ChemicalBook >> CAS DataBase List >>FAK ligand-Linker Conjugate 1
FAK ligand-Linker Conjugate 1
- CAS No.
- 2307461-45-4
- Chemical Name:
- FAK ligand-Linker Conjugate 1
- Synonyms
- FAK ligand-Linker Conjugate 1;3-(2-(4-((4-((3-(N-Methylmethylsulfonamido)benzyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenoxy)ethoxy)propanoic acid;3-[2-(4-{[4-({[3-(N-methylmethanesulfonamido)phenyl]methyl}amino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenoxy)ethoxy]propanoic acid;Propanoic acid, 3-[2-[4-[[4-[[[3-[methyl(methylsulfonyl)amino]phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]phenoxy]ethoxy]-
- CBNumber:
- CB15848820
- Molecular Formula:
- C25H28F3N5O6S
- Molecular Weight:
- 583.58
- MDL Number:
- MFCD32215350
- MOL File:
- 2307461-45-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 23:39:56
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
FAK ligand-Linker Conjugate 1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | HSD46145 | Fak ligand-linker conjugate 1 | 2307461-45-4 | 5mg | $2022.05 | 2026-06-04 | Buy |
| Biosynth | HSD46145 | Fak ligand-linker conjugate 1 | 2307461-45-4 | 10mg | $3235.3 | 2026-06-04 | Buy |
| Biosynth | HSD46145 | Fak ligand-linker conjugate 1 | 2307461-45-4 | 25mg | $6066.75 | 2026-06-04 | Buy |
| Biosynth | HSD46145 | Fak ligand-linker conjugate 1 | 2307461-45-4 | 50mg | $9706.5 | 2026-06-04 | Buy |
| ChemScene | CS-0103487 | FAK ligand-Linker Conjugate 1 ≥98% | 2307461-45-4 | 1mg | $550 | 2026-06-04 | Buy |
FAK ligand-Linker Conjugate 1 Chemical Properties, Uses, Production
Uses
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation[1].
References
[1] Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026. DOI:10.1021/jacs.8b08008
FAK ligand-Linker Conjugate 1 Preparation Products And Raw materials
Raw materials
Preparation Products
FAK ligand-Linker Conjugate 1 Suppliers
Global Suppliers ( 14)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4858 | 55 | |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1644 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5123 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Suzhou Hosyn Pharm Ltd. | 17621975170; 17621975170 | sales@hosynpharm.com | China | 1735 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
2307461-45-4 (FAK ligand-Linker Conjugate 1) Related Search:
Methanesulfonamide, N-[3-[[[2-[(4-hydroxyphenyl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methyl-
2-Propynamide, N-[4-[[4-[[[2-[methyl(methylsulfonyl)amino]-3-pyridinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]phenyl]-
MS4078
1-Piperidineacetic acid, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-, 1,1-dimethylethyl ester
N-[(6S)-8-Fluoro-5,6-dihydro-4-(1-Methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-MethylMethanesulfonaMide
1of2
FAK ligand-Linker Conjugate 1
Propanoic acid, 3-[2-[4-[[4-[[[3-[methyl(methylsulfonyl)amino]phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]phenoxy]ethoxy]-
3-(2-(4-((4-((3-(N-Methylmethylsulfonamido)benzyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenoxy)ethoxy)propanoic acid
3-[2-(4-{[4-({[3-(N-methylmethanesulfonamido)phenyl]methyl}amino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenoxy)ethoxy]propanoic acid
2307461-45-4
C25H28F3N5O6S
