Pipobroman
- CAS No.
- 54-91-1
- Chemical Name:
- Pipobroman
- Synonyms
- Amedel;A-8103;Vercyte;NSC-25154;Pipobroman;Pipobroman, 10 mM in DMSO;1,4-Bis(3-bromopropionyl)piperazine;1,4-Bis(3-bromo-1-oxopropyl)piperadine;1,4-Bis(3-bromo-1-oxopropyl)piperazine;1,1'-(1,4-Piperazinediyl)bis[3-bromo]-1-propanone
- CBNumber:
- CB21016761
- Molecular Formula:
- C10H16Br2N2O2
- Molecular Weight:
- 356.05
- MDL Number:
- MFCD00866372
- MOL File:
- 54-91-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Pipobroman ≥98% (HPLC) | SML3602 | 10MG | $76.3 |
| Pipobroman ≥98% (HPLC) | SML3602 | 50MG | $309 |
| Pipobroman | TRC-P490600-1G | 1g | $434 |
| Pipobroman 99.81% | CS-5085 | 100mg | $110 |
| Pipobroman | BA3929 | 100mg | $76 |
| Melting point | 106-107℃ |
|---|---|
| Boiling point | 487℃ |
| Density | 1.691 |
| refractive index | 1.6220 (estimate) |
| Flash point | 248℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | -0.56±0.70(Predicted) |
| color | Crystals from H2O |
| InChI | 1S/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2 |
| InChIKey | NJBFOOCLYDNZJN-UHFFFAOYSA-N |
| SMILES | BrCCC(=O)N1CCN(CC1)C(=O)CCBr |
| FDA UNII | 6Q99RDT97R |
| Proposition 65 List | Pipobroman |
| ATC code | L01AX02 |
| EPA Substance Registry System | Pipobroman (54-91-1) |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335-H351-H361 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | WGK 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral |
| Hazardous Substances Data | 54-91-1(Hazardous Substances Data) |
| Toxicity | LD50 orl-rat: 220 mg/kg IYKEDH 4,467,73 |
Pipobroman price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3602 | Pipobroman ≥98% (HPLC) | 54-91-1 | 10MG | $76.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML3602 | Pipobroman ≥98% (HPLC) | 54-91-1 | 50MG | $309 | 2026-04-30 | Buy |
| TRC | TRC-P490600-1G | Pipobroman | 54-91-1 | 1g | $434 | 2026-06-03 | Buy |
| ChemScene | CS-5085 | Pipobroman 99.81% | 54-91-1 | 100mg | $110 | 2026-06-04 | Buy |
| ApexBio Technology | BA3929 | Pipobroman | 54-91-1 | 100mg | $76 | 2026-05-06 | Buy |
Pipobroman Chemical Properties,Uses,Production
Originator
Vercyte ,Abbott ,US ,1966
Uses
diuretic, antihypertensive
Definition
ChEBI: Pipobroman is an N-acylpiperazine that is piperazine in which each of the nitrogens has been acylated by a 3-bromopropionoyl group. An anti-cancer drug. It has a role as an antineoplastic agent and an alkylating agent. It is a N-acylpiperazine, a tertiary carboxamide and an organobromine compound.
Manufacturing Process
To a solution of 17.2 g (0.10 mol) of 3-bromopropionyl chloride in 100 ml of anhydrous benzene was added dropwise with stirring a solution of 8.6 g (0.10 mol) of anhydrous piperazine in 20 ml of dry chloroform over a period of 30 minutes. The temperature rose spontaneously to 45°C during the addition. After the temperature ceased to rise, stirring was continued for another hour. The reaction mixture was then filtered to remove the piperazine hydrochloride by-product. The filtrate was evaporated to dryness and the residue recrystallized from ethanol to obtain the desired N,N'-bis-(3bromopropionyl)piperazine as a white crystalline solid melting at 103°C to 104°C. The identity of the product was further established by elemental analysis.
brand name
Vercyte (Abbott).
Therapeutic Function
Antineoplastic
Biological Activity
Pipobroman is an alkylating agent th at is used as anti-cancer drug. It also has clinical activity in polycythemia vera and thrombocythemia.
Safety Profile
Poison by ingestion,subcutaneous and intraperitoneal routes. An experimentalteratogen. Other experimental reproductive effects.Human mutation data reported. When heated todecomposition it emits very toxic fumes of Br- and NOx.
Pipobroman Preparation Products And Raw materials
Pipobroman Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +86-13289823923 | 1090@dideu.com | China | 8651 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Chongqing jooe co., ltd | +86-15223382610 | info@jooe.com | China | 15942 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
View Lastest Price from Pipobroman manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Pipobroman
54-91-1
|
$35.00-48.00 | 97.08% | 10g | TargetMol Chemicals Inc. |
-
- Pipobroman
54-91-1
- $35.00-48.00
- 97.08%
- TargetMol Chemicals Inc.
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