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alpha-Hydroxy-gamma-butyrolactone

alpha-Hydroxy-gamma-butyrolactone structure

CAS No.: 19444-84-9

Chemical Name:: alpha-Hydroxy-gamma-butyrolactone

Synonyms: 2-HYDROXY-GAMMA-BUTYROLACTONE;3-Hydroxydihydrofuran-2(3H)-one;3-hydroxyoxolan-2-one;2-Hydroxytetrahydrofuran-2-one;AKOS 224;Empagliflozin-C-1;3-Hydroxyoxolane-2-one;2-Hydroxybutyrolactone.;Alpha-hydroxybutylactone;a-Hydroxy-g-butyrolactone

CBNumber:: CB2193218

Molecular Formula:: C4H6O3

Molecular Weight:: 102.09

MDL Number:: MFCD00134268

MOL File:: 19444-84-9.mol

MSDS File:: SDS

Last updated:2026-09-12 18:50:25

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alpha-Hydroxy-gamma-butyrolactone Properties

Boiling point	133 °C/10 mmHg (lit.)
Density	1.309 g/mL at 25 °C (lit.)
refractive index	n20/D 1.468(lit.)
Flash point	>230 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Sparingly), Methanol (Slightly)
pka	13.07±0.20(Predicted)
form	Viscous Liquid
color	Clear colorless to yellow
BRN	80587
InChI	InChI=1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2
InChIKey	FWIBCWKHNZBDLS-UHFFFAOYSA-N
SMILES	O1CCC(O)C1=O
LogP	-1.830 (est)
CAS DataBase Reference	19444-84-9(CAS DataBase Reference)
FDA UNII	L5D4QZ05QR
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

PPE

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Hazard Codes

Risk Statements

36/37/38

Safety Statements

23-24/25-36-26

WGK Germany

3-10

HS Code

29322090

Storage Class

10 - Combustible liquids

REACH Registrations

Active

NFPA 704

	1
0		0

alpha-Hydroxy-gamma-butyrolactone price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	364037	α-Hydroxy-γ-butyrolactone technical grade	19444-84-9	5g	$218	2026-04-30	Buy
TCI Chemical	H1802	3-Hydroxydihydrofuran-2(3H)-one (99.999%, trace metals basis) min. 98.0 %	19444-84-9	5G	$202	2026-04-30	Buy
TCI Chemical	H0788	alpha-Hydroxy-gamma-butyrolactone >98.0%(GC)	19444-84-9	10g	$331	2026-04-30	Buy
TCI Chemical	H0788	alpha-Hydroxy-gamma-butyrolactone >98.0%(GC)	19444-84-9	25g	$661	2026-04-30	Buy
TRC	TRC-B443818-500MG	Alpha-Hydroxy-Gamma-butyrolactone	19444-84-9	500mg	$103	2026-06-03	Buy

Product number	Packaging	Price	Buy
364037	5g	$218	Buy
H1802	5G	$202	Buy
H0788	10g	$331	Buy
H0788	25g	$661	Buy
TRC-B443818-500MG	500mg	$103	Buy

alpha-Hydroxy-gamma-butyrolactone Chemical Properties, Uses, Production

Chemical Properties

clear colorless to yellow viscous liquid

Uses

α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.

General Description

α-Hydroxy-γ-butyrolactone is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde.

Purification Methods

It has been purified by repeated fractionation and forms a colourless liquid. It has to be distilled at high vacuum; otherwise it will dehydrate. The acetox

alpha-Hydroxy-gamma-butyrolactone Preparation Products And Raw materials

Raw materials

Preparation Products

2,4-dihydroxy-Butanoic acid 2-Oxotetrahydrofuran-3-yl methacrylate

alpha-Hydroxy-gamma-butyrolactone Suppliers

Global Suppliers ( 165)

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Nuobeike Biological Technology Co., Ltd.	13962527677	1551481742@qq.com	China	298	58
Shanghai Xingui Biotechnology Co., Ltd.	15121041756	xingui2022@126.com	China	9954	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64

