coformycin
- CAS No.
- 11033-22-0
- Chemical Name:
- coformycin
- Synonyms
- NSC 277817;coformycin;5-d)(1,3)diazepin-8-ol,3,4,7,8-tetrahydro-3-beta-d-ribofuranosyl-imidazo((;(8R)-3-β-D-Ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol;(8R)-3,4,7,8-Tetrahydro-3-β-D-ribofuranosylimidazo[4,5-d][1,3]diazepin-8-ol;(r)-3,4,7,8-tetrahydro-3-beta-d-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-o;Imidazo[4,5-d][1,3]diazepin-8-ol, 3,4,7,8-tetrahydro-3-β-D-ribofuranosyl-, (8R)-
- CBNumber:
- CB1870732
- Molecular Formula:
- C11H16N4O5
- Molecular Weight:
- 284.27
- MDL Number:
- MFCD00036884
- MOL File:
- 11033-22-0.mol
- MSDS File:
- SDS
| Melting point | 182-184 °C |
|---|---|
| Boiling point | 692.670±65.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.964±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| pka | 12.826±0.20(predicted) |
| FDA UNII | E49510ZL0H |
coformycin Chemical Properties,Uses,Production
Description
Coformycin is isolated from Nocardia interforma along with formycin. Coformycin shows a synergistic effect with formycin on Yoshida rat sarcoma cells because of its strong inhibition of adenosine deaminase, which inactivates formycin. Coformycin, having a characteristic seven-membered ring base moiety, is thought to be a typical example of a “transition-state analog” in the adenosine deaminase reaction. 2_x0002_-Deoxycoformycin (19b) has also been isolated also .
Definition
ChEBI: An N-glycosyl in which (8R)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol is attached to ribofuranose via a beta-N3-glycosidic bond. compound The parent of the class of coformycins.
coformycin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu NoVi Biotechnology Co., Ltd. | 028-81458053 | novibiotech@163.com sales@novi-biotech.com | China | 226 | 55 |
| Nanjing crow LuNing pharmaceutical technology co., LTD | 13382066392 | CHINA | 4851 | 58 | |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
