Pyridine, 3-chloro-2-(chloromethyl)- (9CI)
- CAS No.
- 185315-53-1
- Chemical Name:
- Pyridine, 3-chloro-2-(chloromethyl)- (9CI)
- Synonyms
- 3-Chloro-2-(chloromethyl);3-Chloro-2-(chloroMethyl)pyridine;3-chloro-pyridin-2-ylMethyl chloride;Pyridine, 3-chloro-2-(chloromethyl)-;Pyridine, 3-chloro-2-(chloromethyl)- (9CI)
- CBNumber:
- CB21057351
- Molecular Formula:
- C6H5Cl2N
- Molecular Weight:
- 162.02
- MDL Number:
- MFCD10697613
- MOL File:
- 185315-53-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Chloro-2-(chloromethyl)pyridine 98% | AS43731-A | 1g | $253 |
| 3-Chloro-2-(chloromethyl)pyridine 98% | AS43731-A | 5g | $915 |
| 3-Chloro-2-(chloromethyl)pyridine | 207494 | 250.00mg | $66 |
| 3-Chloro-2-(chloromethyl)pyridine | 207494 | 1.00g | $160 |
| 3-Chloro-2-(chloromethyl)pyridine | 207494 | 5.00g | $656 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Pyridine, 3-chloro-2-(chloromethyl)- (9CI) price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS43731-A | 3-Chloro-2-(chloromethyl)pyridine 98% | 185315-53-1 | 1g | $253 | 2026-06-04 | Buy |
| Activate Scientific | AS43731-A | 3-Chloro-2-(chloromethyl)pyridine 98% | 185315-53-1 | 5g | $915 | 2026-06-04 | Buy |
| Matrix Scientific | 207494 | 3-Chloro-2-(chloromethyl)pyridine | 185315-53-1 | 250.00mg | $66 | 2026-05-18 | Buy |
| Matrix Scientific | 207494 | 3-Chloro-2-(chloromethyl)pyridine | 185315-53-1 | 1.00g | $160 | 2026-05-18 | Buy |
| Matrix Scientific | 207494 | 3-Chloro-2-(chloromethyl)pyridine | 185315-53-1 | 5.00g | $656 | 2026-05-18 | Buy |
Pyridine, 3-chloro-2-(chloromethyl)- (9CI) Chemical Properties,Uses,Production
Synthesis
60588-81-0
185315-53-1
General procedure for the synthesis of 3-chloro-2-(chloromethyl)pyridine from 3-chloropyridine-2-methanol: To a solution of compound 31 (300 mg, 2.1 mmol) in dichloromethane (DCM, 4 mL) was added N,N-diisopropylethylamine (DIE A, 539 mg, 4.2 mmol) at 0 °C, followed by slow dropwise addition of mesyl chloride (MsCl, 263 mg, 2.3 mmol). The reaction mixture was stirred at 0 °C for 3 hours. Upon completion of the reaction, the reaction was quenched by the addition of water and the mixture was extracted with dichloromethane. The organic phase was washed sequentially with saturated sodium bicarbonate (NaHCO3) solution and brine and dried over anhydrous sodium sulfate (Na2SO4). After filtration, the filtrate was concentrated under reduced pressure to give compound 32 (240 mg, 69% yield) as a yellow oil.
References
[1] Patent: WO2015/143164, 2015, A1. Location in patent: Page/Page column 119-120
[2] Journal of Medicinal Chemistry, 1992, vol. 35, # 3, p. 438 - 450
Pyridine, 3-chloro-2-(chloromethyl)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Qingdao Dexin Chemical Co., Ltd | +86-15553333686 | 15553333686@qq.com | China | 3113 | 58 |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10001 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 17714375163 | cfzhang@aikonchem.com | China | 19906 | 55 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 7481 | 58 |
| Hangzhou Milestone Pharmtech Co., Ltd. | 0571-82896630 18969958410 | sales_hz@milestonepharmtech.com | China | 4903 | 55 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 272369594 | 2723695949@qq.com | China | 4995 | 50 |
| Suzhou JingTong Pharmaceutical Co., Ltd. | 13675155016 | tongtf110@sina.com | China | 963 | 55 |
