Acetamide, 2-[2-(1,1-dimethylethyl)phenoxy]-N-(4-hydroxyphenyl)-
- CAS No.
- 831243-31-3
- Chemical Name:
- Acetamide, 2-[2-(1,1-dimethylethyl)phenoxy]-N-(4-hydroxyphenyl)-
- Synonyms
- 2-(2-(tert-Butyl)phenoxy)-N-(4-hydroxyphenyl)acetamide;Acetamide, 2-[2-(1,1-dimethylethyl)phenoxy]-N-(4-hydroxyphenyl)-
- CBNumber:
- CB211442996
- Molecular Formula:
- C18H21NO3
- Molecular Weight:
- 299.36
- MDL Number:
- MOL File:
- 831243-31-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Acetamide, 2-[2-(1,1-dimethylethyl)phenoxy]-N-(4-hydroxyphenyl)- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0434469 | NAT 99.85% | 831243-31-3 | 5mg | $108 | 2026-06-04 | Buy |
| ChemScene | CS-0434469 | NAT 99.85% | 831243-31-3 | 10mg | $173 | 2026-06-04 | Buy |
| ChemScene | CS-0434469 | NAT 99.85% | 831243-31-3 | 25mg | $379 | 2026-06-04 | Buy |
| ChemScene | CS-0434469 | NAT 99.85% | 831243-31-3 | 50mg | $596 | 2026-06-04 | Buy |
| ChemScene | CS-0434469 | NAT 99.85% | 831243-31-3 | 100mg | $921 | 2026-06-04 | Buy |
Acetamide, 2-[2-(1,1-dimethylethyl)phenoxy]-N-(4-hydroxyphenyl)- Chemical Properties, Uses, Production
Uses
NAT is an initial hit of NAMPT activator. NAMPT is the rate-limiting enzyme in the NAD salvage pathway, which makes it an attractive target for the research of many diseases associated with NAD exhaustion such as neurodegenerative diseases[1].
in vivo
NAT (30 mg/kg, ip, every day for 2 weeks) increases the mechanical hyperalgesia threshold, and exhibits neuroprotective effect in chemotherapy-induced peripheral neuropathy (CIPN) mouse model[1].
| Animal Model: | Chemotherapy-induced peripheral neuropathy (CIPN) mouse model[1] |
| Dosage: | 30 mg/kg |
| Administration: | ip, every day for 2 weeks |
| Result: | Increased the mechanical pain threshold of mice, increased the level of NAD in the sciatic nerves. |
References
[1] Wang L, et al. Optimization of NAMPT activators to achieve in vivo neuroprotective efficacy [published online ahead of print, 2022 Mar 16]. Eur J Med Chem. 2022;236:114260. DOI:10.1016/j.ejmech.2022.114260
Acetamide, 2-[2-(1,1-dimethylethyl)phenoxy]-N-(4-hydroxyphenyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
Acetamide, 2-[2-(1,1-dimethylethyl)phenoxy]-N-(4-hydroxyphenyl)- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9780 | 55 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4999 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 9995 | 58 |






