tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate
- CAS No.
- 198904-85-7
- Chemical Name:
- tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate
- Synonyms
- Atazanavir Intermediate;1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine;Atazanavir Impurity B;Atazanavir Impurity 19;1-BOC-2-PYRIDYLPHENYLMETHYL HYDRAZINE;N-1-(tert-butoxycarbonyl)-N-2-[4-(pyri;tert-Butyl4-(2-pyridyl)benzylcarbazate;phenyl]methyl]-,1,1-dimethylethyl ester;Hydrazinecarboxylic acid,2-[[4-(2-pyridinyl);Hydrazinecarboxylicacid,2-[[4-(2-pyridinyl)pheny
- CBNumber:
- CB1547452
- Molecular Formula:
- C17H21N3O2
- Molecular Weight:
- 299.37
- MDL Number:
- MFCD04035550
- MOL File:
- 198904-85-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | B59013 | 250mg | $11 |
| tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | B59013 | 1g | $56.96 |
| tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | B59013 | 5g | $60 |
| tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | B59013 | 10g | $70 |
| tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | B59013 | 25g | $100 |
| More product size | |||
| Melting point | 74-77 °C |
|---|---|
| Density | 1.117±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 10.38±0.43(Predicted) |
| form | Solid |
| color | White to Pale Yellow |
| CAS DataBase Reference | 198904-85-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | B59013 | tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | 198904-85-7 | 250mg | $11 | 2026-05-06 | Buy |
| Synthonix | B59013 | tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | 198904-85-7 | 1g | $56.96 | 2026-05-06 | Buy |
| Synthonix | B59013 | tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | 198904-85-7 | 5g | $60 | 2026-05-06 | Buy |
| Synthonix | B59013 | tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | 198904-85-7 | 10g | $70 | 2026-05-06 | Buy |
| Synthonix | B59013 | tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 97% | 198904-85-7 | 25g | $100 | 2026-05-06 | Buy |
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
An intermediate for the preparation of antiviral protease inhibitors.
Synthesis
Step 1: A mixture of 4-(pyridin-2-yl)benzaldehyde X (17.7 g, 96.6 mmol) and tert-butylcarbamate (12.2 g, 92.3 mmol) in ethanol (125 mL) was kept at reflux under nitrogen for 4 hours (h). The reaction mixture was cooled to 40 C and ice (60 g) was added. The resulting mixture was stirred for 20 minutes (min). The precipitate was collected by filtration, washed with water and dried in a vacuum oven (60 C). Product XII, yield 25.0 g, 91%.
Step 2: A solution of the above product (23.15 g, 77.85 mmol) in methanol (350 ml) was treated with 20% palladium activated charcoal (2.3 g, 50% wet) and hydrogenated at 10 psi for 4 hours. The reaction mixture was filtered through diatomaceous earth and the filter cake was washed with methanol and the solvent was removed in a rotary evaporator. The residue was recrystallized with heptane and dried in a vacuum oven (40 C). The product 2-[4-(2-pyridinyl)benzyl]-hydrazinecarboxylic acid tert-butyl ester was obtained in a yield of 2.48 g, 97%.
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 1006 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Casorganics US Corp | +17326109938 | sales@casorganics.com | CHINA | 174 | 58 |
View Lastest Price from tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-29 | tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate
198904-85-7
|
1KG | 98%min | 500kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-01-04 | 1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine
198904-85-7
|
1KG | 99% | 200 | Hangzhou ICH Biofarm Co., Ltd | ||
![]() |
2025-11-19 | tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate
198904-85-7
|
1kg | 98% | 1 Ton | Shanghai Joiny Pharmaceutical Co.,LTD |
-

- tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate
198904-85-7
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
![1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine pictures](/ProductImageEN/2023-07/Small/93560241-8565-4574-b0b2-8ef5b8c2aafe.png)
- 1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine
198904-85-7
- 99%
- Hangzhou ICH Biofarm Co., Ltd
-

- tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate
198904-85-7
- $0.00
- 98%
- Shanghai Joiny Pharmaceutical Co.,LTD





