6-Quinolineacetic acid
- CAS No.
- 5622-34-4
- Chemical Name:
- 6-Quinolineacetic acid
- Synonyms
- 2-(quinolin-6-yl)acetic acid;OK-J-05024;6-QuinolineAceticAci;6-Quinolylacetic acid;Quinolin-6-Yl-Acetic Acid;6-Quinoline Acetic Acid, 97+%;6-QUINOLINEACETIC ACID ISO 9001：2015 REACH;6-Quinolineacetic acid (7CI, 8CI, 9CI, ACI);6-Quinolylacetic acid 2-(Quinolin-6-yl)acetic acid
- CBNumber:
- CB1980901
- Molecular Formula:
- C11H9NO2
- Molecular Weight:
- 187.19
- MDL Number:
- MFCD07776794
- MOL File:
- 5622-34-4.mol
- MSDS File:
- SDS
| Melting point | 225 °C (decomp) |
|---|---|
| Boiling point | 388.8±17.0 °C(Predicted) |
| Density | 1.297±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.65±0.30(Predicted) |
| Appearance | Off-white to brown Solid |
| InChI | InChI=1S/C11H9NO2/c13-11(14)7-8-3-4-10-9(6-8)2-1-5-12-10/h1-6H,7H2,(H,13,14) |
| InChIKey | CFVILHFXMRQYSG-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC(CC(O)=O)=CC=2)C=CC=1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310+P330-P405-P501 |
| HS Code | 2933499090 |
6-Quinolineacetic acid price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR350332 | 6-Quinolineacetic acid >95% | 5622-34-4 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR350332 | 6-Quinolineacetic acid >95% | 5622-34-4 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR350332 | 6-Quinolineacetic acid >95% | 5622-34-4 | 5g | $71 | 2026-06-04 | Buy |
| Apolloscientific | OR350332 | 6-Quinolineacetic acid >95% | 5622-34-4 | 25g | $294 | 2026-06-04 | Buy |
| Apolloscientific | OR350332 | 6-Quinolineacetic acid >95% | 5622-34-4 | 100g | $1171 | 2026-06-04 | Buy |
6-Quinolineacetic acid Chemical Properties, Uses, Production
Synthesis
1197-55-3
56-81-5
5622-34-4
The general procedure for the synthesis of 6-quinolineacetic acid from p-aminophenylacetic acid (20 g, 0.132 mol) and glycerol (51 g, 0.555 mol) is as follows: aminophenylacetic acid, FeSO4 (4.9 g, 0.032 mol), glycerol, PhNO2 (10.5 g, 0.086 mol) and concentrated H2SO4 (23 mL) were mixed, heated to 200°C and maintained for 5 hours. Upon completion of the reaction, the pH of the reaction mixture was adjusted to 10 with 4N NaOH aqueous solution. the reaction mixture was filtered and the clarified filtrate was acidified with AcOH to pH ca. 5. The resulting precipitate was collected by filtration to afford 6-quinolineacetic acid (12.5 g, 51% yield) as a brown solid. tLC conditions: 20% MeOH/CH2Cl2, Rf=0.2. 1H NMR ( 300MHz, DMSO-d6) δ ppm: 8.85 (m, 1H), 8.31-8.28 (m, 1H), 7.96 (d, J=8.3Hz, 1H), 7.82 (m, 1H), 7.67-7.64 (m, 1H), 7.50-7.49 (m, 1H), 3.78 (s, 2H).
References
[1] Patent: WO2013/19682, 2013, A1. Location in patent: Page/Page column 117
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 17, p. 6651 - 6665
[3] Patent: WO2007/138472, 2007, A2. Location in patent: Page/Page column 28
[4] Journal of the American Chemical Society, 1948, vol. 70, p. 2843,2945
[5] Patent: WO2009/137404, 2009, A1. Location in patent: Page/Page column 60
6-Quinolineacetic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Okeanos Tech Co,. Ltd. | 01062651721 18610486005 | info@okeanos.com.cn | China | 567 | 58 |
| ITIC MEDCHEM(SUZHOU) CO.,LTD. | 0512-68323967 18015559028 | sales@iticmedchem.com | China | 528 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 984 | 62 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
View Latest Price from 6-Quinolineacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 6-QUINOLINEACETIC ACID
5622-34-4
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-07-06 | 6-QUINOLINEACETIC ACID
5622-34-4
|
$1.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- 6-QUINOLINEACETIC ACID
5622-34-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 6-QUINOLINEACETIC ACID
5622-34-4
- $1.00
- 98%
- Career Henan Chemical Co
