5-chloro-N-methylpyridin-2-amine
- CAS No.
- 4214-80-6
- Chemical Name:
- 5-chloro-N-methylpyridin-2-amine
- Synonyms
- UKRORGSYN-BB BBR-009506;5-Chloro-2-MethylaMinopyridine;5-Chloro-2-(MethylaMino)pyridine;5-chloro-N-methylpyridin-2-amine;5-Chloro-N-methyl-2-pyridinamine;5-Chloro-N-Methyl-2-pyridineaMine;2-PyridinaMine, 5-chloro-N-Methyl-;5-Chloro-N-methylpyridin-2-ylamine;(5-Chloro-pyridin-2-yl)-methyl-amine
- CBNumber:
- CB21778216
- Molecular Formula:
- C6H7ClN2
- Molecular Weight:
- 142.59
- MDL Number:
- MFCD00955783
- MOL File:
- 4214-80-6.mol
| Product description | Number | Pack Size | Price |
| 5-Chloro-2-methylaminopyridine | TRC-C369060-500MG | 500mg | $109 |
| 5-Chloro-2-methylaminopyridine | TRC-C369060-250MG | 250mg | $91 |
| 5-Chloro-2-methylaminopyridine | TRC-C369060-100MG | 100mg | $72 |
| 5-Chloro-N-methylpyridin-2-amine 97% | OR927031 | 250mg | $26 |
| 5-Chloro-N-methylpyridin-2-amine 97% | OR927031 | 1g | $33 |
| More product size | |||
| Melting point | 63-65°C |
|---|---|
| Boiling point | 247℃ |
| Density | 1.250 |
| Flash point | 103℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO, Methanol |
| form | Solid |
| pka | 5.00±0.10(Predicted) |
| color | Off-White |
| InChI | InChI=1S/C6H7ClN2/c1-8-6-3-2-5(7)4-9-6/h2-4H,1H3,(H,8,9) |
| InChIKey | KSISYWKRGRATSK-UHFFFAOYSA-N |
| SMILES | C1(NC)=NC=C(Cl)C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933399990 |
5-chloro-N-methylpyridin-2-amine price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-C369060-500MG | 5-Chloro-2-methylaminopyridine | 4214-80-6 | 500mg | $109 | 2026-06-03 | Buy |
| TRC | TRC-C369060-250MG | 5-Chloro-2-methylaminopyridine | 4214-80-6 | 250mg | $91 | 2026-06-03 | Buy |
| TRC | TRC-C369060-100MG | 5-Chloro-2-methylaminopyridine | 4214-80-6 | 100mg | $72 | 2026-06-03 | Buy |
| Apolloscientific | OR927031 | 5-Chloro-N-methylpyridin-2-amine 97% | 4214-80-6 | 250mg | $26 | 2026-06-04 | Buy |
| Apolloscientific | OR927031 | 5-Chloro-N-methylpyridin-2-amine 97% | 4214-80-6 | 1g | $33 | 2026-06-04 | Buy |
5-chloro-N-methylpyridin-2-amine Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
5-Chloro-2-methylaminopyridine is used in the preparation of aminosulfuranes with N-heterocyclic groups.
Synthesis
1072-98-6
7318-81-2
4214-80-6
GENERAL METHOD: Copper(II) acetate (0.550 g, 3.03 mmol) was added to a solution of 2-amino-5-chloropyridine (1.22 mmol) and pyridine (0.34 mL, 4.24 mmol) in dioxane (15 mL). The mixture was stirred for 15 min, methylboronic acid (0.181 g, 3.03 mmol) was added and the reaction was refluxed until the 2-amino-5-chloropyridine was completely consumed (reaction time monitored by TLC analysis, 1.5-18 h). The reaction mixture was allowed to cool to room temperature, filtered through diatomaceous earth and the solvent was evaporated. The residue was purified by fast chromatography (elution gradient: 0→50% ethyl acetate/hexane) to give 5-chloro-N-methylpyridin-2-amine (162). Preparation of 5-chloro-N-methylpyridin-2-amine (162): compound 162 was prepared from 2-amino-5-chloropyridine (160) according to the above method F. 73 mg of brown powder was obtained in 42% yield. 1H NMR (500 MHz, CDCl3) δ 2.90 (s, 3H), 4.79 (br s, 1H), 6.33 (d, J = 8.9 Hz, 1H), 7.38 (dd, J = 2.6, 8.9 Hz, 1H), 8.02 (d, J = 2.6 Hz, 1H). 13C NMR (126 MHz, CDCl3) δ 29.22, 106.90, 119.44, 137.27, 146.26, 157.88. LC-MS (M + H+) calculated value C6H7ClN2 143, measured value 143.
References
[1] Patent: WO2014/100833, 2014, A1. Location in patent: Paragraph 0081; 0233
5-chloro-N-methylpyridin-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 17389186172 | 1077@dideu.com | China | 3999 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hong-chuang Pharma Tech Co., Ltd. | 18151128828 | hc-sales@foxmail.com | China | 2636 | 55 |
View Lastest Price from 5-chloro-N-methylpyridin-2-amine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | 5-Chloro-N-methyl-2-pyridineamine
4214-80-6
|
$20.00-100.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-02-18 | 5-chloro-N-methylpyridin-2-amine
4214-80-6
|
$7.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 5-Chloro-N-methyl-2-pyridineamine
4214-80-6
- $20.00-100.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-chloro-N-methylpyridin-2-amine
4214-80-6
- $7.00
- 99%
- Career Henan Chemical Co
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