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Triethyl 4-phosphonocrotonate

Triethyl 4-phosphonocrotonate Structure
Triethyl 4-phosphonocrotonate structure
CAS No.
10236-14-3
Chemical Name:
Triethyl 4-phosphonocrotonate
Synonyms
Ethyl 4-(diethoxyphosphoryl);Triethyl 4-phosphonocrotonate;TRIETHYL 4-PHOSPHONO-2-BUTENOATE;triethyl trans-4-phosphono-2-butenoate;4-PHOSPHONOCROTONIC ACID TRIETHYL ESTER;Ethyl 4-(diethoxyphosphinyl)-2-butenoate;TRANS-ETHYL-4-(DIETHYLPHOSPHONO)CROTONATE;triethyl 4-phosphonocrotonate, cis + trans;(E)-Ethyl 4-(diethoxyphosphoryl)but-2-enoate;Ethyl (E)-4-(diethoxyphosphoryl)but-2-enoate
CBNumber:
CB1664375
Molecular Formula:
C10H19O5P
Molecular Weight:
250.23
MDL Number:
MFCD00009192
MOL File:
10236-14-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:49:20
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Triethyl 4-phosphonocrotonate Properties

Boiling point 135 °C0.4 mm Hg(lit.)
Density 1.128 g/mL at 25 °C(lit.)
refractive index n20/D 1.455(lit.)
Flash point >230 °F
storage temp. Storage temp. 2-8°C
form Liquid
color Clear light yellow
InChI 1S/C10H19O5P/c1-4-13-10(11)8-7-9-16(12,14-5-2)15-6-3/h7-8H,4-6,9H2,1-3H3/b8-7+
InChIKey LXLODBXSCRTXFG-BQYQJAHWSA-N
SMILES CCOC(=O)\C=C\CP(=O)(OCC)OCC
CAS DataBase Reference 10236-14-3(CAS DataBase Reference)
UNSPSC Code 12352108
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29319090
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

Triethyl 4-phosphonocrotonate price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 116092 Triethyl 4-phosphonocrotonate, mixture of isomers technical grade, 90% 10236-14-3 10g $120 2026-04-30 Buy
Apolloscientific OR42028 Ethyl 4-(diethoxyphosphoryl)crotonate 92% 10236-14-3 1g $89 2026-06-04 Buy
Chem-Impex 36331 Triethyl 4-phosphonocrotonate, mixture of isomers ≥89%(GC) 10236-14-3 10G $126 2026-05-19 Buy
Chemenu CM342294 Triethyl 4-phosphonocrotonate 95%+ 10236-14-3 5g $120 2026-05-26 Buy
aablocks AA00076L Ethyl 4-(Diethoxyphosphoryl)But-2-Enoate 94% 10236-14-3 1g $52 2026-05-25 Buy
Product number Packaging Price Buy
116092 10g $120 Buy
OR42028 1g $89 Buy
36331 10G $126 Buy
CM342294 5g $120 Buy
AA00076L 1g $52 Buy

Triethyl 4-phosphonocrotonate Chemical Properties,Uses,Production

Chemical Properties

CLEAR LIGHT YELLOW LIQUID

Uses

Triethyl 4-phosphonocrotonate is used as a reactant for iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase, orally bioavailable GPR40 agonist synthesis, preparation of mGlu4R agonists and synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.

Uses

Reactant for:

  • Iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase
  • Stereoselective preparation of C1-C19 fragment of macrolide antibiotic aplyronine A using diastereoselective Nozaki-Hiyama-Kishi coupling reactions
  • Orally bioavailable GPR40 agonist synthesis
  • Synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2
  • Preaparation of mGlu4R agonists
  • Dearomatizing cyclization of nicotinyl-substituted esters and ketones

reaction suitability

reaction type: C-C Bond Formation

Triethyl 4-phosphonocrotonate synthesis

6065-32-3
122-52-1
10236-14-3
Synthesis of Triethyl 4-phosphonocrotonate from ethyl 4-bromocrotonate and Triethyl phosphite

