sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
- CAS No.
- 119515-38-7
- Chemical Name:
- sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
- Synonyms
- Picaridin;ICARIDIN;HYDROXYETHYL ISOBUTYL PIPERIDINE CARBOXYLATE;Bayrepel;lcaridin;Icaridine;Bayrepe;KBR 3023;Icardine;ICARIDINA
- CBNumber:
- CB2136802
- Molecular Formula:
- C12H23NO3
- Molecular Weight:
- 229.32
- MDL Number:
- MFCD01756488
- MOL File:
- 119515-38-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | <-170° |
|---|---|
| Boiling point | 2800C |
| Density | d20 1.07 |
| refractive index | nD20 1.4717 |
| Flash point | 142°C |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| pka | 15.15±0.10(Predicted) |
| color | Colourless |
| Henry's Law Constant | 3.3×105 mol/(m3Pa) at 25℃, HSDB (2015) |
| Cosmetics Ingredients Functions | ANTIMICROBIAL |
| InChI | InChI=1S/C12H23NO3/c1-3-10(2)16-12(15)13-8-5-4-6-11(13)7-9-14/h10-11,14H,3-9H2,1-2H3 |
| InChIKey | QLHULAHOXSSASE-UHFFFAOYSA-N |
| SMILES | N1(C(OC(C)CC)=O)CCCCC1CCO |
| CAS DataBase Reference | 119515-38-7 |
| EWG's Food Scores | 1 |
| FDA UNII | N51GQX0837 |
| Pesticides Freedom of Information Act (FOIA) | Picaridin |
| EPA Substance Registry System | Icaridin (119515-38-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazardous Substances Data | 119515-38-7(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 in rats (mg/kg): 4743 orally; >2000 dermally (Yap); LC50 in rainbow trout (96 hr): 173 mg/l; in bobwhite quail (5 day diet): >5000 ppm a.i. in diet (WHO). | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | I1210 | Picaridin min. 98.0 %(total of isomers) | 119515-38-7 | 5G | $58 | 2026-04-30 | Buy |
| TCI Chemical | I1210 | Picaridin min. 98.0 %(total of isomers) | 119515-38-7 | 25G | $174 | 2026-04-30 | Buy |
| Cayman Chemical | 16458 | Picaridin ≥95% | 119515-38-7 | 1g | $83 | 2026-04-30 | Buy |
| Cayman Chemical | 16458 | Picaridin ≥95% | 119515-38-7 | 5g | $330 | 2026-04-30 | Buy |
| Usbiological | 019691 | Picaridin | 119515-38-7 | 100g | $531 | 2026-06-03 | Buy |
sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate Chemical Properties, Uses, Production
Description
Picaridin is an insect repellent. It inhibits A. aegypti odorant receptor 2 (AaOR2) or AaOR8 in the presence of their odorant activators, indole and octenol, respectively, expressed in Xenopus oocytes (IC50s = 1,452 and 1,911 μM, respectively). Picaridin reduces the number of entries into a food chamber by female D. melanogaster in an olfactory-based choice assay. It acts synergistically with the non-pyrethroid insecticide pyrimiphos methyl to increase mortality of A. gambiae and reduce blood feeding when used at a concentration of 10 g/m2 on nets surrounding guinea pig cages. Formulations containing picaridin have been used as insect repellents against flies, mosquitoes, chiggers, ticks, and fleas.
Chemical Properties
Colorless Liquid
Uses
Insect repellent.
Uses
Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources.Insect repellent.
Production Methods
Commercial production of icaridin involves a highly optimised chemical synthesis process developed to meet global demand for safe and effective insect repellents. The active ingredient is a piperidine derivative, and its synthesis typically starts with cyclohexane derivatives, which undergo a series of reactions including chlorination, etherification, and nitrile formation to build the final molecular structure.
Definition
ChEBI: Butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate is a carboxylic acid and a member of piperidines.
Hazard
A reproductive hazard.
Mechanism of action
Topically applied, repellent. Odorant receptor. It has been proposed that icaridin may bind to odorant binding protein 1 (AgamOBP1).
References
[1] JONATHAN D BOHBOT Joseph C D. Insect repellents: modulators of mosquito odorant receptor activity.[J]. PLoS ONE, 2010: e12138. DOI: 10.1371/journal.pone.0012138
[2] ZAINULABEUDDIN SYED. Generic insect repellent detector from the fruit fly Drosophila melanogaster.[J]. PLoS ONE, 2011: e17705. DOI: 10.1371/journal.pone.0017705
[3] CéDRIC PENNETIER. Synergy between repellents and non-pyrethroid insecticides strongly extends the efficacy of treated nets against Anopheles gambiae.[J]. ACS Applied Bio Materials, 2007: 38. DOI: 10.1186/1475-2875-6-38
Pesticide Type
Insecticide; Repellent; Veterinary substance
sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuyang Sineva Pharmaceutical Co., Ltd | 13866224493 | dingzhikui@sineva.com.cn | China | 27 | 58 |
| Hubei XinghengKang Chemical Technology Co., Ltd. | 027-88878869 18162384755 | xhkhu2014@163.com | China | 240 | 58 |
| Hubei Langbowan Biopharmaceutical Co., Ltd | 18086032675 | 3831791620@qq.com | China | 1887 | 58 |
| Shenzhen Xingkaiyue Biotechnology Co. , Ltd. | 0755-18589069862 18589069862 | 1158168052@qq.com | China | 1000 | 58 |
| Shandong Suihua Biotechnology Co., Ltd. | 15169101773 15169101773 | 519904247@qq.com | China | 1077 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
View Latest Price from sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-15 | sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
119515-38-7
|
1kg | 97.8% | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-21 | sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
119515-38-7
|
$102.00-110.00 | 1Tons | 99.99% | 100Tons | Hebei Dangtong Import and export Co LTD | |
 |
2026-07-17 | Picaridin
119515-38-7
|
$31.00 | 99.93% | 10g | TargetMol Chemicals Inc. |
-
- sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
119515-38-7
- 97.8%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
119515-38-7
- $102.00-110.00
- 99.99%
- Hebei Dangtong Import and export Co LTD
-
- Picaridin
119515-38-7
- $31.00
- 99.93%
- TargetMol Chemicals Inc.
