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ChemicalBook >> CAS DataBase List >>EC 3.4.21.19

EC 3.4.21.19

EC 3.4.21.19 Structure
EC 3.4.21.19 structure
CAS No.
66676-43-5
Chemical Name:
EC 3.4.21.19
Synonyms
Glu-C;ENDOPROTEINASE GLU-C;PROTEASE V8;V8 PROTEASE;EC 3.4.21.19;Proteinase V8;V8 proteinase;Glu-C, 500 u/mg;V8 endoprotease;proteinase V8 VAN
CBNumber:
CB2117702
Molecular Formula:
NULL
Molecular Weight:
0
MDL Number:
MFCD01324998
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-05-27 23:55:06
Request For Quotation

EC 3.4.21.19 Properties

storage temp. -20°C
form lyophilized powder
color light brown
biological source Staphylococcus aureus (V8)
Water Solubility Soluble in water
Specific Activity 500-1,000units/mg solid
UNSPSC Code 12352204
NACRES NA.54

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H317-H319-H334-H335
Precautionary statements  P280a-P284-P405-P501a-P261-P280-P305+P351+P338-P342+P311
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  36/37/38-42/43
Safety Statements  22-24-26-36/37-45
WGK Germany  3
RTECS  TW0175000
F  10
Storage Class 11 - Combustible Solids
Hazard Classifications Resp. Sens. 1
Skin Sens. 1

EC 3.4.21.19 price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P2922 Endoproteinase Glu-C from Staphylococcus aureus V8 Type XVII-B, lyophilized powder, 500-1,000?units/mg solid 66676-43-5 100units $62.9 2026-04-30 Buy
Sigma-Aldrich P2922 Endoproteinase Glu-C from Staphylococcus aureus V8 Type XVII-B, lyophilized powder, 500-1,000?units/mg solid 66676-43-5 500units $212 2026-04-30 Buy
Sigma-Aldrich P6181 Endoproteinase Glu-C from Staphylococcus aureus V8 suitable for protein sequencing, lyophilized powder 66676-43-5 50μg $263 2026-04-30 Buy
Sigma-Aldrich P2922 Endoproteinase Glu-C from Staphylococcus aureus V8 Type XVII-B, lyophilized powder, 500-1,000?units/mg solid 66676-43-5 2500Units $730 2026-04-30 Buy
Sigma-Aldrich ENDOGLUS-RO Endoproteinase Glu-C Sequencing Grade from Staphylococcus aureus V8 50μg $251 2026-04-30 Buy
Product number Packaging Price Buy
P2922 100units $62.9 Buy
P2922 500units $212 Buy
P6181 50μg $263 Buy
P2922 2500Units $730 Buy
ENDOGLUS-RO 50μg $251 Buy

EC 3.4.21.19 Chemical Properties,Uses,Production

Uses

Endoproteinase Glu-C from Staphylococcus aureus strain V8 is a serine protease used for selective cleavage of proteins for amino acid sequence determination or peptide mapping . Product P2922 has been used to linearize cyclic peptides in C. ternatea leaf extract.

Uses

Endoproteinase Glu-C from Staphylococcus aureus V8 has been used for:

  • obtaining proteolytic cleavage fragments of the S-layer protein (from Bacillus stearothermophilus ATCC 12980) to perform affinity studies.
  • the enzymatic cleavage of native VSTx-3 (voltage sensor toxin 3) peptide for its sequence determination.
  • limited proteolysis of recombinant purified PimA (phosphatidylinositol mannosyltransferase).
  • the digestion of glycosylated hemoglobin for isotope dilution liquid chromatography-tandem mass spectrometry analysis.

Biochem/physiol Actions

Staphylococcus strain V8 protease specifically cleaves peptide bonds on the carboxyl side of aspartic and glutamic acid residues when used in phosphate buffer. When used in ammonium bicarbonate buffer or ammonium acetate buffer cleavage is restricted to the carboxyl side of glutamic acid residues only. The enzyme exhibits maximal activity from pH 4.0 to 7.8. If hemoglobin is used as the substrate, maximal activity is at pH 4.0. The maximal activity is at pH of 7.8 when casein is the substrate.

