Polygalacic acid
- CAS No.
- 22338-71-2
- Chemical Name:
- Polygalacic acid
- Synonyms
- Polygalacic;Virgaureagenin G;Polygalacicaci;Polygalacic acid;Polygalacic acid, >=98%;Polygalacic acid (Standard);Virgaureagenin G，Polygalacic acid;(4R)-2β,3β,16α,23-Tetrahydroxyolean-12-en-28-oic acid;Polygalacic acid, 98%, from Polygala tenuifolia Willd.;(2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid
- CBNumber:
- CB21040708
- Molecular Formula:
- C30H48O6
- Molecular Weight:
- 504.7
- MDL Number:
- MFCD12911690
- MOL File:
- 22338-71-2.mol
- MSDS File:
- SDS
| Melting point | 300-305 °C (sublm) |
|---|---|
| Boiling point | 638.1±55.0 °C(Predicted) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 4.41±0.70(Predicted) |
| color | White to off-white |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
Polygalacic acid price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30620 | Polygalacic Acid ≥95% | 22338-71-2 | 500μg | $95 | 2026-04-30 | Buy |
| Cayman Chemical | 30620 | Polygalacic Acid ≥95% | 22338-71-2 | 1mg | $178 | 2026-04-30 | Buy |
| Cayman Chemical | 30620 | Polygalacic Acid ≥95% | 22338-71-2 | 5mg | $601 | 2026-04-30 | Buy |
| Cayman Chemical | 30620 | Polygalacic Acid ≥95% | 22338-71-2 | 10mg | $922 | 2026-04-30 | Buy |
| Usbiological | 300805 | Polygalacic acid ≥98% | 22338-71-2 | 5mg | $525 | 2026-06-03 | Buy |
Polygalacic acid Chemical Properties,Uses,Production
Uses
Polygalacic acid can be used to calm the nerves, eliminate phlegm, reduce swelling, etc. It is mostly used clinically to treat bronchitis, induce labor, and induce labor.
Biological Activity
Polygalacic acid is a triterpenoid tetrahydroxy acid isolated from Polygala paenea L.. It (0-100μM; 24h) can significantly reduce the mRNA expression of MMP-3, MMP-9, MMP-13 and COX-2, and the expression of these factors can be significantly increased by IL-1β in a dose-dependent manner .
in vitro
Polygalacic acid (0-100 μM; 24 hours) significantly decreases the mRNAexpressions of MMP-3, MMP-9, MMP-13, and COX-2, which are significantly increased by IL-1β, in a In a dose-dependent manner. Polygalacic acid (0-100 μM; 6 hours) decreases the expression of phosphor-p38, phosphor-Erk, and phosphor-Jnk induced by IL-1β, phosphor-p65 is not reduced by polygalacic acid.
RT-PCR
| Cell Line: | Chondrocyte cells |
| Concentration: | 50 μM; 100 μM |
| Incubation Time: | 24 hours |
| Result: | Suppressed IL-1β-induced COX-2, MMP3, MMP9, and MMP13 mRNA expression. |
Western Blot Analysis
| Cell Line: | Chondrocyte cells | Concentration: | 50 μM; 100 μM |
| Incubation Time : | 6 hours |
| Result: | Inhibited the IL-1β-induced activation of the MAPK pathway in chondrocytes. |
IC 50
AChE
Polygalacic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Shenzhen Sungening Bio-Tech Co., Ltd | +86-0755-89668383 | sales@sungening.com | China | 1319 | 65 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Chengdu Climax Biotech Co., Ltd. | 028-83311324 1278112614 | climaxbiotech@gmail.com | China | 925 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Shanghai Ruji Biology Technology Co., Ltd. | +86-21-65211385-8001 36031160 | sales@shruji.com | China | 3223 | 55 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
View Lastest Price from Polygalacic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Polygalacic acid
22338-71-2
|
$89.00 | 99.82% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-07-06 | Polygalacic acid
22338-71-2
|
$1.00 | 1g | 99% | 100KG | Career Henan Chemical Co |
-
- Polygalacic acid
22338-71-2
- $89.00
- 99.82%
- TargetMol Chemicals Inc.
-
- Polygalacic acid
22338-71-2
- $1.00
- 99%
- Career Henan Chemical Co
