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4-(4-Nitrophenyl)morpholine

CAS No.
10389-51-2
Chemical Name:
4-(4-Nitrophenyl)morpholine
Synonyms
AURORA 1260;BUTTPARK 97\12-12;TIMTEC-BB SBB006371;p-Morpholinonitrobenzene;4-Morpholinyl nitrobenzene;4-MORPHOLINO NITRO BENZENE;4-Morpholino-1-nitrobenzene;4-(P-NITROPHENYL)MORPHOLINE;4-(p-nitrophenyl)-morpholin;4-(4-nitrophenyl)-morpholin
CBNumber:
CB2178277
Molecular Formula:
C10H12N2O3
Molecular Weight:
208.21
MDL Number:
MFCD00023317
MOL File:
10389-51-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:50:25

4-(4-Nitrophenyl)morpholine Properties

Melting point 152 °C
Boiling point 386.2±37.0 °C(Predicted)
Density 1.265±0.06 g/cm3(Predicted)
RTECS QE7405000
storage temp. Storage temp. 2-8°C
solubility soluble in Dimethylformamide
pka 0.81±0.40(Predicted)
form powder to crystal
color Light yellow to Yellow to Orange
λmax 375nm(Dioxane)(lit.)
InChI InChI=1S/C10H12N2O3/c13-12(14)10-3-1-9(2-4-10)11-5-7-15-8-6-11/h1-4H,5-8H2
InChIKey IAJDSUYFELYZCS-UHFFFAOYSA-N
SMILES N1(C2=CC=C([N+]([O-])=O)C=C2)CCOCC1
CAS DataBase Reference 10389-51-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII QQ5L4U8QQS
EPA Substance Registry System Morpholine, 4-(4-nitrophenyl)- (10389-51-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  40-42/43-63
Safety Statements  26-36
RIDADR  1662
TSCA  TSCA listed
HS Code  2934999090
NFPA 704
1
2 0

4-(4-Nitrophenyl)morpholine price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S447625 4-(4-NITROPHENYL)MORPHOLINE AldrichCPR 10389-51-2 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S447625 4-(4-NITROPHENYL)MORPHOLINE Aldrich 10389-51-2 1g $179 2024-03-01 Buy
TCI Chemical N1124 4-(4-Nitrophenyl)morpholine >98.0%(GC)(T) 10389-51-2 5g $18 2026-04-30 Buy
TCI Chemical N1124 4-(4-Nitrophenyl)morpholine >98.0%(GC)(T) 10389-51-2 25g $50 2026-04-30 Buy
AstaTech 64907 4-(4-NITROPHENYL)MORPHOLINE 97% 10389-51-2 100G $71 2026-04-30 Buy
Product number Packaging Price Buy
S447625 1 unit $197 Buy
S447625 1g $179 Buy
N1124 5g $18 Buy
N1124 25g $50 Buy
64907 100G $71 Buy

4-(4-Nitrophenyl)morpholine Chemical Properties,Uses,Production

Synthesis Reference(s)

Synthesis, p. 1145, 1990 DOI: 10.1055/s-1990-27118

Synthesis

Morpholine

110-91-8

1-Iodo-4-nitrobenzene

636-98-6

4-(4-NITROPHENYL)MORPHOLINE

10389-51-2

GENERAL METHODS: Aryl halides (1.0 mmol), morpholine (1 mmol), sodium tert-butoxide (2 mmol) and 0.2 mol% of Pd/Nf-G catalyst were sequentially added to 1 mL of dimethyl sulfoxide (DMSO). The reaction mixture was stirred at 110 °C for 12 h. The reaction process was monitored by gas chromatography (GC). Upon completion of the reaction, the mixture was cooled to room temperature and extracted with ethyl acetate. The catalyst was recovered by simple filtration and subsequently washed with ethanol, dried and stored for subsequent use. The crude product was purified by column chromatography with the eluent being a mixed petroleum ether/ethyl acetate solvent. The recovered catalyst was reused in subsequent recyclability studies. The conversion of the reactants was determined by gas chromatography (GC).

References

[1] Bulletin of the Chemical Society of Japan, 1991, vol. 64, # 1, p. 42 - 49
[2] Applied Organometallic Chemistry, 2013, vol. 27, # 12, p. 704 - 706
[3] RSC Advances, 2014, vol. 4, # 96, p. 53387 - 53396
[4] Tetrahedron Letters, 2015, vol. 56, # 30, p. 4463 - 4467
[5] Tetrahedron Letters, 2016, vol. 57, # 14, p. 1532 - 1536

4-(4-Nitrophenyl)morpholine Preparation Products And Raw materials

Global( 202)Suppliers
Supplier Tel Email Country ProdList Advantage
Taizhou Synhigher Biomedical Co., Ltd. 0523-86819336; 13357797105 contact@synhigher.com China 75 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shangchem Co., Ltd. +86-21-68182121 China 881 52
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
China Langchem Inc. 0086-21-58956006 China 7798 57
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
Shanghai civi chemical technology co.,Ltd 86-21-34053660 sale@labgogo.com China 9853 52

View Lastest Price from 4-(4-Nitrophenyl)morpholine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(4-NITROPHENYL)MORPHOLINE pictures 2019-07-06 4-(4-NITROPHENYL)MORPHOLINE
10389-51-2
$7.00 1KG 99% 100KG Career Henan Chemical Co
TIMTEC-BB SBB006371 N-(4-NITROPHENYL)MORPHOLINE 4-(4-nitrophenyl)-morpholin 4-(p-nitrophenyl)-morpholin 4-(P-NITROPHENYL)MORPHOLINE 4-MORPHOLINO NITRO BENZENE AURORA 1260 BUTTPARK 97\12-12 4-Morpholino-1-nitrobenzene p-Morpholinonitrobenzene 4-Morpholinyl nitrobenzene Morpholine, 4-(4-nitrophenyl)- Morpholine, 4-(p-nitrophenyl)- N-(p-Nitrophenyl)morpholine N-(p-Nitrophenyl)-morpholine 4-(4-Nitrophenyl)morpholine-d8 1-morpholino-4-nitrobenzene 4-(4-Nitrophenyl)morpholine 10389-51-2 10839-51-2 98953 NITROBENZENE pharmacetical Benzene Derivative momelotinib