Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine

3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine

3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine Structure
3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine structure
CAS No.
151227-58-6
Chemical Name:
3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine
Synonyms
AP-521 (Free base);AP 521 (Free base),AP521 (Free base);3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine;[1]Benzothieno[2,3-c]pyridine-3-carboxamide, N-(1,3-benzodioxol-5-ylmethyl)-1,2,3,4-tetrahydro-, (3R)-
CBNumber:
CB21391439
Molecular Formula:
C20H18N2O3S
Molecular Weight:
366.44
MDL Number:
MFCD31567470
MOL File:
151227-58-6.mol
MSDS File:
SDS
Last updated:2026-08-05 19:35:02
Request For Quotation

3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine Properties

Boiling point 654.735±55.00 °C(Press: 760.00 Torr)(predicted)
Density 1.368±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 14.470±0.20(predicted)
FDA UNII PP22EB9LAB

3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine Chemical Properties, Uses, Production

Uses

AP-521 (free base) is a benzothienopyridine derivative that exhibits potent anxiolytic effects by acting as a postsynaptic 5-HT1A receptor agonist and by enhancing serotonergic neural transmission in the medial prefrontal cortex (mPFC). AP-521 (free base) is promising for research of anxiety disorders[1].

References

[1] Kasahara K, et al. The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats. J Pharmacol Sci. 2015 Jan;127(1):109-16. DOI:10.1016/j.jphs.2014.11.008

3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AP-521 Free base pictures 2026-08-15 AP-521 Free base
151227-58-6
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
3-((benzodioxol-5-yl)methylaminocarbonyl)-1,2,3,4-tetrahydro(1)benzothieno(2.3-c)pyridine [1]Benzothieno[2,3-c]pyridine-3-carboxamide, N-(1,3-benzodioxol-5-ylmethyl)-1,2,3,4-tetrahydro-, (3R)- AP-521 (Free base) AP 521 (Free base),AP521 (Free base) 151227-58-6