1H-Indazole-5-carbonitrile, 3-methyl-
- CAS No.
- 267875-55-8
- Chemical Name:
- 1H-Indazole-5-carbonitrile, 3-methyl-
- Synonyms
- 3-Methyl-1H-indazole-5-carbonitrile;3-methyl-2H-indazole-5-carbonitrile;1H-Indazole-5-carbonitrile, 3-methyl-
- CBNumber:
- CB21874813
- Molecular Formula:
- C9H7N3
- Molecular Weight:
- 157.17
- MDL Number:
- MFCD11846331
- MOL File:
- 267875-55-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
1H-Indazole-5-carbonitrile, 3-methyl- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA007MOB | 3-Methyl-1H-Indazole-5-Carbonitrile 97% | 267875-55-8 | 100mg | $96 | 2026-05-28 | Buy |
| aablocks | AA007MOB | 3-Methyl-1H-Indazole-5-Carbonitrile 97% | 267875-55-8 | 250mg | $157 | 2026-05-28 | Buy |
| aablocks | AA007MOB | 3-Methyl-1H-Indazole-5-Carbonitrile 97% | 267875-55-8 | 1g | $413 | 2026-05-28 | Buy |
| aablocks | AA007MOB | 3-Methyl-1H-Indazole-5-Carbonitrile 97% | 267875-55-8 | 5g | $1542 | 2026-05-28 | Buy |
| ACHEMBLOCK | S76362 | 3-methyl-1H-indazole-5-carbonitrile 97% | 267875-55-8 | 1G | $580 | 2026-05-27 | Buy |
1H-Indazole-5-carbonitrile, 3-methyl- Chemical Properties, Uses, Production
Synthesis
170230-87-2
267875-55-8
F. Synthesis of 3-methyl-1H-indazole-5-carbonitrile. An aqueous solution (2 mL) of sodium nitrite (3.6 g, 53 mmol) was slowly added dropwise to a solution of glacial acetic acid (150 mL) of 4-amino-3-ethylbenzonitrile (7.0 g, 48 mmol). The reaction mixture was stirred at room temperature for 16 hours and then concentrated under reduced pressure to one-third of the original volume, followed by the addition of water (200 mL). The pH of the aqueous phase was adjusted with saturated sodium bicarbonate solution to 10. The aqueous phase was extracted with ethyl acetate (3 × 200 mL), the organic extracts were combined and dried with anhydrous magnesium sulfate. After concentration of the organic phase under reduced pressure, the crude product was purified by rapid chromatography on silica gel (eluent: 0-45% hexane solution of ethyl acetate) to afford 3-methyl-1H-indazole-5-carbonitrile as an orange solid (3.3 g, 21 mmol, 30% yield). Mass spectrum (ESI) m/z 158.2 [M + H]+.
References
[1] Patent: US2008/242694, 2008, A1. Location in patent: Page/Page column 67-68
1H-Indazole-5-carbonitrile, 3-methyl- Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2277 | 58 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Beyond Pharmaceutical Co., Ltd | 0571-81953185 +86-15381198709 | jasonyao@bydpharma.com | China | 852 | 60 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22344 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| 3A Chemicals | 400-668-9898 | service@3achem.com | China | 20535 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
| Zhejiang Lianshuo Biotechnology Co., Ltd. | 18616526224 | lianshuo@vip.126.com | China | 9605 | 58 |
