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GPX4-IN-13

GPX4-IN-13 Structure
GPX4-IN-13 structure
CAS No.
2644044-43-7
Chemical Name:
GPX4-IN-13
Synonyms
GPX4-IN-13;Benzonitrile, 4-[(2E)-3-[2-(2-formylphenoxy)phenyl]-1-oxo-2-propen-1-yl]-
CBNumber:
CB214736908
Molecular Formula:
C23H15NO3
Molecular Weight:
353.37
MDL Number:
MOL File:
2644044-43-7.mol
MSDS File:
SDS
Last updated:2025-08-21 14:05:29
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GPX4-IN-13 Properties

Boiling point 547.854±50.00 °C(Press: 760.00 Torr)(predicted)
Density 1.274±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility DMSO: Sparingly soluble: 1-10 mg/ml

GPX4-IN-13 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 40498 GPX4 16 ≥98% 2644044-43-7 1mg $74 2026-04-30 Buy
Cayman Chemical 40498 GPX4 16 ≥98% 2644044-43-7 5mg $314 2026-04-30 Buy
Cayman Chemical 40498 GPX4 16 ≥98% 2644044-43-7 10mg $590 2026-04-30 Buy
ChemScene CS-1184933 GPX4-IN-13 2644044-43-7 1mg $159 2026-06-04 Buy
ChemScene CS-1184933 GPX4-IN-13 2644044-43-7 5mg $679 2026-06-04 Buy
Product number Packaging Price Buy
40498 1mg $74 Buy
40498 5mg $314 Buy
40498 10mg $590 Buy
CS-1184933 1mg $159 Buy
CS-1184933 5mg $679 Buy

GPX4-IN-13 Chemical Properties, Uses, Production

Uses

GPX4-IN-13 (compound 16) is a GPX4 inhibitor with anticancer activity. GPX4-IN-13 reduces thyroid cell proliferation and induces ferroptosis by inhibiting the expression level of GPX4. GPX4-IN-13 inhibits the growth of three thyroid cancer cell lines: N-thy-ori-3-1 (IC50=8.39 μM), MDA-T32 (IC50=10.28 μM) and MDA-T41 (IC50=8.18 μM)[1].

References

[1] Pamarthy, et al. "Diaryl ether derivative inhibits GPX4 expression levels to induce ferroptosis in thyroid cancer cells." Drug Development Research 84.5 (2023): 861-887. DOI:10.1002/ddr.22059

GPX4-IN-13 Preparation Products And Raw materials

Raw materials

Preparation Products

GPX4-IN-13 Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4999 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

2644044-43-7 (GPX4-IN-13) Related Search:

GPX4-IN-6 L-Buthionine-(S,R)-sulfoximine methyl (1S,3R)-2-(2-chloroacetyl)-1-(4-methylsulfonylphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate GPX4 Inhibitor 17 Sulfasalazine
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GPX4-IN-13 Benzonitrile, 4-[(2E)-3-[2-(2-formylphenoxy)phenyl]-1-oxo-2-propen-1-yl]- 2644044-43-7