MK 996
- CAS No.
- 157263-00-8
- Chemical Name:
- MK 996
- Synonyms
- MK 996;L-159282;3-((2'-(Benzoylaminosulfonyl)biphenyl-4-yl)methyl)-2-ethyl-5,7-dimethyl-3H-imidazo(4,5-B)pyridine;Benzamide, N-[[4'-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl][1,1'-biphenyl]-2-yl]sulfonyl]-
- CBNumber:
- CB21389124
- Molecular Formula:
- C30H28N4O3S
- Molecular Weight:
- 524.63
- MDL Number:
- MFCD00922104
- MOL File:
- 157263-00-8.mol
- MSDS File:
- SDS
MK 996 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | HGA26300 | 3-((2'-(Benzoylaminosulfonyl)biphenyl-4-yl)methyl)-2-ethyl-5,7-dimethyl-3H-imidazo(4,5-B)pyridine | 157263-00-8 | 1mg | $1370.69 | 2026-06-04 | Buy |
| Biosynth | HGA26300 | 3-((2'-(Benzoylaminosulfonyl)biphenyl-4-yl)methyl)-2-ethyl-5,7-dimethyl-3H-imidazo(4,5-B)pyridine | 157263-00-8 | 5mg | $4454.75 | 2026-06-04 | Buy |
| Biosynth | HGA26300 | 3-((2'-(Benzoylaminosulfonyl)biphenyl-4-yl)methyl)-2-ethyl-5,7-dimethyl-3H-imidazo(4,5-B)pyridine | 157263-00-8 | 10mg | $7127.6 | 2026-06-04 | Buy |
| Biosynth | HGA26300 | 3-((2'-(Benzoylaminosulfonyl)biphenyl-4-yl)methyl)-2-ethyl-5,7-dimethyl-3H-imidazo(4,5-B)pyridine | 157263-00-8 | 25mg | $13364 | 2026-06-04 | Buy |
| Biosynth | HGA26300 | 3-((2'-(Benzoylaminosulfonyl)biphenyl-4-yl)methyl)-2-ethyl-5,7-dimethyl-3H-imidazo(4,5-B)pyridine | 157263-00-8 | 50mg | $21383 | 2026-06-04 | Buy |
MK 996 Chemical Properties, Uses, Production
Uses
L-159282 is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity.
in vivo
In the anesthetized chimpanzee, L-159282 (1 mg/kg, iv) produces 100% inhibition of the AII pressor response and is still active (52%) at 24 h. In aortic coarcted (high renin) rats, L-159282 (3 mg/kg, p.o.) reduces blood pressure to normotensive (< 120 mm Hg) levels without reflex tachycardia. This dose of L-159282 reduces blood pressure to approximately the same level as both losartan (3 mg/kg, p.o.) and enalapril (3 mg/kg, p.o.) in this model[1].
References
[1] Kivlighn SD, et al. In vivo pharmacology of a novel AT1 selective angiotensin II receptor antagonist, MK-996. Am J Hypertens. 1995 Jan;8(1):58-66. DOI:10.1016/0895-7061(94)00169-c
MK 996 Preparation Products And Raw materials
Raw materials
Preparation Products
MK 996 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q | meishipharma@126.com | China | 20027 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
