ChemicalBook >> CAS DataBase List >>Benzilic acid
Benzilic acid
- CAS No.
- 76-93-7
- Chemical Name:
- Benzilic acid
- Synonyms
- Benzylic acid;2-Hydroxy-2,2-diphenylacetic acid;benzilic;2,2-Diphenyl-2-hydroxyacetic acid;BENZILIC ACID;BENZILLIC ACID;TIMTEC-BB SBB003299;BENZILIC ACID, 99+%;DIPHENYLGLYCOLIC ACID;Diphenylglycollicacid
- CBNumber:
- CB2179830
- Molecular Formula:
- C14H12O3
- Molecular Weight:
- 228.25
- MDL Number:
- MFCD00004447
- MOL File:
- 76-93-7.mol
- MSDS File:
- SDS
Last updated:2026-05-27 23:59:25
| Melting point | 149-151 °C(lit.) |
|---|---|
| Boiling point | 180 °C |
| Density | 1.28 |
| refractive index | 1.5805 (estimate) |
| Flash point | 180°C/22mm |
| storage temp. | Store below +30°C. |
| solubility | 1.41g/l (experimental) |
| form | Powder |
| pka | pKa (25°): 3.036 |
| color | White to cream-white |
| Water Solubility | 1.41 g/L (25 ºC) |
| Merck | 14,1080 |
| BRN | 521402 |
| Stability | Stable. Incompatible with strong oxidizing agents. Combustible. |
| Cosmetics Ingredients Functions | BUFFERING |
| InChI | 1S/C14H12O3/c15-13(16)14(17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,17H,(H,15,16) |
| InChIKey | UKXSKSHDVLQNKG-UHFFFAOYSA-N |
| SMILES | OC(c2ccccc2)(c1ccccc1)C(=O)O |
| LogP | 2.300 |
| CAS DataBase Reference | 76-93-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 8F6J993XXR |
| NIST Chemistry Reference | Benzeneacetic acid, «alpha»-hydroxy-«alpha»-phenyl-(76-93-7) |
| EPA Substance Registry System | Benzilic acid (76-93-7) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P280f-P403+P233-P405 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-20/21/22 | |||||||||
| Safety Statements | 36-36/37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DD2064000 | |||||||||
| Autoignition Temperature | 530°C | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29181980 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazardous Substances Data | 76-93-7(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orl-mus: 2 g/kg AIPTAK 116,154,58 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Benzilic acid price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000432 | Trospium impurity A European Pharmacopoeia (EP) Reference Standard | 76-93-7 | 20 mg | $175 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR3154 | Trospium Chloride Related Compound A pharmaceutical secondary standard, certified reference material | 76-93-7 | 50MG | $593 | 2026-04-30 | Buy |
| Sigma-Aldrich | B5194 | Benzilic acid ≥99% | 76-93-7 | 100g | $36.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.00140 | Benzilic acid for synthesis | 76-93-7 | 250g | $92.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.00140 | Benzilic acid for synthesis | 76-93-7 | 1kg | $238 | 2026-04-30 | Buy |
Benzilic acid Chemical Properties, Uses, Production
Chemical Properties
white powder
Uses
Benzilic Acid is an impurity of Trospium (T892800), a tropine derivative with anticholinergic activity and a antiispasmodic agent.
Definition
ChEBI: Benzilic acid is a 2-hydroxy monocarboxylic acid.
Synthesis Reference(s)
The Journal of Organic Chemistry, 29, p. 1631, 1964 DOI: 10.1021/jo01029a509
Safety Profile
Moderately toxic by subcutaneousroute. Slightly toxic by ingestion. When heated todecomposition it emits acrid smoke and irritating vapors.
Purification Methods
Crystallise benzilic acid from *benzene (ca 6mL/g), or hot H2O. [Beilstein 10 IV 1256.]
Benzilic acid Preparation Products And Raw materials
BENZILIC ACID extrapure
Benzilic acidDiphenylglycolic acid
TrospiuM Chloride Related CoMpound A
Trospium Chloride Related Compound A (20 mg) (Benzilic Acid) (Internationally Restricted Sales Item)
BENZILIC ACID FOR SYNTHESIS 1 KG
BENZILIC ACID FOR SYNTHESIS 250 G
Benzeneacetic acid,a-hydroxy-a-phenyl-
Trospium Chloride Related Compound A (20 mg) (Benzilic Acid) (International Restricted Sales Item)
HYDROXY-DIPHENYL-ACETIC ACID
DIPHENYLGLYCOLIC ACID
BENZILIC ACID
2,2-DIPHENYL-2-HYDROXY ACETATE
.alpha.-hydroxy-.alpha.-phenyl-Benzeneaceticacid
TIMTEC-BB SBB003299
2-Hydroxy-2,2-diphenylaceticacid
Benzeneacetic acid, .alpha.-hydroxy-.alpha.-phenyl-
BENZILIC ACID, 99+%
BenzilicAcidForSynthesis
BENZILIC ACID (controlled chemical)
BENZILLIC ACID
Benzeneacetic acid, α-hydroxy-α-phenyl-
a,a-Diphenyl-a-hydroxyacetic acid
a,a-Diphenylglycolic acid
Acide diphenylhydroxyacetique
acidediphenylhydroxyacetique
a-Hydroxy-2,2-diphenylacetic acid
a-Hydroxy-a-phenylbenzeneacetic acid
a-Hydroxydiphenylacetic acid
alpha,alpha-Diphenyl-alpha-hydroxyacetic acid
alpha,alpha-Diphenylglycolic acid
alpha,alpha-diphenylglycolicacid
alpha-Hydroxy-2,2-diphenylacetic acid
alpha-Hydroxy-alpha-phenylbenzeneacetic acid
alpha-hydroxy-alpha-phenyl-benzeneaceticaci
alpha-hydroxy-alpha-phenylbenzeneaceticacid
Diphenylglycollicacid
Diphenylhydroxyacetic acid
diphenylhydroxyaceticacid
Glycolic acid, diphenyl-
-Hydroxy-phenylbenzeneaceticacid
Mandelic acid, alpha-phenyl-
Pipenzolate Impurity 1(Benzilic Acid)
Trospium Impurity 1（Trospium EP Impurity A）
2,2-dicyclohexyl-2-hydroxyacetate
Trospium EP Impurity A
Trospium impurity A CRS
Trospium EP Impurity A/ Trospium Related Compound A (Hydroxydiphenylacetic acid)
Trospium Chloride Related Compound A (F0J322)
Trospium Chloride Related Compound A (Benzilic Acid) (International Restricted Sales Item) (1699311)
Trospium Chloride Impurity A
Trospium Related Compound A
Trospium USP Related Compound A
hydroxydiphenylacetic acid (benzilic acid)
Diphenylethanolic acid
Trospium EP Impurity A (Trospium Chloride USP Related Compound A)
2,2-Diphenyl-2-hydroxyacetic acid
2-Hydroxy-2,2-diphenylacetic acid
benzilic
