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Cyclo(-Arg-Gly-Asp-D-Tyr-Lys)

CAS No.
217099-14-4
Chemical Name:
Cyclo(-Arg-Gly-Asp-D-Tyr-Lys)
Synonyms
CYCLO(-RGDYK);Cyclo (-RGDyK) - 5 mg;c(RGDyK),Cyclo(RGDyK);cyclo (Arg-Gly-Asp-Tyr-Lys);Cyclo(-Arg-Gly-Asp-D-Tyr-Lys);Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt;Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl);2-((2S,5R,8S,11S)-8-(4-Aminobutyl)-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid
CBNumber:
CB8205029
Molecular Formula:
C27H41N9O8
Molecular Weight:
619.68
MDL Number:
MFCD08459533
MOL File:
217099-14-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:25

Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) Properties

Density 1.52±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 4.01±0.10(Predicted)
form Solid
color White to off-white
Sequence Cyclo(Arg-Gly-Asp-{d-Tyr}-Lys)
InChIKey LAROZEWEPNAWMD-OFICADHYNA-N
SMILES C(C1C=CC(=CC=1)O)[C@H]1NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC1=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CC(=O)O)=O |&1:8,11,17,20,r|

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth PCI-3662-PI Cyclo(Arg-Gly-Asp-D-Tyr-Lys) 217099-14-4 1mg $150 2026-06-04 Buy
Biosynth PCI-3662-PI Cyclo(Arg-Gly-Asp-D-Tyr-Lys) 217099-14-4 5mg $263.9 2026-06-04 Buy
Biosynth PCI-3662-PI Cyclo(Arg-Gly-Asp-D-Tyr-Lys) 217099-14-4 25mg $1050.75 2026-06-04 Buy
Biosynth FC110223 Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt 217099-14-4 1mg $174.15 2026-06-04 Buy
Biosynth FC110223 Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt 217099-14-4 2mg $261.24 2026-06-04 Buy
Product number Packaging Price Buy
PCI-3662-PI 1mg $150 Buy
PCI-3662-PI 5mg $263.9 Buy
PCI-3662-PI 25mg $1050.75 Buy
FC110223 1mg $174.15 Buy
FC110223 2mg $261.24 Buy

Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) Chemical Properties, Uses, Production

Uses

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

IC 50

αvβ3: 20 nM (IC50)

References

[1] Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36. PMID:11216533

Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 100)
Supplier Tel Email Country ProdList Advantage
Shanghai HongTide Biotechnology Co.,Ltd. 15318089928 alex@hanhonggroup.com China 4604 58
YantaiBio 13758194781; 13758194781 764619768@qq.com China 1755 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Creative Peptides info@creative-peptides.com United States 6083 56
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Alabiotech Inc. 001-619-354-5251 sales@alabiotech-e.com United States 972 60
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55

View Latest Price from Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CYCLO(-ARG-GLY-ASP-D-TYR-LYS) pictures 2026-07-01 CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
217099-14-4
1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
CYCLO(-RGDYK) cyclo (Arg-Gly-Asp-Tyr-Lys) Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl) c(RGDyK),Cyclo(RGDyK) 2-((2S,5R,8S,11S)-8-(4-Aminobutyl)-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid Cyclo (-RGDyK) - 5 mg Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) 217099-14-4 peptide