethyl)-1-(4-pyridinylmethylene)-, (1Z)- CEL031 UNII-824ZMS3BGL CP461 free base,CP 461 free base 227619-92-3