Supplier	Advantage
Suzhou Nuobeike Biological Technology Co., Ltd.	58
Shanghai Xingui Biotechnology Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Beijing Ouhe Technology Co., Ltd	60
Adamas Reagent, Ltd.	59
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64

View Latest Price from alpha-Hydroxy-gamma-butyrolactone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-15	ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 19444-84-9	$1.50	1g	99.0% Min	10 Tons	Shaanxi Didu New Materials Co. Ltd
2026-03-20	ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 19444-84-9	$10.00	1KG	99%	5tons	Hebei Chuanghai Biotechnology Co., Ltd
2024-04-25	3-Hydroxydihydro-2(3H)-furanone 19444-84-9	$5.00	1kg	99.92%	50000tons	Ouhuang Engineering Materials (Hubei) Co., Ltd

ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
19444-84-9
$1.50
99.0% Min
Shaanxi Didu New Materials Co. Ltd

ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
19444-84-9
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

3-Hydroxydihydro-2(3H)-furanone
19444-84-9
$5.00
99.92%
Ouhuang Engineering Materials (Hubei) Co., Ltd

alpha-Hydroxy-gamma-butyrolactone Spectrum

ALPHA-HYDROXY-GAMMA-BUTYROLACTONE(19444-84-9)MS ALPHA-HYDROXY-GAMMA-BUTYROLACTONE(19444-84-9)¹HNMR ALPHA-HYDROXY-GAMMA-BUTYROLACTONE(19444-84-9)¹³CNMR ALPHA-HYDROXY-GAMMA-BUTYROLACTONE(19444-84-9)IR1 ALPHA-HYDROXY-GAMMA-BUTYROLACTONE(19444-84-9)Raman

19444-84-9 (alpha-Hydroxy-gamma-butyrolactone) Related Search:

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1of4

DIHYDRO-3-HYDROXY-2(3H)-FURANONE 3-HYDROXYTETRAHYDROFURAN-2-ONE AKOS 224 4,5-Dihydro-3-hydroxy-2(3H)-furanone α-Hydroxy-γ-butyrolactone 4,5-Dihydroxy-3-hydroxy-2(3H)-furanone ALPHA-HYDROXY-GAMMA-BUTYROLACTONE, TECH. a-Hydroxy-g-butyrolactone 2-Hydroxybutyrolactone. α-Hydroxy-gama-butyrolactone, GC 99% 2-HYDROXY-GAMMA-BUTYROLACTONE 99% 2-Hydroxy-G-Butyrolactone 3-Hydroxy-4,5-dihydro-2(3H)-furanone 3-Hydroxy-4,5-dihydrofuran-2(3H)-one 3-Hydroxyoxolane-2-one 2-Hydroxy-gamma-butyrolactone,99% α-Hydroxy-gamma-butyrolactone 3-Hydroxy-dihydro-furan-2-one Dihydro-3-hydroxy-2(3H)-furanone 3-Hydroxytetrahydrofuran-2-one (3RS)-Dihydro-3-hydroxy-2(3H)-furanone a-Hydroxy-gaMa-butyrolactone alpha-Hydroxy-gaMMa-butyrolactone technical grade 3-Hydroxydihydrofuran-2(3H) Alpha-hydroxybutylactone α-Hydroxy-γ-butyrolactone> 2(3H)-Furanone, dihydro-3-hydroxy- 2(3H)-Furanone, dihydrohydroxy- Empagliflozin Impurity 144 3-hydroxydihydro-2(3H)-furanone α-Hydroxy-γ-butyrolactone α-Hydroxy-γ-butyrolactone, CAS 19444-84-9 Empagliflozin-C-1 2-HYDROXY-GAMMA-BUTYROLACTONE 2-Hydroxytetrahydrofuran-2-one 3-Hydroxydihydrofuran-2(3H)-one 3-hydroxyoxolan-2-one a-Hydroxy-γ-butyrolactone alpha-Hydroxy-gamma-butyrolactone 19444-84-9 194444-84-9 KETONE Organic Building Blocks Lactones Carbonyl Compounds Building Blocks