EC 3.4.21.19 Preparation Products And Raw materials

Raw materials

Preparation Products

EC 3.4.21.19 Suppliers

Global( 120)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Baoman Biotechnology Co., Ltd. 021-62130998 baomanbio@163.com China 199 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
ShangHai YuanYe Biotechnology Co., Ltd. 15026964105 shyysw007@163.com China 4998 60
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Nanjing Dulai Biotechnology Co., Ltd. 025-84699383-8003;025-846993838003-8003 18013301590 njduly@126.com China 3293 55
Shanghai Yaxin Biotechnology Co., Ltd. 021-54336592 zhaozhi@yaxinbio.com China 18 58
Shanghai BeiZhuo Biotech Co., Ltd. 021-61119791,13386096464 bzswkf@foxmail.com China 3916 50
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
Supplier Advantage
Shanghai Baoman Biotechnology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Sichuan Kulinan Technology Co., Ltd 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62
ShangHai YuanYe Biotechnology Co., Ltd. 60
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Nanjing Dulai Biotechnology Co., Ltd. 55
Shanghai Yaxin Biotechnology Co., Ltd. 58
Shanghai BeiZhuo Biotech Co., Ltd. 50
Shanghai Macklin Biochemical Co.,Ltd. 55

View Lastest Price from EC 3.4.21.19 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
EC 3.4.21.19 pictures 2020-01-15 EC 3.4.21.19
66676-43-5
 $1.00 1KG 99.0% 100kg Career Henan Chemical Co

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STAPHYLOCOCCAL SERINE PROTEASE PROTEASE V8 STAPHYLOCOCCAL SERINE PROTEINASE PROTEASE V8 PROTEASE, S AUREUS PROTEASE TYPE XVII-B V8 PROTEASE EC 3.4.21.19 ENDOPROTEINASE GLU-C, STAPHYLOCOCCUS AUREUS Endoproteinase Glu-C, Excision Grade, Staphylococcus aureus Glu-C, 500 u/mg Endoproteinase Glu-C from Staphylococcus aureus V8,V8 Protease ENDOPROTEINASE GLU-C FROM*STAPHYLOCOCCUS AUREUS STR PROTEASE TYPE XVII-B FROM*STAPHYLOCOCCUS AUREUS STR ENDOPROTEINASE GLU-C FROM S. AUREUS STRA IN V8,~800 U/MG EndoproteinaseGluC,Sequencinggrade Endoproteinase Glu-C from Staphylococcus aureus (V8 proteinase), min. 2 U/mg endoproteinase glu-c from staphylococcus aureus v8 Protease tpye ⅩⅤⅢ-B Endoproteinase Glu-C (V8 proteinase), MS approved froM Staphylococcus aureus lyophil. Proteinase V8 proteinase V8 VAN Staphylococcus aureus V8 proteinase V8 endoprotease V8 proteinase PROTEASE from Staphylococcus aureus V8 strain Endoproteinase GluC from Staphylococcus aureus, Recombinant Endoproteinase Glu-C from Staphylococcus aureus V8 Type XVII-B, lyophilized powder, 500-1,000 units/mg solid Protease S V8 Protease Endoprotease Glu-C V8protease Endoproteinase Glu-C Endoproteinase Glu-C, Excision Grade, Staphylococcus aureus Endoproteinase Glu-C from Staphylococcus aureus V8 Endoproteinase Glu-C, recombinant (sequencing grade) ENDOPROTEINASE GLU-C Glu-C Endoproteinase Glu-C，from Staphylococcus aureus strain V8 66676-43-5 Proteases for Cleavage of Proteins Plant Proteomics Plant Biotechnology Enzymatic and Chemical Protein Cleavage Enzymes, Inhibitors, and Substrates Proteomics Proteomics and Protein Expression Proteolytic Enzymes Proteolytic Enzymes and Substrates Protein Identification Protein Digest BioChemical Biochemicals and Reagents enzyme