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N-Demethyl erythromycin a

CAS No.
992-62-1
Chemical Name:
N-Demethyl erythromycin a
Synonyms
Erythromycin Imp B;Demethylerythromycin;N-Demethylerithromycyn;3'-Demethylerythromyon;N-Demethyl-erythromycin;Des-N-methylerythromycin;Erythromycin impurity 02;Erythromycin Impurity 16;Erythromyon, 3'-demethyl-;Erythromycin, N-demethyl-
CBNumber:
CB1501579
Molecular Formula:
C36H65NO13
Molecular Weight:
719.9
MDL Number:
MFCD09840320
MOL File:
992-62-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:49:17

N-Demethyl erythromycin a Properties

Melting point 142-144°C
Boiling point 818.1±65.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
pka 13.09±0.70(Predicted)
color White to Off-White
Major Application pharmaceutical
InChIKey TXOOBKBDBNRQCF-MBICAZOWNA-N
SMILES N(C1C(C(OC(C1)C)OC2C(CC(C(=O)C(C(C(C(OC(=O)C(C(C2C)OC3OC(C(C(C3)(OC)C)O)C)C)CC)(O)C)O)C)C)(O)C)O)C
CAS DataBase Reference 992-62-1
FDA UNII 5CUO27O3DC
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P
WGK Germany  WGK 3
HS Code  2941500000
Storage Class 11 - Combustible Solids
NFPA 704
0
2 0

N-Demethyl erythromycin a price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1242032 Erythromycin Related Compound N 992-62-1 50mg $1440 2026-04-30 Buy
Sigma-Aldrich 1134642 N-Demethylerithromycyn 992-62-1 10mg $1440 2026-04-30 Buy
Cayman Chemical 27988 N-Demethylerythromycin A ≥95% 992-62-1 500μg $63 2026-04-30 Buy
Cayman Chemical 27988 N-Demethylerythromycin A ≥95% 992-62-1 1mg $110 2026-04-30 Buy
Cayman Chemical 27988 N-Demethylerythromycin A ≥95% 992-62-1 5mg $242 2026-04-30 Buy
Product number Packaging Price Buy
1242032 50mg $1440 Buy
1134642 10mg $1440 Buy
27988 500μg $63 Buy
27988 1mg $110 Buy
27988 5mg $242 Buy

N-Demethyl erythromycin a Chemical Properties, Uses, Production

Chemical Properties

White Solid

Uses

N-Demethylerythromycin A is a minor co-metabolite of erythromycin produced by Saccharopolyspora erythreae. N-Demethylerythromycin A exhibits a very narrow spectrum of antibiotic activity and is much less active than erythromycins A, B and C.

Uses

N-Demethyl Erythromycin A (Erythromycin EP Impurity B) is a metabolite of Erythromycin (E649950).

114-07-8
992-62-1
Synthesis of N-Demethyl erythromycin a from Erythromycin

N-Demethyl erythromycin a Preparation Products And Raw materials

Global Suppliers ( 88)
Supplier Tel Email Country ProdList Advantage
Guangzhou Alice Biotechnology Co., Ltd. 0898-31318057 13265151549 3080931802@qq.com China 182 58
Jiangsu Wansipu Technology Co., Ltd. 17826022701 1485609990@qq.com China 1000 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5000 50
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9656 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60

View Latest Price from N-Demethyl erythromycin a manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Demethylerythromycin A pictures 2026-04-21 N-Demethylerythromycin A
992-62-1
$250.00-960.00 10g TargetMol Chemicals Inc.
N-DEMETHYL ERYTHROMYCIN A pictures 2019-12-26 N-DEMETHYL ERYTHROMYCIN A
992-62-1
$1.00 1g ≥98% Career Henan Chemical Co
Erythromycin EP Impurity B/N-Demethyl Erythromycin A Erythromycin Impurity 16(Erythromycin EP Impurity B) Erythromycin Impurit B:(N-demethylerythromycin A) Clarithromycin Impurity R (10 mg) (N-desmethyl erythromycin A) DeMethylerythroMycin A, N- N-Demethylerithromycyn N-Desmethyl Erythromycin A Demethylerythromycin Des-N-methylerythromycin N-Demethyl-erythromycin 3'-Demethylerythromyon Erythromyon, 3'-demethyl- Clarithromycin EP Impurity R Clarithromycin Impurity 18(Clarithromycin EP Impurity R) N-Demethylerythromycin A CRS Erythromycin, N-demethyl- Clarithromycin EP Impurity R (N-Desmethyl 6-O-Desmethyl Clarithromycin/ N-Desmethyl Erythromycin A/ Erythromycin EP Impurity B/ Erythromycin Related Compund N) Erythromycin Imp B Erythromycin EP Impurity B/ Erythromycin Related Compund N (Clarithromycin EP Impurity R/ N-Desmethyl 6-O-Desmethyl Clarithromycin/ N-Desmethyl Erythromycin A) N-Demethylerythromycin A (D0350000) Clarithromycin Impurity R (N-desmethyl erythromycin A) (1134642) Erythromycin Estolate Impurity B Erythromycin Ethylsuccinate Impurity B Erythromycin Lactobionate Impurity B Erythromycin Stearate Impurity B Erythromycin Ethylsuccinate EP Impurity B Erythromycin Lactobionate EP Impurity B Erythromycin Stearate EP Impurity B Erythromycin USP Related Compound N Erythromycin Estolate EP Impurity B Erythromycin impurity 02 (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-Ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (Erythromycin Impurity) Clarithromycin Impurity 18 2-{[4-(3-methoxypyridin-2-yl)butyl]amino}-5-[(6-methylpyridin-3-yl)methyl]pyrimidin-4(3h)-one trihydrochloride 3″-N-demethylerythromycin A 3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(methylamino)-β-D- xylohexopyranosyl]oxy]oxacyclotetradecane-2,10-dione Erythromycin impurity B, EvoPure Clarithromycin Impurity R (N-desmethyl erythromycin A) (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-dideoxy3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl6-[[3,4,6-trideoxy-3-(methylamino)-β-D-xylohexo Erythromycin Impurity B (EP) Erythromycin EP Impurity B (Erythromycin USP Related Compound N) N-Demethyl Erythromycin A (>90%) Erythromycin Impurity 16 N-Demethyl erythromycin a 992-62-1 Various Metabolites and Impurities Metabolites & Impurities