quinolinic acid, 2-methyl ester
- CAS No.
- 24195-07-1
- Chemical Name:
- quinolinic acid, 2-methyl ester
- Synonyms
- 2-(methoxycarbonyl)nicotinic acid;QA2ME;2-Methyl quinolinate;2-carbomethoxynicotinic acid;quinolinic acid, 2-methyl ester;2-methoxycarbonyl-3-pyridinecarboxylic acid;2-Methoxycarbonylpyridine-3-carboxylic acid;2,3-Pyridinedicarboxylic acid, 2-methyl ester
- CBNumber:
- CB21334528
- Molecular Formula:
- C8H7NO4
- Molecular Weight:
- 181.15
- MDL Number:
- MFCD00111560
- MOL File:
- 24195-07-1.mol
- MSDS File:
- SDS
| Melting point | 54-55 °C |
|---|---|
| Boiling point | 380.7±27.0 °C(Predicted) |
| Density | 1.361±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 2.59±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C8H7NO4/c1-13-8(12)6-5(7(10)11)3-2-4-9-6/h2-4H,1H3,(H,10,11) |
| InChIKey | OSSIORZYXTUXBL-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)=NC=CC=C1C(O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
quinolinic acid, 2-methyl ester price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR901680 | 2-(Methoxycarbonyl)nicotinic acid 96% | 24195-07-1 | 100mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR901680 | 2-(Methoxycarbonyl)nicotinic acid 96% | 24195-07-1 | 250mg | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR901680 | 2-(Methoxycarbonyl)nicotinic acid 96% | 24195-07-1 | 1g | $62 | 2026-06-04 | Buy |
| Apolloscientific | OR901680 | 2-(Methoxycarbonyl)nicotinic acid 96% | 24195-07-1 | 5g | $282 | 2026-06-04 | Buy |
| Apolloscientific | OR901680 | 2-(Methoxycarbonyl)nicotinic acid 96% | 24195-07-1 | 25g | $955 | 2026-06-04 | Buy |
quinolinic acid, 2-methyl ester Chemical Properties, Uses, Production
Synthesis
67-56-1
699-98-9
24195-07-1
General procedure for the synthesis of methyl 3-carboxylic acid pyridine-2-carboxylate from methanol and 2,3-pyridinedicarboxylic anhydride: 2,3-pyridinedicarboxylic anhydride (5.0 g, 34 mmol) was dissolved in methanol (25 mL). The reaction mixture was heated to reflux for 2 hours and the solvent was subsequently removed by rotary evaporation. The resulting white solid was dissolved in ethyl acetate (25 mL) under reflux conditions and the insoluble by-products were removed by filtration. The filtrate was concentrated under reduced pressure and recrystallized from ethyl acetate to give the final methyl 3-carboxypyridine-2-carboxylate (4.5 g, 71% yield) as a white solid with a melting point of 157-159 °C.1H NMR (300 MHz, CDCl3) δ 8.84 (dd, J=1.7,5.0 Hz, 1H), 8.34 (dd, J=1.6, 7.9 Hz, 1H), 7.57 (dd, J=5.0,8.1 Hz, 1H), 4.00 (s, 3H).
References
[1] Angewandte Chemie - International Edition, 2011, vol. 50, # 22, p. 5192 - 5196
[2] Synlett, 2006, # 12, p. 1938 - 1942
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 8, p. 3840 - 3853
[4] Patent: WO2017/160898, 2017, A1. Location in patent: Paragraph 00107; 00136
[5] Journal of Medicinal Chemistry, 2006, vol. 49, # 15, p. 4544 - 4567
quinolinic acid, 2-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijiazhuang Jing Kang Technology Co.Ltd. | 13933818572 | 1519554262@qq.com | China | 1785 | 58 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3539 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from quinolinic acid, 2-methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-08 | quinolinic acid, 2-methyl ester
24195-07-1
|
$1.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- quinolinic acid, 2-methyl ester
24195-07-1
- $1.00
- 98%
- Career Henan Chemical Co
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