Benzonitrile, 4-amino-3-methoxy- (9CI)
- CAS No.
- 177476-76-5
- Chemical Name:
- Benzonitrile, 4-amino-3-methoxy- (9CI)
- Synonyms
- 3-Methoxy-4-aminobenz;4-Cyano-2-Methoxy-aniline;3-Methoxy-4-aminobenzonitrile;Benzonitrile, 4-aMino-3-Methoxy-;4-Amino-3-methoxybenzenecarbonitrile;Benzonitrile, 4-amino-3-methoxy- (9CI)
- CBNumber:
- CB21046755
- Molecular Formula:
- C8H8N2O
- Molecular Weight:
- 148.16
- MDL Number:
- MFCD13250177
- MOL File:
- 177476-76-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H302-H332-H315-H312-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HazardClass | IRRITANT |
| HS Code | 2921420090 |
Benzonitrile, 4-amino-3-methoxy- (9CI) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 50150 | 4-CYANO-2-METHOXY-ANILINE 95% | 177476-76-5 | 1G | $73 | 2026-04-30 | Buy |
| AstaTech | 50150 | 4-CYANO-2-METHOXY-ANILINE 95% | 177476-76-5 | 5G | $286 | 2026-04-30 | Buy |
| Apolloscientific | OR321008 | 4-Cyano-2-methoxy-aniline >97% | 177476-76-5 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR321008 | 4-Cyano-2-methoxy-aniline >97% | 177476-76-5 | 1g | $26 | 2026-06-04 | Buy |
| Apolloscientific | OR321008 | 4-Cyano-2-methoxy-aniline >97% | 177476-76-5 | 5g | $104 | 2026-06-04 | Buy |
Benzonitrile, 4-amino-3-methoxy- (9CI) Chemical Properties, Uses, Production
Synthesis
177476-75-4
177476-76-5
The general procedure for the synthesis of 3-methoxy-4-aminobenzonitrile from 3-methoxy-4-nitrobenzonitrile was as follows: 3-methoxy-4-nitrobenzonitrile (11.4 g, 64 mmol) was suspended in ethyl acetate (60 mL) and 10% Pd/C catalyst (1 g) was added. The reaction mixture was placed in a Parr reactor under hydrogen atmosphere and vigorously shaken at 50 psi for 45 min at room temperature. Upon completion of the reaction, the mixture was filtered through a short pad of diatomaceous earth and the filtrate was concentrated to afford 4-amino-3-methoxybenzonitrile as a yellow oil, which rapidly solidified to a solid (9.5 g, 95% yield).
References
[1] Patent: US2011/130398, 2011, A1. Location in patent: Page/Page column 34
[2] Patent: US2011/269809, 2011, A1. Location in patent: Page/Page column 13
[3] Patent: US2012/46306, 2012, A1. Location in patent: Page/Page column 33
[4] Journal of Medicinal Chemistry, 2000, vol. 43, # 6, p. 1187 - 1202
[5] Patent: US5506252, 1996, A
Benzonitrile, 4-amino-3-methoxy- (9CI) Preparation Products And Raw materials
Benzonitrile, 4-amino-3-methoxy- (9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai potentpharm CO.,Ltd | (86) 21 51969655 | China | 486 | 22 | |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2853 | 52 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Xinyanhe Pharmatech Co.,Ltd | 0519-85252752 15366845260 | taihuaren@vip.163.com | China | 1031 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
View Latest Price from Benzonitrile, 4-amino-3-methoxy- (9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-31 | Benzonitrile, 4-amino-3-methoxy- (9CI)
177476-76-5
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Benzonitrile, 4-amino-3-methoxy- (9CI)
177476-76-5
- $1.00
- 99%
- Career Henan Chemical Co
