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lonazolac

CAS No.
53808-88-1
Chemical Name:
lonazolac
Synonyms
lonazolac;LONAZOLAC CALCIUM;Lonazolac, 10 mM in DMSO;3-(4-Chlorophenyl)-1-phenyl-1H-pyrazole-4-acetic acid;1H-Pyrazole-4-acetic acid, 3-(4-chlorophenyl)-1-phenyl-;2-[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]acetic acid;anti-inflammatory,antirheumatic,non-acidic,Inhibitor,inhibit,Lonazolac
CBNumber:
CB1936094
Molecular Formula:
C17H13ClN2O2
Molecular Weight:
312.755
MDL Number:
MFCD00866046
MOL File:
53808-88-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:28

lonazolac Properties

Melting point 150-151°
form Solid
pka 4.3(at 25℃)
color Light yellow to yellow
FDA UNII 13097143QI
ATC code M01AB09

SAFETY

Risk and Safety Statements

Toxicity LD50 in male mice, rats (mg/kg): 195, 165 i.v. (Riedel)

lonazolac price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth DCA80888 2-[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]acetic acid 53808-88-1 100mg $337 2026-06-04 Buy
Biosynth DCA80888 2-[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]acetic acid 53808-88-1 1g $861.4 2026-06-04 Buy
ChemScene CS-0234447 Lonazolac 99.59% 53808-88-1 5mg $67 2026-06-04 Buy
ChemScene CS-0234447 Lonazolac 99.59% 53808-88-1 10mg $93 2026-06-04 Buy
ChemScene CS-0234447 Lonazolac 99.59% 53808-88-1 25mg $149 2026-06-04 Buy
Product number Packaging Price Buy
DCA80888 100mg $337 Buy
DCA80888 1g $861.4 Buy
CS-0234447 5mg $67 Buy
CS-0234447 10mg $93 Buy
CS-0234447 25mg $149 Buy

lonazolac Chemical Properties,Uses,Production

Originator

Irriten,Tosse,W. Germany,1981

Definition

ChEBI: A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 3-(4-chlorophenyl)-1-phenylpyrazol-4-yl group.

Manufacturing Process

17.6 g 1-phenyl-3-(p-chlorophenyl)-pyrazol-4-acetonitrile and 180 ml 25% aqueous hydrochloric acid were mixed and heated to the boiling temperature under reflux for 6 hours. To the mixture was then added dropwise concentrated aqueous sodium hydroxide until the pH of the mixture reached a value in the range from 3 to 5. The free pyrazol-4-acetic acid precipitated thereby was filtered off, redissolved in dilute aqueous sodium hydroxide, the solution cleared by treatment with activated carbon, and the pyrazol-4-acetic acid precipitated by acidifying the solution by the addition of dilute mineral acid, sulfuric acid. The filtered acid was crystallized from a mixture of ethanol and water. 17.1 g 1-phenyl-3-(p-chlorophenyl)pyrazol-4-acetic acid, melting at 148°C to 150°C, were obtained, representing a yield of 91%.

Therapeutic Function

Antiinflammatory

lonazolac Preparation Products And Raw materials

Raw materials

Preparation Products

lonazolac Suppliers

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Hopschain Chemical Co.,Ltd. 85528066 13775048983 sales@hopschem.com China 31548 55
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5987 58
Foshan Heshuo Pharm technology Co., ltd 15363639686 heshuoyiyao@hotmail.com China 2490 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Shanghai Yaoheping Biopharmaceutical Technology Co., Ltd 57540919 13120888836 lily@yhp-biomedicine.com China 9246 58
Wuxi Lihengsheng Biopharmaceutical Technology Co., Ltd 15250805028 15250805028 649163353@qq.com China 8000 58
Aladdin Scientific tp@aladdinsci.com United States 50089 58
2-[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]acetic acid lonazolac LONAZOLAC CALCIUM 3-(4-Chlorophenyl)-1-phenyl-1H-pyrazole-4-acetic acid 1H-Pyrazole-4-acetic acid, 3-(4-chlorophenyl)-1-phenyl- anti-inflammatory,antirheumatic,non-acidic,Inhibitor,inhibit,Lonazolac Lonazolac, 10 mM in DMSO 53808-88-1 2C17H12ClN2O2Ca