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ChemicalBook >> CAS DataBase List >>Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]-

Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]-

Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]- Structure
Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]- structure
CAS No.
2128651-12-5
Chemical Name:
Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]-
Synonyms
SIRT5 inhibitor 3;Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]-
CBNumber:
CB211900430
Molecular Formula:
C22H12FN3O4
Molecular Weight:
401.35
MDL Number:
MOL File:
2128651-12-5.mol
Last updated:2025-08-29 17:52:28
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Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]- Properties

Boiling point 700.4±60.0 °C(Predicted)
Density 1.47±0.1 g/cm3(Predicted)
pka 4.09±0.10(Predicted)
form Solid
color Orange to red

Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]- Chemical Properties,Uses,Production

Uses

SIRT5 inhibitor 3 (compound 46) is a potent and competitive SIRT5 inhibitor with an IC50 value of 5.9 μM. SIRT5 inhibitor 3 can inhibit SIRT5 desuccinylation. SIRT5 inhibitor 3 can be used for researching cancer and neurodegenerative diseases[1].

IC 50

SIRT5: 5.9 μM (IC50)

References

[1] Wang Y, et al. Overview of SIRT5 as a potential therapeutic target: Structure, function and inhibitors. Eur J Med Chem. 2022;236:114363. DOI:10.1016/j.ejmech.2022.114363

Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39031 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Nantong Hanfang Biotechnology Co. , Ltd. hanfangpharma@126.com; 18616537568 hanfangpharma@126.com China 29964 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29545 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Nantong Hanfang Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SIRT5 inhibitor 3 pictures 2025-08-29 SIRT5 inhibitor 3
2128651-12-5
 US $52.00 / mg 98.00% 10g TargetMol Chemicals Inc.
Benzoic acid, 4-[5-[(1E)-2-cyano-3-[(4-cyano-3-fluorophenyl)amino]-3-oxo-1-propen-1-yl]-2-furanyl]- SIRT5 inhibitor 3 2128651-12-5 C22H12FN3O4