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ChemicalBook >> CAS DataBase List >>3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine

3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine

3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine Structure
3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine structure
CAS No.
380238-10-8
Chemical Name:
3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
Synonyms
AKOS BBS-00006677;5-Methyl-2-[2-(trifluoromethyl)phenyl]pyrazol-3-amine;3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine;5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE;1H-Pyrazol-5-amine, 3-methyl-1-[2-(trifluoromethyl)phenyl]-;5-Amino-3-methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazole, 2-(5-Amino-3-methyl-1H-pyrazol-1-yl)benzotrifluoride
CBNumber:
CB1667679
Molecular Formula:
C11H10F3N3
Molecular Weight:
241.21
MDL Number:
MFCD02715834
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:49:20
Request For Quotation

3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine Properties

Boiling point 342.7±42.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 3.37±0.10(Predicted)
form powder
color Off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2933199090

3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FQA23810 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine 380238-10-8 1g $342.2 2026-06-04 Buy
Biosynth FQA23810 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine 380238-10-8 10g $2478 2026-06-04 Buy
Apolloscientific PC400534 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine ≥95% 380238-10-8 250mg $66 2026-06-04 Buy
Apolloscientific PC400534 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine ≥95% 380238-10-8 1g $153 2026-06-04 Buy
Matrix Scientific 101930 3-Methyl-1-(2-(trifluoromethyl)-phenyl)-1H-pyrazol-5-amine 380238-10-8 250.00mg $66 2026-05-18 Buy
Product number Packaging Price Buy
FQA23810 1g $342.2 Buy
FQA23810 10g $2478 Buy
PC400534 250mg $66 Buy
PC400534 1g $153 Buy
101930 250.00mg $66 Buy

3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine Chemical Properties,Uses,Production

Synthesis

3-Aminocrotononitrile

1118-61-2

1-[2-(Trifluoromethyl)phenyl]hydrazine

365-34-4

3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE

380238-10-8

GENERAL METHOD: 3-Aminobut-2-enenenitrile (10 mmol) was added to a suspension of (2-(trifluoromethyl)phenyl)hydrazine (10 mmol) in 12 M HCl-H2O (12 mL, 1:3 v/v). The reaction mixture was heated to reflux for 12 h, subsequently cooled to room temperature and neutralized with 2.5 M NaOH solution. The reaction mixture was extracted with dichloromethane (3 x 30 mL). The organic phases were combined, washed with saturated saline (20 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was ground with hexane to give a solid product, which was separated by filtration. If necessary, the product was purified by column chromatography.

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 11, p. 3429 - 3445
[2] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 136-137
[3] Journal of Combinatorial Chemistry, 2010, vol. 12, # 4, p. 510 - 517

3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine synthesis

1118-61-2
365-34-4
380238-10-8
Synthesis of 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine from 3-Aminocrotononitrile and 1-[2-(Trifluoromethyl)phenyl]hydrazine

3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine Preparation Products And Raw materials

Raw materials

3-Aminocrotononitrile 1-[2-(Trifluoromethyl)phenyl]hydrazine Hydrochloric acid Sodium hydroxide

Preparation Products

3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
Chem-Stone Co.,Ltd. 020-82185713,82185709 13418171485 sales@chem-stone.com China 743 56
Jiaxing Rich Biological Technology Co., Ltd. 0573-11111111-1111 18969316891 richmol@163.com China 445 50
BePharm Ltd 400-685-9117 market@bepharm.com China 15081 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22344 58
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
Hefei Hirisun Pharmatech Co., Ltd +8615056975894 shawn@hirisunpharm.com CHINA 9897 58
Shanxi Xuanran Import and Export Trade Co., Ltd. +8617735180244 mike_yan@xuanranglobal.com CHINA 4011 58
career henan chemical co +86-0371-86658258 factory@coreychem.com China 29780 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Supplier Advantage
Chem-Stone Co.,Ltd. 56
Jiaxing Rich Biological Technology Co., Ltd. 50
BePharm Ltd 60
Amadis Chemical Company Limited 58
Wuxi AppTec 58
Aikon International Limited 58
Hefei Hirisun Pharmatech Co., Ltd 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 58
career henan chemical co 58
Energy Chemical 58

View Lastest Price from 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine pictures 2020-01-13 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
380238-10-8
 $1.00 1g 99% 1ton Career Henan Chemical Co

380238-10-8(3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine)Related Search:

1-[2-(Trifluoromethyl)phenyl]-1H-pyrazol-5-amine 1H-Pyrazol-5-amine, 3-(1,1-dimethylethyl)-1-[2-(trifluoromethyl)phenyl]- 1H-Pyrazol-5-amine, 4-iodo-3-methyl-1-[2-(trifluoromethyl)phenyl]- 4-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine 3-Methyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
5-Methyl-2-(3-trifluoromethyl-phenyl)-2H-pyrazol-3-ylamine

1of2

5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE AKOS BBS-00006677 5-Amino-3-methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazole, 2-(5-Amino-3-methyl-1H-pyrazol-1-yl)benzotrifluoride 1H-Pyrazol-5-amine, 3-methyl-1-[2-(trifluoromethyl)phenyl]- 5-Methyl-2-[2-(trifluoromethyl)phenyl]pyrazol-3-amine 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine 380238-10-8