Chlorodiphenylphosphine
- CAS No.
- 1079-66-9
- Chemical Name:
- Chlorodiphenylphosphine
- Synonyms
- DPPC;PH2PCL;PPh2Cl;ClPPh2;DIPHENYLCHLOROPHOSPHINE;DIPHENYLPHOSPHINOUS CHLORIDE;Diphenylphosphorus chloride;AURORA KA-1322;95% (C6H5)2PCl;Chlordiphenylphosphin
- CBNumber:
- CB6365608
- Molecular Formula:
- C12H10ClP
- Molecular Weight:
- 220.63
- MDL Number:
- MFCD00000529
- MOL File:
- 1079-66-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Chlorodiphenylphosphine 96% | C39601 | 25g | $69.6 |
| P-Chlorodiphenylphosphine 99% | 766054 | 25g | $112 |
| Chlorodiphenylphosphine >97.0%(T) | C0597 | 25g | $23 |
| Chlorodiphenylphosphine >97.0%(T) | C0597 | 100g | $64 |
| Diphenylchlorophosphine, min. 95% min.95% | 15-1551 | 50g | $58 |
| More product size | |||
| Melting point | 14-16°C |
|---|---|
| Boiling point | 320 °C(lit.) |
| Density | 1.229 g/mL at 25 °C(lit.) |
| vapor density | 7.8 (vs air) |
| vapor pressure | 1.3 hPa (20 °C) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | Miscible with alcohol. Slightly miscible with ammonia. |
| form | Liquid |
| color | Colorless to yellow |
| Specific Gravity | 1.229 |
| Water Solubility | Reacts violently |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| Sensitive | Air & Moisture Sensitive |
| BRN | 512032 |
| InChI | 1S/C12H10ClP/c13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H |
| InChIKey | XGRJZXREYAXTGV-UHFFFAOYSA-N |
| SMILES | ClP(c1ccccc1)c2ccccc2 |
| LogP | 5.330 (est) |
| CAS DataBase Reference | 1079-66-9(CAS DataBase Reference) |
| FDA UNII | WO975PJK1Y |
| NIST Chemistry Reference | Chlorodiphenylphosphine(1079-66-9) |
| EPA Substance Registry System | Phosphinous chloride, diphenyl- (1079-66-9) |
| UNSPSC Code | 12352128 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H290-H302-H314-H412 | |||||||||
| Precautionary statements | P273-P280-P301+P312+P330-P303+P361+P353-P305+P351+P338+P310 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 14-34-29-36 | |||||||||
| Safety Statements | 26-36/37/39-45-8-30-25-27 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| F | 1-9-19 | |||||||||
| Autoignition Temperature | 320 °C | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29310095 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 3 Eye Dam. 1 Met. Corr. 1 Skin Corr. 1B |
|||||||||
| Toxicity | LD50 orally in Rabbit: 316 mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
Chlorodiphenylphosphine price More Price(89)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C39601 | Chlorodiphenylphosphine 96% | 1079-66-9 | 25g | $69.6 | 2026-04-30 | Buy |
| Sigma-Aldrich | 766054 | P-Chlorodiphenylphosphine 99% | 1079-66-9 | 25g | $112 | 2026-04-30 | Buy |
| TCI Chemical | C0597 | Chlorodiphenylphosphine >97.0%(T) | 1079-66-9 | 25g | $23 | 2026-04-30 | Buy |
| TCI Chemical | C0597 | Chlorodiphenylphosphine >97.0%(T) | 1079-66-9 | 100g | $64 | 2026-04-30 | Buy |
| Strem Chemicals | 15-1551 | Diphenylchlorophosphine, min. 95% min.95% | 1079-66-9 | 50g | $58 | 2026-04-30 | Buy |
Chlorodiphenylphosphine Chemical Properties,Uses,Production
Chemical Properties
Colorless to light yellow liqui
Uses
Chlorodiphenylphosphine is used to introduce the diphenylphosphinyl moiety by aryl ortho-lithiation. It is also used as an intermediate to make antioxidants, flame retardants, stabilizers, catalysts, photoinitiators, and optical brighteners. Used as a halogenation reagent for the conversion of alcohols into halides, in the preparation of solid-phase reagent for the conversion of alcohols to alkyl halides.
Production Methods
The specific synthesis steps of Chlorodiphenylphosphine are as follows: In a sealed NMR tube filled with argon,Dissolve Ph2P (O) H (0.05 mmol) in 0.5 mL of tetrahydrofuran,Add acetyl chloride (the amount of acetyl chloride added is 1.2 times the equivalent of Ph2P (O) H),The mixture was reacted at 100 ° C for 12 hours with a yield of 99%.
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 3526, 1955 DOI: 10.1021/ja01618a030
Flammability and Explosibility
Non flammable
reaction suitability
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
Purification Methods
This air-sensitive, pale yellow lachrymatory liquid is purified by careful fractional distillation and discarding the lower boiling fraction which contains the main impurity PhPCl2 (b 48-51o/0.7mm), and checking for impurities by NMR. [Weinberg J Org Chem 40 3586 1975, Honer et al. Chem Ber 94 2122 1961, Beilstein 16 IV 969.]
Chlorodiphenylphosphine Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Z&T Chemical Co., Ltd | +86-021-33561011 +8613818804961 | Sales@ztchemical.com.cn | China | 546 | 58 |
| Jiangsu Nengyue New Material Technology Co.,Ltd | +undefined+86-13376001577 | robinlu.jian@foxmail.com | China | 64 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5225 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Guangzhou Xijia New Materials Co.,Ltd | +undefined13650882421 | ebswax@163.com | China | 99 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14014 | 58 |
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View Lastest Price from Chlorodiphenylphosphine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-15 | Chlorodiphenylphosphine
1079-66-9
|
1KG | 98% | 1000mt/year | Jinan Finer Chemical Co., Ltd | ||
 |
2026-05-28 | Chlorodiphenylphosphine
1079-66-9
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-04-28 | Chlorodiphenylphosphine
1079-66-9
|
1kg | 99% | 10000kg | Guangzhou Xijia New Materials Co.,Ltd |
-
- Chlorodiphenylphosphine
1079-66-9
- $0.00
- 98%
- Jinan Finer Chemical Co., Ltd
-
- Chlorodiphenylphosphine
1079-66-9
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Chlorodiphenylphosphine
1079-66-9
- $0.00
- 99%
- Guangzhou Xijia New Materials Co.,Ltd
