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H-Leu-Ser-Lys-Leu-NH2

H-Leu-Ser-Lys-Leu-NH2 Structure
H-Leu-Ser-Lys-Leu-NH2 structure
CAS No.
283609-79-0
Chemical Name:
H-Leu-Ser-Lys-Leu-NH2
Synonyms
LSKL;LSKL(a);LSKL-NH2;LSKL, BR;LEU-SER-LYS-LEU-NH2;H-Leu-Ser-Lys-Leu-NH?;H-Leu-Ser-Lys-Leu-NH2;Leu-Ser-Lys-Leu peptide;INHIBITOR OF THROMBOSPONDIN (TSP-1);L-Leucinamide, L-leucyl-L-seryl-L-lysyl-
CBNumber:
CB2125574
Molecular Formula:
C21H42N6O5
Molecular Weight:
458.6
MDL Number:
MFCD03093441
MOL File:
Mol file
TDS File:
TDS
Last updated:2026-09-12 18:50:13
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H-Leu-Ser-Lys-Leu-NH2 Properties

Boiling point 817.8±65.0 °C(Predicted)
Density 1.143±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO : ≥ 100 mg/mL (218.05 mM)
pka 13.40±0.46(Predicted)
form Solid
color White to off-white
Sequence H-Leu-Ser-Lys-Leu-NH2

SAFETY

Risk and Safety Statements

WGK Germany  3

H-Leu-Ser-Lys-Leu-NH2 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FL109362 H-Leu-Ser-Lys-Leu-NH2 trifluoroacetate salt 283609-79-0 250mg $900 2026-06-04 Buy
Biosynth FL109362 H-Leu-Ser-Lys-Leu-NH2 trifluoroacetate salt 283609-79-0 100mg $900 2026-06-04 Buy
Biosynth FL109362 H-Leu-Ser-Lys-Leu-NH2 trifluoroacetate salt 283609-79-0 50mg $900 2026-06-04 Buy
Biosynth FL109362 H-Leu-Ser-Lys-Leu-NH2 trifluoroacetate salt 283609-79-0 500mg $1205 2026-06-04 Buy
Biosynth FL109362 H-Leu-Ser-Lys-Leu-NH2 trifluoroacetate salt 283609-79-0 1000mg $2100 2026-06-04 Buy
Product number Packaging Price Buy
FL109362 250mg $900 Buy
FL109362 100mg $900 Buy
FL109362 50mg $900 Buy
FL109362 500mg $1205 Buy
FL109362 1000mg $2100 Buy

H-Leu-Ser-Lys-Leu-NH2 Chemical Properties, Uses, Production

Uses

L-Leucyl-L-seryl-L-lysyl-L-leucinamide can be useful in the study of relative contributions of core protein and solvation shell in terahertz dielectric properties of protein solutions.

in vivo

LSKL, Inhibitor of Thrombospondin (TSP-1) (1 mg/kg; intraperitoneal injection; male Sprague-Dawley rats) is protective against subarachnoid fibrosis, attenuates ventriculomegaly and effectively suppresses hydrocephalus. LSKL, Inhibitor of Thrombospondin (TSP-1) treatment inhibits TGF-β1 activity and subsequent Smad2/3 signaling[1].
LSKL, Inhibitor of Thrombospondin (TSP-1) (30 mg/kg, i.p.) successfully inhibits transforming growth factor (TGF) β-Smad signal activation induced by partial hepatectomy. LSKL, Inhibitor of Thrombospondin (TSP-1) successfully attenuates TGF-β-Smad signal activation by antagonizing TSP-1, but not by reducing TSP-1 protein expression. LSKL, Inhibitor of Thrombospondin (TSP-1) accelerates hepatocyte proliferation after hepatectomy[3].

Animal Model:103 male Sprague-Dawley rats (6 weeks of age; 160-180 g) with subarachnoid hemorrhage (SAH)[1]
Dosage:1 mg/kg
Administration:Intraperitoneal injection
Result:Was protective against subarachnoid fibrosis, attenuated ventriculomegaly and effectively suppressed hydrocephalus.

H-Leu-Ser-Lys-Leu-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

H-Leu-Ser-Lys-Leu-NH2 Suppliers

Global Suppliers ( 69)
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Nanjing Dulai Biotechnology Co., Ltd. 025-84699383-8003;025-846993838003-8003 18013301590 njduly@126.com China 3293 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Creative Peptides info@creative-peptides.com United States 6083 56
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55
Chengdu Youngshe Chemical Co., Ltd. +86-17380623303 Caroline@youngshechem.com China 4725 58
Supplier Advantage
GL Biochem (Shanghai) Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60
Nanjing Dulai Biotechnology Co., Ltd. 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Creative Peptides 56
Shanghai YuanYe Biotechnology Co., Ltd. 60
Nanjing Leon Biological Technology Co., Ltd. 55
Nanjing Peptide Biotech Ltd. 55
Chengdu Youngshe Chemical Co., Ltd. 58

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INHIBITOR OF THROMBOSPONDIN (TSP-1) LEU-SER-LYS-LEU-NH2 LSKL LSKL-NH2 Leu-Ser-Lys-Leu peptide LSKL, BR H-Leu-Ser-Lys-Leu-NH? LSKL(a) L-Leucinamide, L-leucyl-L-seryl-L-lysyl- (S)-6-amino-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)-2-((S)-2-((S)-2-amino-4-methylpentanamido)-3-hydroxypropanamido)hexanamide H-Leu-Ser-Lys-Leu-NH2 trifluoroacetate salt Thrombospondin (TSP-1) Inhibitor, LSKL - 1 mg Thrombospondin (TSP-1) Inhibitor scrambled peptide, SLLK - 1 mg H-Leu-Ser-Lys-Leu-NH2 283609-79-0 C21H42N6O5 Peptides Other Peptides Amino Acids and Peptides BioChemical Biochemicals and Reagents peptide Other Peptides Peptides and Proteins Peptides for Cell Biology