(Undecylthio)-acetic acid
- CAS No.
- 116296-31-2
- Chemical Name:
- (Undecylthio)-acetic acid
- Synonyms
- 3-TDA;3-THIATETRADECANOIC ACID;(Undecylthio)-acetic acid;CZSSKBQAJULWPY-UHFFFAOYSA-N;Acetic acid, 2-(undecylthio)-
- CBNumber:
- CB2114822
- Molecular Formula:
- C13H26O2S
- Molecular Weight:
- 246.41
- MDL Number:
- MFCD01098548
- MOL File:
- 116296-31-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
(Undecylthio)-acetic acid price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 90500 | 3-Thiatetradecanoic Acid ≥98% | 116296-31-2 | 1mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 90500 | 3-Thiatetradecanoic Acid ≥98% | 116296-31-2 | 5mg | $231 | 2026-04-30 | Buy |
| Cayman Chemical | 90500 | 3-Thiatetradecanoic Acid ≥98% | 116296-31-2 | 10mg | $409 | 2026-04-30 | Buy |
| ChemScene | CS-0179236 | 3-Thiatetradecanoic acid ≥98% | 116296-31-2 | 5mg | $552 | 2026-06-04 | Buy |
| ChemScene | CS-0179236 | 3-Thiatetradecanoic acid ≥98% | 116296-31-2 | 10mg | $884 | 2026-06-04 | Buy |
(Undecylthio)-acetic acid Chemical Properties, Uses, Production
Uses
3-Thiatetradecanoic acid is a substrate of N-myristoyltransferase (NMT), which is involved in the metabolism of thiofatty acids[1].
Biological Activity
3-thiatetradecanoic acid is an activator of ppar.the peroxisome proliferator-activated receptors (ppars) are transcription factors involved in fatty acid metabolism and energy homeostasis. the ppars also play crucial roles in the control of cellular growth and differentiation.
in vitro
in bt4cn cells, 3-thiatetradecanoic acid could activate all ppar subtypes dose-dependently. in cell culture experiments, the pparγ-selective ligand brl49653 moderately inhibited growth of bt4cn cells, while administration of 3-thiatetradecanoic acid led to a marked growth inhibition. moreover, the administration of the pparγ-selective antagonist gw9662 abolished brl49653-induced growth inhibition, but only marginally reduced the effect of 3-thiatetradecanoic acid [1].
in vivo
administration of 3-thiatetradecanoic acid increased mitochondrial and peroxisomal beta-oxidative capacity and carnitine palmitoyltransferase activity, but reduced free fatty acid and triacylglycerol levels in plasma compared to palmitic acid-treated rats and controls. 3-thiatetradecanoic acid administration was able to affect the fatty acid composition in plasma and liver by increasing the amount of monoenes [2].
References
1. berge k, tronstad kj, flindt en, rasmussen th, madsen l, kristiansen k, berge rk. tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via ppar-dependent and ppar-independent pathways. carcinogenesis. 2001 nov;22(11):1747-55.2. asiedu, d.k.,froyland, l.,vaagenes, h., et al. long-term effect of tetradecylthioacetic acid: a study on plasma lipid profile and fatty acid composition and oxidation in different rat organs. biochimica et biophysica acta 1300, 86-96 (1996).3. pettersen rj, salem m, skorve j, ulvik rj, berge rk, nordrehaug je. pharmacology and safety of tetradecylthioacetic acid (tta): phase-1 study. j cardiovasc pharmacol. 2008 apr;51(4):410-7.
(Undecylthio)-acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(Undecylthio)-acetic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| Nantong Feiyu Biological Technology CO.,LTD | 0513-68819626 15152877458 | feiyubio@163.com | China | 4807 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 18019219489 18901678489 | tech@zzbioco.com | China | 12062 | 58 |
