VHL Antibody
- CAS No.
- Chemical Name:
- VHL Antibody
- Synonyms
- VHL Antibody;Rabbit Anti-VHL antibody;Rabbit Polyclonal VHL Antibody
- CBNumber:
- CB15704467
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| VHL Antibody | orb191988 | 50μl | $350 |
| VHL Antibody | orb191988 | 100μl | $480 |
| VHL antibody Affinity purified by Protein A | orb11544 | 100μg | $421.6 |
| VHL antibody Affinity purified by Protein A | orb11544 | 200μg | $673.2 |
VHL Antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb191988 | VHL Antibody | 50μl | $350 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb191988 | VHL Antibody | 100μl | $480 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb11544 | VHL antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb11544 | VHL antibody Affinity purified by Protein A | 200μg | $673.2 | 2021-12-16 | Buy |
VHL Antibody Chemical Properties,Uses,Production
Source
Rabbit
Applications
VHL antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.
Reactivity
Human
Immunogen
Anti-human VHL mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human VHL amino acids 1-154 purified from E. coli.
Background
Von Hippel-Lindau disease is a dominant inherited syndrome characterized by the predisposition to develop various kinds of benign and malignant tumors, including clear cell renal carcinomas, pheochromocytomas and hemangioblastomas of the central nervous system and retina. VHL syndrome is caused by germline mutation in the VHL tumor suppressor, and VHL tumors are associated with loss or mutation of the remaining wild-type allele. VHL has two domains: a roughly 100-residue NH2-terminal domain rich in sheet (-domain) and a smaller -helical domain (-domain), held together by two linkers and a polar interface. VHL protein is also involved in the degradation of hypoxia-inducible factor (HIF).
References
[1] Kibel, A. et al. (1995) Science 269, 1444-6.
[2] Pause, A. et al. (1997) Proc Natl Acad Sci U S A 94, 2156-61.
[3] Kamura, T. et al. (2000) Proc Natl Acad Sci U S A 97, 10430-5.
[4] Czyzyk-Krzeska, M.F. and Meller, J. (2004) Trends Mol Med 10, 146-9.
[5] Corn, P.G. et al. (2003) Nat Genet 35, 229-37.
[6] Na, X. et al. (2003) EMBO J 22, 4249-59.
[7] Kuznetsova, A.V. et al. (2003) Proc Natl Acad Sci U S A 100, 2706-11.
[8] Li, Z. et al. (2003) EMBO J 22, 1857-1867.
VHL Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
VHL Antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25021 | 58 |
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Hubei Serenity BioSolutions Co., Ltd. | 027-19371278702 18008634902 | 19384116026@163.com | China | 3008 | 58 |
| NSJ Bioreagents | -- | NSJBioname@qq.com | China | 6941 | 58 |
| Bio Rad Laboratories Inc | -- | Sales.China@bio-rad.com | China | 6054 | 58 |
| Enzo Biochem Inc | -- | Enzoname@qq.com | China | 6174 | 58 |
| Biosynth Ltd | -- | sales@biosynth.com | China | 6218 | 58 |
| Cell Signaling Technology Inc | -- | info@cellsignal.cn | China | 6725 | 58 |
| Abmart Inc | -- | market@ab-mart.com | China | 6917 | 58 |
| Wuhan Fine Biotech Co Ltd | -- | marketing@fn-test.com | China | 6600 | 58 |