Triethyl 4-phosphonocrotonate Preparation Products And Raw materials

Raw materials

Diethyl vinylphosphonate ethyl 4-bromocrotonate Triethyl phosphite Ethyl diazoacetate

Preparation Products

Triethyl 4-phosphonocrotonate Suppliers

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 452520369 sales@maya-r.com China 11693 57
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
Beijing innoChem Science & Technology Co.,Ltd. 400-810-7969 010-59572699 ningzi.li@inno-chem.com.cn China 6122 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
Energy Chemical 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Syntechem Co.,Ltd 57
Sinopharm Chemical Reagent Co,Ltd. 79
Maya High Purity Chemicals 57
Thermo Fisher Scientific 75
Beijing innoChem Science & Technology Co.,Ltd. 55

View Lastest Price from Triethyl 4-phosphonocrotonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TRIETHYL 4-PHOSPHONOCROTONATE pictures 2025-06-25 TRIETHYL 4-PHOSPHONOCROTONATE
10236-14-3
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd

Triethyl 4-phosphonocrotonate Spectrum

TRIETHYL 4-PHOSPHONOCROTONATE(10236-14-3)1HNMRTRIETHYL 4-PHOSPHONOCROTONATE(10236-14-3)IRTRIETHYL 4-PHOSPHONOCROTONATE(10236-14-3)FT-IRTRIETHYL 4-PHOSPHONOCROTONATE(10236-14-3)Raman

10236-14-3(Triethyl 4-phosphonocrotonate)Related Search:

Triethyl 3-phosphonopropionate Triethyl 4-phosphonobutyrate Triethyl 4-phosphonocrotonate Diethyl ethylphosphonate Ethylphosphonic acid
Methylphosphonic acid Dimethyl methylphosphonate DIMETHYL ETHYLPHOSPHONATE DIETHYL ALLYLPHOSPHONATE Methyldiethoxyphosphine
Diethyl methylphosphonate Dimethyl ethylphosphonite Dimethyl allylphosphonate Ethyl methylphosphonic acid Trimethyl 4-phosphonocrotonate
Diethyl ethylphosphonite TRIETHYL 3-METHYL-4-PHOSPHONOCROTONATE METHYL METHYLPHOSPHONIC ACID

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4-PHOSPHONOCROTONIC ACID TRIETHYL ESTER TRANS-ETHYL-4-(DIETHYLPHOSPHONO)CROTONATE TRIETHYL 4-PHOSPHONO-2-BUTENOATE TRIETHYL 4-PHOSPHONOCROTONATE, TECH., 90 %, MIXTURE OF ISOMERS Triethyl 4-phosphonocrotonate, predominantly trans, 92% triethyl 4-phosphonocrotonate, cis + trans triethyl 4-phosphonocrotonate, mixture of isomers triethyl trans-4-phosphono-2-butenoate Triethyl 4-phosphonocrotonate, cis + trans, tech. 90% Triethyl 4-phosphonocrotonate, 92%, predominantly trans (E)-Ethyl 4-(diethoxyphosphoryl)but-2-enoate Ethyl 4-(diethoxyphosphoryl)but-2-enoate, Ethyl 4-(diethylphosphono)crotonate Triethyl 4-phosphonocrotonate, predoMinantly trans, 92% 50GR Triethyl 4-phosphonocrotonate, mixture of isomers technical grade, 90% Triethyl 4-phosphonocrotonate, cis and trans, technical, 90% Ethyl 4-(diethoxyphosphoryl) 2-Butenoic acid, 4-(diethoxyphosphinyl)-, ethyl ester Ethyl (E)-4-(diethoxyphosphoryl)but-2-enoate Ethyl 4-(diethoxyphosphinyl)-2-butenoate Triethyl 4-phosphonocrotonate 10236-14-3 C2H5O2POCH2CHCHCO2C2H5 C10H19O5P C-C Bond Formation Horner-Wadsworth-Emmons Reagents Olefination Synthetic Reagents C-C Bond Formation Horner-Wadsworth-Emmons Reagents Olefination