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ChemicalBook >> CAS DataBase List >>4-NITROPHENYL-2-METHOXYETHYL ETHER

4-NITROPHENYL-2-METHOXYETHYL ETHER

4-NITROPHENYL-2-METHOXYETHYL ETHER Structure
4-NITROPHENYL-2-METHOXYETHYL ETHER structure
CAS No.
22483-40-5
Chemical Name:
4-NITROPHENYL-2-METHOXYETHYL ETHER
Synonyms
SKL382;1-(2-Methoxyethoxy);4-NITROPHENYL-2-METHOXYETHYL ETHER;Benzene, 1-(2-methoxyethoxy)-4-nitro-
CBNumber:
CB1789113
Molecular Formula:
C9H11NO4
Molecular Weight:
197.19
MDL Number:
MFCD00463497
MOL File:
22483-40-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47
Product description Number Pack Size Price
1-(2-Methoxyethoxy)-4-nitrobenzene M304498 100mg $45
1-(2-Methoxyethoxy)-4-nitrobenzene M304498 500mg $60
1-(2-Methoxyethoxy)-4-nitrobenzene 95+% 119927 1g $78
1-(2-Methoxyethoxy)-4-nitrobenzene J96335 1g $22
1-(2-Methoxyethoxy)-4-nitrobenzene Z4445 1g $29
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4-NITROPHENYL-2-METHOXYETHYL ETHER Properties

Melting point 87 °C
Boiling point 317.0±22.0 °C(Predicted)
Density 1+-.0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H412
Precautionary statements  P261-P273-P305+P351+P338
HS Code  2909309090

4-NITROPHENYL-2-METHOXYETHYL ETHER price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M304498 1-(2-Methoxyethoxy)-4-nitrobenzene 22483-40-5 100mg $45 2021-12-16 Buy
TRC M304498 1-(2-Methoxyethoxy)-4-nitrobenzene 22483-40-5 500mg $60 2021-12-16 Buy
Matrix Scientific 119927 1-(2-Methoxyethoxy)-4-nitrobenzene 95+% 22483-40-5 1g $78 2021-12-16 Buy
AK Scientific J96335 1-(2-Methoxyethoxy)-4-nitrobenzene 22483-40-5 1g $22 2021-12-16 Buy
AK Scientific Z4445 1-(2-Methoxyethoxy)-4-nitrobenzene 22483-40-5 1g $29 2021-12-16 Buy
Product number Packaging Price Buy
M304498 100mg $45 Buy
M304498 500mg $60 Buy
119927 1g $78 Buy
J96335 1g $22 Buy
Z4445 1g $29 Buy

4-NITROPHENYL-2-METHOXYETHYL ETHER Chemical Properties,Uses,Production

Synthesis

4-Nitrophenol

100-02-7

1-Bromo-2-methoxyethane

6482-24-2

4-NITROPHENYL-2-METHOXYETHYL ETHER

22483-40-5

To a solution of N,N-dimethylformamide (DMF, 10 mL) of 4-nitrophenol (2.78 g, 20 mmol) and 2-bromoethyl methyl ether (3.6 g, 26 mmol) was added anhydrous potassium carbonate (K2CO3, 5.52 g, 40 mmol). The reaction mixture was stirred at 80 °C for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the reaction was subsequently quenched with deionized water (30 mL) and ethyl acetate (EtOAc, 40 mL). The organic and aqueous layers were separated and the aqueous layer was further extracted with ethyl acetate (2 x 25 mL). All organic extracts were combined, washed with saturated sodium chloride solution (brine, 2×20 mL), dried over anhydrous sodium sulfate (Na2SO4), and concentrated under reduced pressure to afford the target product, 4-nitrophenyl-2-methoxyethyl ether (3.9 g, 100% yield) as a yellow solid.

References

[1] Patent: WO2014/130693, 2014, A1. Location in patent: Paragraph 00544; 00546
[2] Patent: WO2015/6754, 2015, A2. Location in patent: Paragraph 00243; 00244
[3] European Journal of Medicinal Chemistry, 1980, vol. 15, # 5, p. 399 - 404
[4] Patent: US2005/277668, 2005, A1. Location in patent: Page/Page column 17

4-NITROPHENYL-2-METHOXYETHYL ETHER Preparation Products And Raw materials

Raw materials

4-Nitrophenol 2-Methoxyethanol 4-Fluoronitrobenzene 1-Bromo-2-methoxyethane Potassium carbonate
N,N-Dimethylformamide

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Preparation Products

4-(2-METHOXYETHOXY)ANILINE

4-NITROPHENYL-2-METHOXYETHYL ETHER Suppliers

Global( 64)Suppliers
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CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42934 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 18270980682 mlcheng@sunwaypharm.cn China 8667 57
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 4034 55
Nanjing Norris-Pharm Technology Co., Ltd 18652989687 sales@norris-pharm.com China 8878 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18209 56
Shanghai Tombiopharma Chemical Co. Ltd. 13391076197 tombiopharma@163.com China 4987 55
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
Career Henan Chemica Co 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Wuhan TCASChem Technology Co., Ltd. 55
Nanjing Norris-Pharm Technology Co., Ltd 55
9ding chemical ( Shanghai) Limited 56
Shanghai Tombiopharma Chemical Co. Ltd. 55

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4-NITROPHENYL-2-METHOXYETHYL ETHER 1-(2-Methoxyethoxy) Benzene, 1-(2-methoxyethoxy)-4-nitro- SKL382 22483-40-5