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ChemicalBook >> CAS DataBase List >>6-Fluoro-1,2,3,4-tetrahydroquinoline

6-Fluoro-1,2,3,4-tetrahydroquinoline

6-Fluoro-1,2,3,4-tetrahydroquinoline Structure
6-Fluoro-1,2,3,4-tetrahydroquinoline structure
CAS No.
59611-52-8
Chemical Name:
6-Fluoro-1,2,3,4-tetrahydroquinoline
Synonyms
6-Fluoro-1,2,3,4-tetrahydroquinoline;Quinoline, 6-fluoro-1,2,3,4-tetrahydro-;6-Fluoro-1,2,3,4-tetrahydroquinoline,97%
CBNumber:
CB21495087
Molecular Formula:
C9H10FN
Molecular Weight:
151.18
MDL Number:
MFCD09040997
MOL File:
59611-52-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:16
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6-Fluoro-1,2,3,4-tetrahydroquinoline Properties

Melting point 32-34℃
Boiling point 248.0±29.0 °C(Predicted)
Density 1.107±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 5.15±0.20(Predicted)
Appearance Off-white to light brown <32°C Solid,>34°C Liquid
CAS DataBase Reference 59611-52-8

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  T
Risk Statements  25
Safety Statements  45
HS Code  2933499090
NFPA 704
1
2 0

6-Fluoro-1,2,3,4-tetrahydroquinoline price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC52113 6-Fluoro-1,2,3,4-tetrahydroquinoline >98% 59611-52-8 1g $21 2026-06-04 Buy
Apolloscientific PC52113 6-Fluoro-1,2,3,4-tetrahydroquinoline >98% 59611-52-8 5g $63 2026-06-04 Buy
Apolloscientific PC52113 6-Fluoro-1,2,3,4-tetrahydroquinoline >98% 59611-52-8 25g $312 2026-06-04 Buy
Apolloscientific PC52113 6-Fluoro-1,2,3,4-tetrahydroquinoline >98% 59611-52-8 100g $1235 2026-06-04 Buy
Synthonix F38792 6-Fluoro-1,2,3,4-tetrahydroquinoline 95+% 59611-52-8 100mg $18 2026-05-06 Buy
Product number Packaging Price Buy
PC52113 1g $21 Buy
PC52113 5g $63 Buy
PC52113 25g $312 Buy
PC52113 100g $1235 Buy
F38792 100mg $18 Buy

6-Fluoro-1,2,3,4-tetrahydroquinoline Chemical Properties,Uses,Production

Uses

6-Fluoro-1,2,3,4-tetrahydroquinoline is used as pharmaceutical intermediate.

Synthesis

6-FLUORO-3,4-DIHYDROQUINOLIN-2(1H)-ONE

75893-82-2

6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE

59611-52-8

A THF solution of 6-fluoro-3,4-dihydroquinolin-2(1H)-one (6.0 g, 36.36 mmol) was slowly added to a THF (80 mL) suspension of LiAlH4 (2.76 g, 72.73 mmol) under stirring conditions. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was quenched with saturated sodium chloride solution and ethyl acetate and filtered through diatomaceous earth. The filtrate was diluted with ethyl acetate and washed sequentially with water and saturated sodium chloride solution and the organic phase was dried with anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give 4.5 g (81% yield) of 6-fluoro-1,2,3,4-tetrahydroquinoline as a brown liquid.1H NMR (400 MHz, CDCl3): δ 6.65-6.78 (m, 2H), 6.37-6.40 (m, 1H), 3.26 (t, J=5.3 Hz, 2H), 2.73 (t, J=6.6 Hz, 2H), 1.88-1.94 (m, 2H).

References

[1] Patent: WO2017/142883, 2017, A1. Location in patent: Paragraph 0183; 0186
[2] Patent: WO2014/78813, 2014, A1. Location in patent: Page/Page column 141

6-Fluoro-1,2,3,4-tetrahydroquinoline Preparation Products And Raw materials

Raw materials

6-Fluoro-3,4-dihydroquinolin-2(1H)-one 6-Fluoroquinoline Lithium Aluminum Hydride Tetrahydrofuran

Preparation Products

6-Fluoro-1,2,3,4-tetrahydroquinoline Suppliers

Global( 83)Suppliers
Supplier Tel Email Country ProdList Advantage
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Shanghai Keepontech Co.,Ltd 021-54849683 13601642561 sales@keepontech.com China 997 59
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Shijiazhuang Lickon PharmaTech Co., Ltd. 031185291771 13832391721 yaofeng2005@163.com China 947 58
Shanghai Chainpharm Bio-medical Technology Co., Ltd. +86-021-61727342 13611721451 sales@chainpharm.com China 984 58
HBCChem, Inc. +1-510-219-6317 sales@hbcchem.com United States 10628 60
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4538 58
Supplier Advantage
PharmaBlock Sciences (Nanjing),Inc. 55
Alfa Aesar 84
Shanghai Keepontech Co.,Ltd 59
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Shanghai Raise Chemical Technology Co.,Ltd 55
Shijiazhuang Lickon PharmaTech Co., Ltd. 58
Shanghai Chainpharm Bio-medical Technology Co., Ltd. 58
HBCChem, Inc. 60
Bide Pharmatech Ltd. 60
Mashilabs (Shanghai) Co.,Ltd. 58

View Lastest Price from 6-Fluoro-1,2,3,4-tetrahydroquinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE pictures 2020-01-08 6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE
59611-52-8
 $5.50 1KG 98%-99% 1kg-100kg Career Henan Chemical Co

6-Fluoro-1,2,3,4-tetrahydroquinoline Spectrum

6-FLUORO-1,2,3,4-TETRAHYDROQUINOLINE(59611-52-8)1HNMR

59611-52-8(6-Fluoro-1,2,3,4-tetrahydroquinoline)Related Search:

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Quinoline, 6-fluoro-1,2,3,4-tetrahydro- 6-Fluoro-1,2,3,4-tetrahydroquinoline,97% 6-Fluoro-1,2,3,4-tetrahydroquinoline 59611-52-8