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SMS2-IN-1

SMS2-IN-1 Structure
SMS2-IN-1 structure
CAS No.
2098890-15-2
Chemical Name:
SMS2-IN-1
Synonyms
JUN90152;SMS2-IN-1;SMS2 IN 1,SMS2IN1,SMS-2-IN-1;1-methylcyclopropyl 4-(3-((3-((3,5-bis(trifluoromethyl)benzyl)(methyl)carbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy)propyl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-[3-[[3-[[[[3,5-bis(trifluoromethyl)phenyl]methyl]methylamino]carbonyl]-1,2-dihydro-1-methyl-2-oxo-4-quinolinyl]oxy]propyl]-, 1-methylcyclopropyl ester
CBNumber:
CB18054545
Molecular Formula:
C34H37F6N3O5
Molecular Weight:
681.67
MDL Number:
MFCD31813610
MOL File:
2098890-15-2.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:42
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SMS2-IN-1 Properties

Boiling point 685.7±55.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 27.78 mg/mL (40.75 mM; Need ultrasonic)
pka -1.20±0.20(Predicted)
form Solid
color White to off-white

SMS2-IN-1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth YID89015 SMS2-IN-1 2098890-15-2 25mg $1310 2026-06-05 Buy
Biosynth YID89015 SMS2-IN-1 2098890-15-2 50mg $1822.5 2026-06-05 Buy
ChemScene CS-0022834 SMS2-IN-1 98.00% 2098890-15-2 1mg $232 2026-06-04 Buy
ChemScene CS-0022834 SMS2-IN-1 98.00% 2098890-15-2 5mg $487 2026-06-04 Buy
ChemScene CS-0022834 SMS2-IN-1 98.00% 2098890-15-2 10mg $867 2026-06-04 Buy
Product number Packaging Price Buy
YID89015 25mg $1310 Buy
YID89015 50mg $1822.5 Buy
CS-0022834 1mg $232 Buy
CS-0022834 5mg $487 Buy
CS-0022834 10mg $867 Buy

SMS2-IN-1 Chemical Properties, Uses, Production

Uses

SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM)[1].

References

[1] Adachi R, et al. Discovery and characterization of selective human sphingomyelin synthase 2 inhibitors. Eur J Med Chem. 2017 Aug 18;136:283-293. DOI:10.1016/j.ejmech.2017.04.067

SMS2-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

SMS2-IN-1 Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
Shanghai Changyu Medical Technology Co. Ltd. +86-13301875428 sales@changyuhe.com China 300 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762 sales@hasunny.com China 2377 58
InvivoChem 13549236410 sales@invivochem.cn China 6745 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29982 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Guangzhou Ruidi Biotechnology Co., Ltd. 020-82099279 18988941402 sales@ubiochem.com China 9998 58
Shenzhen Shengda Pharma Limited 755-85269922 sales@shengdapharm.com CHINA 310 58
Supplier Advantage
Shanghai Changyu Medical Technology Co. Ltd. 58
TargetMol Chemicals Inc. 58
InvivoChem 58
Kaifeng Mingren Pharmaceutical Co.,LTD 58
InvivoChem 58
https://hanhongsci.com/ 58
TargetMol Chemicals Inc. 58
Guangzhou Ruidi Biotechnology Co., Ltd. 58
Shenzhen Shengda Pharma Limited 58

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SMS2-IN-1 1-methylcyclopropyl 4-(3-((3-((3,5-bis(trifluoromethyl)benzyl)(methyl)carbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy)propyl)piperidine-1-carboxylate JUN90152 SMS2 IN 1,SMS2IN1,SMS-2-IN-1 1-Piperidinecarboxylic acid, 4-[3-[[3-[[[[3,5-bis(trifluoromethyl)phenyl]methyl]methylamino]carbonyl]-1,2-dihydro-1-methyl-2-oxo-4-quinolinyl]oxy]propyl]-, 1-methylcyclopropyl ester 2098890-15-2