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Cyclosporin C

Cyclosporin C structure

CAS No.: 59787-61-0

Chemical Name:: Cyclosporin C

Synonyms: CL246;CS-2546;CS-2545;WF-3484;CYCLOSPORIN C;Thr2-cyclosporine;Cyclosporin C, >=95%;Cyclosporine IMpurity-C;Cyclosporin Impurity C;Cyclosporine Impurity 3

CBNumber:: CB2153074

Molecular Formula:: C62H111N11O13

Molecular Weight:: 1218.61

MDL Number:: MFCD06410945

MOL File:: 59787-61-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

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Cyclosporin C Properties

Melting point	144-1460C
alpha	D20 -255° (c = 0.5 in chloroform); D20 -182° (c = 0.5 in methanol)
Boiling point	1316.0±65.0 °C(Predicted)
Density	1.033±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMSO: ≥10mg/mL
pka	13.06±0.70(Predicted)
form	Colorless to off-white crystalline solid.
color	White to Off-White
InChIKey	JTOKYIBTLUQVQV-PCACHRFWSA-N
CAS DataBase Reference	59787-61-0
FDA UNII	6S744L5508

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Danger

Hazard statements

H362-H350-H302

Precautionary statements

P264-P270-P301+P312-P330-P501-P201-P260-P263-P264-P270-P308+P313

WGK Germany

NFPA 704

	0
2		0

Cyclosporin C price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	29152	Cyclosporin C ≥95%	59787-61-0	1mg	$38	2026-04-30	Buy
Cayman Chemical	29152	Cyclosporin C ≥95%	59787-61-0	5mg	$129	2026-04-30	Buy
Cayman Chemical	29152	Cyclosporin C ≥95%	59787-61-0	10mg	$202	2026-04-30	Buy
Cayman Chemical	29152	Cyclosporin C ≥95%	59787-61-0	25mg	$363	2026-04-30	Buy
Usbiological	C8900-10	Cyclosporin C ~95%(HPLC)	59787-61-0	1mg	$362	2026-06-03	Buy

Product number	Packaging	Price	Buy
29152	1mg	$38	Buy
29152	5mg	$129	Buy
29152	10mg	$202	Buy
29152	25mg	$363	Buy
C8900-10	1mg	$362	Buy

Cyclosporin C Chemical Properties, Uses, Production

Description

Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. It is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs = 0.1-5 μg/ml). Cyclosporin C (15 μg/ml) inhibits vaccinia virus replication in infected BSC40 cells by 98.82%. It inhibits lymphocyte proliferation induced by the mitogens concanavalin A (ConA; ), phytohemagglutinin L (PHA), and pokeweed mitogen (PWM), as well as proliferation induced by alloantigen in mixed lymphocyte culture when used at a concentration of 100 ng/ml. Cyclosporin C (100 ng/ml) inhibits the local graft versus host (GVH) reaction in mice receiving splenocyte grafts.

Chemical Properties

White Solid

Uses

A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Uses

Cyclosporin C is a minor analogue of the cyclosporin complex produced by a number of fungal species, including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin C possesses immunosuppressant activity but has been much less extensively investigated than the major analogue, cyclosporin A.

storage

+4°C

References

[1] A VON WARTBURG R T. Cyclosporins, fungal metabolites with immunosuppressive activities.[J]. Progress in medicinal chemistry, 1988, 25: 1-33. DOI: 10.1016/s0079-6468(08)70276-5
[2] M MOUSSAF. Cyclosporin C is the main antifungal compound produced by Acremonium luzulae.[J]. Applied and Environmental Microbiology, 1997, 63 5: 1739-1743. DOI: 10.1128/aem.63.5.1739-1743.1997
[3] C R DAMASO N M. Inhibition of vaccinia virus replication by cyclosporin A analogues correlates with their affinity for cellular cyclophilins.[J]. Journal of General Virology, 1998, 79 ( Pt 2): 339-346. DOI: 10.1099/0022-1317-79-2-339
[4] N SADEG. In vitro and in vivo comparative studies on immunosuppressive properties of cyclosporines A, C, D and metabolites M1, M17 and M21.[J]. Immunopharmacology and Immunotoxicology, 1993, 15 2-3: 163-177. DOI: 10.3109/08923979309025992

Cyclosporin C Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclosporin A

Cyclosporin C Suppliers

Global Suppliers ( 219)

Supplier	Tel	Email	Country	ProdList	Advantage
Hefei fuya biotechnology co. LTD	18096409024	sales02@foreversyn.com	China	1934	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2915	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	5996	61
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Fujian Kerui Pharmaceutical Co., Ltd.	+86-591-83309157; 18505919179	23115188@qq.com	China	18	62
Hunan Hui Bai Shi Biotechnology Co., Ltd.	0731-85526065 13308475853	ivy@hnhbsj.com	China	7236	62
Chengdu Biopurify Phytochemicals Ltd.	+86-028-82633397 18982077548	cwb1@biopurify.cn	China	2376	60
Chengdu Climax Biotech Co., Ltd.	028-83311324 1278112614	climaxbiotech@gmail.com	China	925	58
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	5000	50

Supplier	Advantage
Hefei fuya biotechnology co. LTD	58
Shanghai Boyle Chemical Co., Ltd.	55
J & K SCIENTIFIC LTD.	76
Chembest Research Laboratories Limited	61
Chemsky（shanghai）International Co.,Ltd.	50
Fujian Kerui Pharmaceutical Co., Ltd.	62
Hunan Hui Bai Shi Biotechnology Co., Ltd.	62
Chengdu Biopurify Phytochemicals Ltd.	60
Chengdu Climax Biotech Co., Ltd.	58
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50

View Latest Price from Cyclosporin C manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-15	Cyclosporin C 59787-61-0	$48.00-106.00		99.30%	10g	TargetMol Chemicals Inc.
2026-06-30	Cyclosporin C 59787-61-0		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-12-16	Cyclosporin C 59787-61-0		10mg	98	10000000	Moxin Chemicals

Cyclosporin C
59787-61-0
$48.00-106.00
99.30%
TargetMol Chemicals Inc.

Cyclosporin C
59787-61-0
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

Cyclosporin C
59787-61-0
98
Moxin Chemicals

Cyclosporin C Spectrum

Cyclosporin C(59787-61-0)¹HNMR

59787-61-0 (Cyclosporin C) Related Search:

Methyl acrylate Methylparaben STAUROSPORINE Phenylmethylsulfonyl fluoride Cyclosporin A

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Methyl Methyl bromide Parathion-methyl

1of4

CYCLOSPORIN C Cyclosporine C/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] 30-(1-hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriaconta CS-2545 CS-2546 cyclo-[MeBmt-Thr-Sar-MeLeu-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal] Cyclosporine EP Impurity C Thr2-cyclosporine Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Thr-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) WF-3484 7-L-Threoninecyclosporin A Cyclosporine IMpurity-C 7-L-Threoninecyclosporin A, WF 3484 7-Threonine-cyclosporin A Cyclosporin C, >=95% CL246 Cyclosporin Impurity C Cyclosporin Impurity 3(Cyclosporin C) Cyclosporin A, 7-L-threonine- Cyclosporine Impurity 3 (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1-Hydroxy-2-methylhex-4-en-1-yl)-30-((R)-1-hydroxyethyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone (3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,1 (3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone Cyclosporin C, EvoPure? (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-30-[(1R)-1-hydroxyethyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone (3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nomethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone 59787-61-0 69787-61-0 59767-61-0 C62H111N11O13 Intermediates & Fine Chemicals Peptides Pharmaceuticals ACTIVE PHARMACEUTICAL INGREDIENTS