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ChemicalBook >> CAS DataBase List >>Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester Structure
Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester structure
CAS No.
1858276-04-6
Chemical Name:
Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester
Synonyms
TAK-981;Subasumstat;Subasumstat(TAK-981);Subasumstat, 10 mM in DMSO;Subasumstat (TAK-981) ，S8829;(1R，2S，4R)-4-{[5-({4-[(1R)-7-chloro-1，2，3，4-tetrahydroisoquinolin-1-yl]-5-methyl-2-thienyl}carbonyl)pyrimidin-4-yl]amino}-2-hydroxycyclopentyl]methyl sulfamate;((1R,2S,4R)-4-((5-(4-((R)-7-Chloro-1,2,3,4-tetrahydroisoquinolin-1-yl)-5-methylthiophene-2-carbonyl)pyrimidin-4-yl)amino)-2-hydroxycyclopentyl)methyl sulfamate;(1R,2S,4R)-4-[[5-[4-[(1R)-7-Chloro-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-methylthiophene-2-carbonyl]pyrimidin-4-yl]amino]-2-hydroxycyclopentyl]methyl sulfamate;Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester;inhibit,Ubiquitin ligase,E1/E2/E3 Enzyme,Subasumstat,TAK 981,E1 activating enzyme,Ubiquitin conjugating enzyme,Inhibitor,E2 conjugating enzyme,TAK981,Ubiquitin activating enzyme,E3 ligating enzyme
CBNumber:
CB15488093
Molecular Formula:
C25H28ClN5O5S2
Molecular Weight:
578.1
MDL Number:
MFCD32062692
MOL File:
1858276-04-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
TAK-981 ≥95%(mixtureofisomers) 32741 1mg $75
TAK-981 ≥95%(mixtureofisomers) 32741 5mg $333
TAK-981 ≥95%(mixtureofisomers) 32741 10mg $516
TAK-981 ≥95%(mixtureofisomers) 32741 25mg $920
TAK-981 IZC27604 10mg $1075.9
Request For Quotation

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester Properties

Boiling point 836.1±75.0 °C(Predicted)
Density 1.474±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 16.67 mg/mL (28.84 mM; ultrasonic and warming and heat to 80°C)
form A solid
pka 9.35±0.70(Predicted)
color White to light yellow
FDA UNII XQ43H3V6M1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 32741 TAK-981 ≥95%(mixtureofisomers) 1858276-04-6 1mg $75 2026-04-30 Buy
Cayman Chemical 32741 TAK-981 ≥95%(mixtureofisomers) 1858276-04-6 5mg $333 2026-04-30 Buy
Cayman Chemical 32741 TAK-981 ≥95%(mixtureofisomers) 1858276-04-6 10mg $516 2026-04-30 Buy
Cayman Chemical 32741 TAK-981 ≥95%(mixtureofisomers) 1858276-04-6 25mg $920 2026-04-30 Buy
Biosynth IZC27604 TAK-981 1858276-04-6 10mg $1075.9 2026-06-04 Buy
Product number Packaging Price Buy
32741 1mg $75 Buy
32741 5mg $333 Buy
32741 10mg $516 Buy
32741 25mg $920 Buy
IZC27604 10mg $1075.9 Buy

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester Chemical Properties,Uses,Production

Uses

TAK-981 is a heteroaryl sulfamate compound useful as inhibitors of SUMO activating enzyme.

in vivo

A single sub-cutaneous injection of Subasumstat (TAK-981) in naive Balb/c mice at the brachial lymph nodes induces activation of DCs[2].

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32998 60
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +8619957148339 market18@leapchem.com China 24569 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38999 58
Aladdin Scientific 		tp@aladdinsci.com United States 57472 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 13636370518 shyysw007@163.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9647 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Chaolan Chemical Technology Center 58

View Lastest Price from Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Subasumstat pictures 2026-08-08 Subasumstat
1858276-04-6
 $76.00-163.00 97.05% 10g TargetMol Chemicals Inc.
  • Subasumstat pictures
  • Subasumstat
    1858276-04-6
  • $76.00-163.00
  • 97.05%
  • TargetMol Chemicals Inc.

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester Spectrum

Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester(1858276-04-6)1HNMR

1858276-04-6(Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester)Related Search:

NSC632839hydrochloride ML792 Tak-715 Pevonedistat COH000
UBA1 Protein, Human (sf9, His-GST)

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Sulfamic acid, [(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]-2-hydroxycyclopentyl]methyl ester (1R,2S,4R)-4-[[5-[4-[(1R)-7-Chloro-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-methylthiophene-2-carbonyl]pyrimidin-4-yl]amino]-2-hydroxycyclopentyl]methyl sulfamate ((1R,2S,4R)-4-((5-(4-((R)-7-Chloro-1,2,3,4-tetrahydroisoquinolin-1-yl)-5-methylthiophene-2-carbonyl)pyrimidin-4-yl)amino)-2-hydroxycyclopentyl)methyl sulfamate Subasumstat(TAK-981) inhibit,Ubiquitin ligase,E1/E2/E3 Enzyme,Subasumstat,TAK 981,E1 activating enzyme,Ubiquitin conjugating enzyme,Inhibitor,E2 conjugating enzyme,TAK981,Ubiquitin activating enzyme,E3 ligating enzyme (1R，2S，4R)-4-{[5-({4-[(1R)-7-chloro-1，2，3，4-tetrahydroisoquinolin-1-yl]-5-methyl-2-thienyl}carbonyl)pyrimidin-4-yl]amino}-2-hydroxycyclopentyl]methyl sulfamate Subasumstat, 10 mM in DMSO Subasumstat (TAK-981) ，S8829 TAK-981 Subasumstat 1858276-04-6 C25H28ClN5O5S2