ChemicalBook >> CAS DataBase List >>Hydroxyfasudil monohydrochloride
Hydroxyfasudil monohydrochloride
- CAS No.
- 155558-32-0
- Chemical Name:
- Hydroxyfasudil monohydrochloride
- Synonyms
- Hydroxyfasudil hydrochloride hydrate;Fasudil Hydroxy;Hydroxyfasudil HCl;Fasudil Impurity 7 HCl;Hydroxyfasudil (HA-1100);Hydroxyfasudil HCl (HA1100);Hydroxyfasudil Hydrochloride;Hydroxyfasudil (HA-1100) HCl;Hydroxyfasudil monohydrochloride;HA 1100 hydrochloride (Hydroxyfasudil)
- CBNumber:
- CB1973040
- Molecular Formula:
- C14H18ClN3O3S
- Molecular Weight:
- 343.82902
- MDL Number:
- MFCD06411567
- MOL File:
- 155558-32-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-09-12 18:50:06
| Melting point | >250 (dec.) |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: >5mg/mL |
| form | solid |
| color | white |
| Water Solubility | Soluble in water (20mM) |
| InChI | InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H |
| InChIKey | XWWFOUVDVJGNNG-UHFFFAOYSA-N |
| SMILES | c1c(S(=O)(=O)N2CCNCCC2)c2ccnc(O)c2cc1.Cl |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
Hydroxyfasudil monohydrochloride price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H4413 | Hydroxyfasudil hydrochloride hydrate ≥98% (HPLC), solid | 155558-32-0 | 5mg | $315 | 2026-04-30 | Buy |
| Sigma-Aldrich | 390602 | Hydroxyfasudil | 155558-32-0 | 2mg | $175 | 2026-04-30 | Buy |
| TCI Chemical | H1745 | Hydroxyfasudil Hydrochloride | 155558-32-0 | 10MG | $121 | 2026-04-30 | Buy |
| TCI Chemical | H1745 | Hydroxyfasudil Hydrochloride | 155558-32-0 | 50MG | $396 | 2026-04-30 | Buy |
| Cayman Chemical | 14413 | HA-1100 (hydrochloride) ≥98% | 155558-32-0 | 1mg | $36 | 2026-04-30 | Buy |
Hydroxyfasudil monohydrochloride Chemical Properties, Uses, Production
Chemical Properties
Off-White Solid
Uses
A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.
General Description
A cell-permeable, hydroxylated metabolite of HA 1077 (Fasudil; Cat. No. 371970) that displays anti-anginal properties. Acts as an ATP-competitive and a reversible inhibitor of Rho-kinase (IC50 = 0.9 and 1.8 μM using a peptide and MLC as substrate, respectively) with ~100-fold greater selectivity over MLCK, MRCKβ, and PKC. Reported to inhibit the Rho kinase-mediated contraction both in vitro and in vivo.
Biochem/physiol Actions
Cell permeable: yes
storage
-20°C
Hydroxyfasudil monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Hydroxyfasudil monohydrochloride Suppliers
Global Suppliers ( 120)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Ran enzyme Biotechnology Co., Ltd. | 0512-0512-62793604 18015430729 | 116667374@qq.com | China | 132 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 997 | 58 |
| SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD | 13816107857 | sales@fortunechem-sh.com | China | 981 | 58 |
View Latest Price from Hydroxyfasudil monohydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Hydroxyfasudil Hydrochloride
155558-32-0
|
$55.00-127.00 | 99.82% | 10g | TargetMol Chemicals Inc. |
-
- Hydroxyfasudil Hydrochloride
155558-32-0
- $55.00-127.00
- 99.82%
- TargetMol Chemicals Inc.
155558-32-0 (Hydroxyfasudil monohydrochloride) Related Search:
5-Quinolinesulfonic acid, 2-methyl-
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1of4
HA-1100 HYDROCHLORIDE;HA 1100 HYDROCHLORIDE;HA1100 HYDROCHLORIDE
5-(1,4-diazepan-1-ylsulfonyl)-2h-isoquinolin-1-one
Hydroxyfasudil hydrochloride (HA-1100 hydrochloride)
Hydroxyfasudil - CAS 155558-32-0 - Calbiochem
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1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1)
Fasudil Impurity 7 HCl
Fasudil Hydroxy
5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol hydrochloride
5-[(1,4-Diazepan-1-yl)sulfonyl]isoquinolin-1(2H)-one Hydrochloride
Hydroxyfasudil HCl (HA1100)
5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one,hydrochloride
HA-1100,ROCK,Hydroxyfasudil Hydrochloride,Hydroxyfasudil,Rho-associated kinase,HA 1100,inhibit,HA1100,Rho-kinase,Rho-associated protein kinase,ROK,Inhibitor
Hydroxyfasudil hydrochloride hydrate Hydroxyfasudil hydrochloride
HA 1100 hydrochloride (Hydroxyfasudil)
HA 1100 hydrochloride (Hydroxyfasudil), Rho-kinase inhibitor
Hydroxyfasudil Hydrochloride, 10 mM in DMSO
Hydroxyfasudil hydrochloride hydrate 98+
5-(1,4-Diazepan-1-Ylsulfonyl)-1-Isoquinolinol Hydrochloride
Hydroxyfasudil hydrochloride hydrate
Hydroxyfasudil monohydrochloride
155558-32-0
C14H17N3O3SHCl
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals
