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Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione structure

CAS No.: 21038-67-5

Chemical Name:: Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione

Synonyms: pyrido[3,4-d]pyriMidine-2,4-diol;1H-pyrido[3,4-d]pyrimidine-2,4-dione;2,4-Dihydroxypyrido[3,4-d]pyrimidine;Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione;Pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione 95%;1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione;1H,2H,3H,4H-pyrido[2,3-d]pyriMidine-2,4-dione;Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione - [P71315]

CBNumber:: CB2156196

Molecular Formula:: C7H5N3O2

Molecular Weight:: 163.13

MDL Number:: MFCD07438024

MOL File:: 21038-67-5.mol

MSDS File:: SDS

Last updated:2026-09-12 18:50:23

Request For Quotation

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione Properties

Melting point	>320 °C
Density	1.424±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	9.01±0.20(Predicted)
Appearance	Off-white to gray Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
HS Code	2933998090

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	NP44307	Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione	21038-67-5	100mg	$250	2026-06-04	Buy
Biosynth	NP44307	Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione	21038-67-5	50mg	$250	2026-06-04	Buy
Biosynth	NP44307	Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione	21038-67-5	250mg	$487.5	2026-06-04	Buy
Apolloscientific	OR322698	Pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione >97%	21038-67-5	100mg	$25	2026-06-04	Buy
Apolloscientific	OR322698	Pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione >97%	21038-67-5	250mg	$30	2026-06-04	Buy

Product number	Packaging	Price	Buy
NP44307	100mg	$250	Buy
NP44307	50mg	$250	Buy
NP44307	250mg	$487.5	Buy
OR322698	100mg	$25	Buy
OR322698	250mg	$30	Buy

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione Chemical Properties, Uses, Production

Synthesis

64188-97-2

32315-10-9

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

21038-67-5

To a solution of 3-aminopyridine-4-carboxamide (5 g, 36.5 mmol) in tetrahydrofuran (THF, 100 mL) was sequentially added triphosgene (11.9 g, 40.1 mmol) and triethylamine (TEA, 7.4 g, 73 mmol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, the solution was concentrated under reduced pressure and the residue was ground with an appropriate amount of water. The solid product was collected by filtration and washed sequentially with water and THF. The solid was dried to give pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione 4.1 g in 70% yield. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 11.62 (s, 1H), 11.58 (s, 1H), 8.66 (s, 1H), 8.40 (d, 1H, J = 5.2 Hz), 7.80 (d, 1H, J = 5.2 Hz).

References

[1] Patent: WO2014/151106, 2014, A1. Location in patent: Paragraph 00108
[2] Patent: WO2016/44429, 2016, A1. Location in patent: Paragraph 00154; 00155

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione Preparation Products And Raw materials

Raw materials

3-Aminoisonicotinic acid Carbon dioxide 3-Amino-4-pyridinecarboxamide Triphosgene 3-Amino-4-cyanopyridine

Urea Triethylamine Tetrahydrofuran

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Preparation Products

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione Suppliers

Global Suppliers ( 75)

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Shangchem Co., Ltd.	+86-21-68182121		China	881	52
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Nanjing Norris-Pharm Technology Co., Ltd	13901585132	sales@norris-pharm.com	China	8869	55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 13913916777	cfzhang@aikonchem.com	China	19902	55
Shanghai Witofly Chemical Co.,Ltd		sales@witofly.com	China	2853	52
Shanghai Raise Chemical Technology Co.,Ltd	+86-021-50935922		China	7854	55
Shanghai Huikai Chemical Technology Co., Ltd.	021-61995394 18916691159	chemicalsea@163.com	China	1970	58
Shanghai Worldyang Chemical Co.,Ltd.	021-56795766	sales@worldyachem.com	China	9475	58
Jiaxing Novartis Chemical Co., Ltd.	18957373295		China	1579	58

Supplier	Advantage
Capot Chemical Co., Ltd	66
Shangchem Co., Ltd.	52
Pure Chemistry Scientific Inc.	62
Nanjing Norris-Pharm Technology Co., Ltd	55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	55
Shanghai Witofly Chemical Co.,Ltd	52
Shanghai Raise Chemical Technology Co.,Ltd	55
Shanghai Huikai Chemical Technology Co., Ltd.	58
Shanghai Worldyang Chemical Co.,Ltd.	58
Jiaxing Novartis Chemical Co., Ltd.	58

View Latest Price from Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-06	PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 21038-67-5	$3.00	1KG	98%	100KG	Career Henan Chemical Co

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE
21038-67-5
$3.00
98%
Career Henan Chemical Co

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione Spectrum

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE(21038-67-5)¹HNMR

21038-67-5 (Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione) Related Search:

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3-Amino-4-pyridinecarboxamide 4-Aminomethyl-pyridin-3-ylamine pyrido[3,4-b]pyrazin-5-ylmethanamine pyrido[4,3-d]pyrimidin-4-amine Pyrido[4,3-d]pyriMidine-2,4(1H,3H)-dione

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1H,2H,3H,4H-pyrido[2,3-d]pyriMidine-2,4-dione 2,4-Dihydroxypyrido[3,4-d]pyrimidine 1H-pyrido[3,4-d]pyrimidine-2,4-dione 1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione Pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione 95% Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione - [P71315] pyrido[3,4-d]pyriMidine-2,4-diol Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione 21038-67-5 Heterocycle-Pyrimidine series