6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE
- CAS No.
- 59611-52-8
- Chemical Name:
- 6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE
- Synonyms
- 6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE;Quinoline, 6-fluoro-1,2,3,4-tetrahydro-;6-Fluoro-1,2,3,4-tetrahydroquinoline,97%
- CBNumber:
- CB21495087
- Molecular Formula:
- C9H10FN
- Molecular Weight:
- 151.18
- MDL Number:
- MFCD09040997
- MOL File:
- 59611-52-8.mol
| Product description | Number | Pack Size | Price |
| 6-fluoro-1,2,3,4-tetrahydroquinoline | B440065 | 100mg | $65 |
| 6-Fluoro-1,2,3,4-tetrahydroquinoline | 8873AB | 250mg | $81 |
| 6-Fluoro-1,2,3,4-tetrahydroquinoline 99.79% | CS-W007199 | 250mg | $46 |
| 6-Fluoro-1,2,3,4-tetrahydroquinoline 97% | P000378886 | 250mg | $59 |
| 6-Fluoro-1,2,3,4-tetrahydroquinoline | PC52113 | 1g | $280 |
| More product size | |||
| Melting point | 32-34℃ |
|---|---|
| Boiling point | 248.0±29.0 °C(Predicted) |
| Density | 1.107±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 5.15±0.20(Predicted) |
| Appearance | Off-white to light brown <32°C Solid,>34°C Liquid |
| CAS DataBase Reference | 59611-52-8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 45 | |||||||||
| HS Code | 2933499090 | |||||||||
| NFPA 704 |
|
6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B440065 | 6-fluoro-1,2,3,4-tetrahydroquinoline | 59611-52-8 | 100mg | $65 | 2021-12-16 | Buy |
| AK Scientific | 8873AB | 6-Fluoro-1,2,3,4-tetrahydroquinoline | 59611-52-8 | 250mg | $81 | 2021-12-16 | Buy |
| ChemScene | CS-W007199 | 6-Fluoro-1,2,3,4-tetrahydroquinoline 99.79% | 59611-52-8 | 250mg | $46 | 2021-12-16 | Buy |
| Ark Pharm | P000378886 | 6-Fluoro-1,2,3,4-tetrahydroquinoline 97% | 59611-52-8 | 250mg | $59 | 2021-12-16 | Buy |
| Apolloscientific | PC52113 | 6-Fluoro-1,2,3,4-tetrahydroquinoline | 59611-52-8 | 1g | $280 | 2021-12-16 | Buy |
6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE Chemical Properties,Uses,Production
Uses
6-Fluoro-1,2,3,4-tetrahydroquinoline is used as pharmaceutical intermediate.
Synthesis
75893-82-2
59611-52-8
A THF solution of 6-fluoro-3,4-dihydroquinolin-2(1H)-one (6.0 g, 36.36 mmol) was slowly added to a THF (80 mL) suspension of LiAlH4 (2.76 g, 72.73 mmol) under stirring conditions. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was quenched with saturated sodium chloride solution and ethyl acetate and filtered through diatomaceous earth. The filtrate was diluted with ethyl acetate and washed sequentially with water and saturated sodium chloride solution and the organic phase was dried with anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give 4.5 g (81% yield) of 6-fluoro-1,2,3,4-tetrahydroquinoline as a brown liquid.1H NMR (400 MHz, CDCl3): δ 6.65-6.78 (m, 2H), 6.37-6.40 (m, 1H), 3.26 (t, J=5.3 Hz, 2H), 2.73 (t, J=6.6 Hz, 2H), 1.88-1.94 (m, 2H).
References
[1] Patent: WO2017/142883, 2017, A1. Location in patent: Paragraph 0183; 0186
[2] Patent: WO2014/78813, 2014, A1. Location in patent: Page/Page column 141
6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39002 | 58 |
View Lastest Price from 6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-08 | 6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE
59611-52-8
|
US $5.50 / KG | 1KG | 98%-99% | 1kg-100kg | Career Henan Chemical Co |
-
- 6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE
59611-52-8
- US $5.50 / KG
- 98%-99%
- Career Henan Chemical Co
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