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ChemicalBook >> CAS DataBase List >>4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro-

4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro-

4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro- Structure
4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro- structure
CAS No.
2498762-42-6
Chemical Name:
4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro-
Synonyms
Antitubercular agent-32;4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro-
CBNumber:
CB212721096
Molecular Formula:
C22H28N4O5S2
Molecular Weight:
492.61
MDL Number:
MOL File:
2498762-42-6.mol
MSDS File:
SDS
Last updated:2026-05-11 15:21:01
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4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro- Properties

Boiling point 711.6±70.0 °C(Predicted)
Density 1.57±0.1 g/cm3(Predicted)
pka 7.19±0.20(Predicted)

4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro- Chemical Properties, Uses, Production

Uses

Antitubercular agent-32 is a derivate of Benzothiazinone (HY-13579A), inhibits M. tuberculosis, and shows improved metabolic stability and enhanced water solubility. Antitubercular agent-32 exerts antitubercular effect by targeting decaprenylphosphoryl-β-D-ribose 2’-oxidase (DprE1, IC50=3.9 μM)[1].

References

[1] Shi R, et al. Development of 6-Methanesulfonyl-8-nitrobenzothiazinone Based Antitubercular Agents. ACS Med Chem Lett. 2022 Mar 10;13(4):593-598. DOI:10.1021/acsmedchemlett.1c00652

4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro- Preparation Products And Raw materials

Raw materials

Preparation Products

4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Antitubercular agent-32 pictures 2026-05-11 Antitubercular agent-32
2498762-42-6
 $2140.00-3520.00 10g TargetMol Chemicals Inc.

2498762-42-6 (4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro-) Related Search:

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4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]oct-7-yl]-6-(methylsulfonyl)-8-nitro- Antitubercular agent-32 2498762-42-6