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PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE structure

CAS No.: 21038-67-5

Chemical Name:: PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

Synonyms: pyrido[3,4-d]pyriMidine-2,4-diol;1H-pyrido[3,4-d]pyrimidine-2,4-dione;2,4-Dihydroxypyrido[3,4-d]pyrimidine;PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE;Pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione 95%;1H,2H,3H,4H-pyrido[2,3-d]pyriMidine-2,4-dione;1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione;Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione - [P71315]

CBNumber:: CB2156196

Molecular Formula:: C7H5N3O2

Molecular Weight:: 163.13

MDL Number:: MFCD07438024

MOL File:: 21038-67-5.mol

Last updated:2025-07-24 18:13:46

Product description	Number	Pack Size	Price
Pyrido[3,4-D]pyrimidine-2,4(1H,3H)-dione	P997305	100mg	$110
pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 95%	BP-20262	1g	$100
pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione 96%	BP-20263	500mg	$145
1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione	4H53-1-49	250mg	$240
pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione 96%	BP-20263	1g	$250
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PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Properties

Melting point	>320 °C
Density	1.424±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	9.01±0.20(Predicted)
Appearance	Off-white to gray Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
HS Code	2933998090

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	P997305	Pyrido[3,4-D]pyrimidine-2,4(1H,3H)-dione	21038-67-5	100mg	$110	2021-12-16	Buy
BroadPharm	BP-20262	pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 95%	21038-67-5	1g	$100	2021-12-16	Buy
BroadPharm	BP-20263	pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione 96%	21038-67-5	500mg	$145	2021-12-16	Buy
SynQuest Laboratories	4H53-1-49	1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione	21038-67-5	250mg	$240	2021-12-16	Buy
BroadPharm	BP-20263	pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione 96%	21038-67-5	1g	$250	2021-12-16	Buy

Product number	Packaging	Price	Buy
P997305	100mg	$110	Buy
BP-20262	1g	$100	Buy
BP-20263	500mg	$145	Buy
4H53-1-49	250mg	$240	Buy
BP-20263	1g	$250	Buy

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Chemical Properties,Uses,Production

Synthesis

64188-97-2

32315-10-9

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

21038-67-5

To a solution of 3-aminopyridine-4-carboxamide (5 g, 36.5 mmol) in tetrahydrofuran (THF, 100 mL) was sequentially added triphosgene (11.9 g, 40.1 mmol) and triethylamine (TEA, 7.4 g, 73 mmol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, the solution was concentrated under reduced pressure and the residue was ground with an appropriate amount of water. The solid product was collected by filtration and washed sequentially with water and THF. The solid was dried to give pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione 4.1 g in 70% yield. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 11.62 (s, 1H), 11.58 (s, 1H), 8.66 (s, 1H), 8.40 (d, 1H, J = 5.2 Hz), 7.80 (d, 1H, J = 5.2 Hz).

References

[1] Patent: WO2014/151106, 2014, A1. Location in patent: Paragraph 00108
[2] Patent: WO2016/44429, 2016, A1. Location in patent: Paragraph 00154; 00155

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Preparation Products And Raw materials

Raw materials

3-Aminoisonicotinic acid Carbon dioxide 3-AMINO-4-PYRIDINECARBOXAMIDE Triphosgene 3-AMINO-4-CYANOPYRIDINE

Urea Triethylamine Tetrahydrofuran

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Preparation Products

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Suppliers

Global( 72)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Shanghai Scochem Technology Co., Ltd	+86-021-33758897 +86-13701882790	sales@scochem.com	China	1977	58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	+8618235132063	sales@tihondan.com	China	3767	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53899	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shenzhen Nexconn Pharmatechs Ltd	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Labnetwork lnc.	58
Shanghai Scochem Technology Co., Ltd	58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Amadis Chemical Company Limited	58

View Lastest Price from PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-06	PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 21038-67-5	US $3.00 / KG	1KG	98%	100KG	Career Henan Chemical Co

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE
21038-67-5
US $3.00 / KG
98%
Career Henan Chemical Co

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Spectrum

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE(21038-67-5)¹HNMR

21038-67-5(PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE)Related Search:

pyrido[2,3-b]pyrazin-2(1H)-one PYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE Pyrido[4,3-d]pyrimidin-5(6H)-one (9CI) PYRROLO[1,2-A]QUINOXALIN-4(5H)-ONE 4-AMINOMETHYL-PYRIDIN-3-YLAMINE

PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 3-AMINO-4-PYRIDINECARBOXAMIDE pyrido[3,4-b]pyrazin-5-ylmethanamine pyrido[4,3-d]pyrimidin-4-amine Pyrido[4,3-d]pyriMidine-2,4(1H,3H)-dione

Pyrido[4,3-d]pyrimidine-2,4-diamine PYRIDO[3,2-D]PYRIMIDIN-4-AMINE Pyrido[3,2-d]pyrimidine-2,4-diamine pyrido[3,4-b]pyrazine-5-carboxylic acid pyrido[3,4-b]pyrazine-5-carbonitrile

pyrido[3,4-d]pyrimidine-2,4-diamine Pyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione pyrido[3,2-d]pyrimidin-2-amine

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PYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 1H,2H,3H,4H-pyrido[2,3-d]pyriMidine-2,4-dione pyrido[3,4-d]pyriMidine-2,4-diol 2,4-Dihydroxypyrido[3,4-d]pyrimidine 1H-pyrido[3,4-d]pyrimidine-2,4-dione 1H,2H,3H,4H-Pyrido[3,4-d]pyrimidine-2,4-dione Pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione 95% Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione - [P71315] 21038-67-5 Heterocycle-Pyrimidine series