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(+)-DIACETYL-L-TARTARIC ANHYDRIDE

(+)-DIACETYL-L-TARTARIC ANHYDRIDE structure

CAS No.: 6283-74-5

Chemical Name:: (+)-DIACETYL-L-TARTARIC ANHYDRIDE

Synonyms: DATA;NSC 7712;DIACETYL-L-TARTARIC ANHYDRIDE;DI-O-ACETYL-L-TARTARIC ANHYDRIDE;(+)-Diacetyl-L-tartaric Anhydride;(+)-DI-O-ACETYL-L-WEINSURE-ANHYDRID;(+)-Diacetyl-L-tartaricAnhydride>(+)-DI-O-ACETYL-L-TARTARIC ANHYDRIDE;O,O-diacetyl tartaric acid anhydride;(R,R)-DIACETYLTARTARIC ACID ANHYDRIDE

CBNumber:: CB0717661

Molecular Formula:: C8H8O7

Molecular Weight:: 216.14

MDL Number:: MFCD00037918

MOL File:: 6283-74-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 22:51:34

Product description	Number	Pack Size	Price
(+)-O,O′-Diacetyl-L-tartaric anhydride 97%	358924	50g	$217
(+)-Diacetyl-L-tartaric Anhydride >97.0%(T)	D1911	25g	$52
Di-O-acetyl-L-tartaric Anhydride	D3441-60A	500mg	$319
Di-O-acetyl-L-tartaric Anhydride	TRC-D400570-500MG	500mg	$72
Di-O-acetyl-L-tartaric Anhydride	TRC-D400570-2G	2g	$91

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(+)-DIACETYL-L-TARTARIC ANHYDRIDE Properties

Melting point	130-135 °C(lit.)
Boiling point	316.55°C (rough estimate)
Density	1.5197 (rough estimate)
refractive index	90 ° (C=0.5, CHCl3)
storage temp.	2-8°C
solubility	Acetone, Chloroform (Slightly, Heated)
form	Crystals or Needles
color	White
optical activity	[α]20/D +59°, c = 6 in acetone
Water Solubility	Soluble in methanol and dichloromethane. Slightly soluble in water.
Sensitive	Moisture Sensitive
BRN	87315
InChI	1S/C8H8O7/c1-3(9)13-5-6(14-4(2)10)8(12)15-7(5)11/h5-6H,1-2H3/t5-,6-/m1/s1
InChIKey	XAKITKDHDMPGPW-PHDIDXHHSA-N
SMILES	CC(=O)O[C@@H]1[C@@H](OC(C)=O)C(=O)OC1=O
CAS DataBase Reference	6283-74-5(CAS DataBase Reference)
FDA UNII	D7XNF76O0K
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

3-10-21

HS Code

29321900

Storage Class

11 - Combustible Solids

REACH Registrations

Active

NFPA 704

	1
2		0

(+)-DIACETYL-L-TARTARIC ANHYDRIDE price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	358924	(+)-O,O′-Diacetyl-L-tartaric anhydride 97%	6283-74-5	50g	$217	2026-04-30	Buy
TCI Chemical	D1911	(+)-Diacetyl-L-tartaric Anhydride >97.0%(T)	6283-74-5	25g	$52	2026-04-30	Buy
Usbiological	D3441-60A	Di-O-acetyl-L-tartaric Anhydride	6283-74-5	500mg	$319	2026-06-03	Buy
TRC	TRC-D400570-500MG	Di-O-acetyl-L-tartaric Anhydride	6283-74-5	500mg	$72	2026-06-03	Buy
TRC	TRC-D400570-2G	Di-O-acetyl-L-tartaric Anhydride	6283-74-5	2g	$91	2026-06-03	Buy

Product number	Packaging	Price	Buy
358924	50g	$217	Buy
D1911	25g	$52	Buy
D3441-60A	500mg	$319	Buy
TRC-D400570-500MG	500mg	$72	Buy
TRC-D400570-2G	2g	$91	Buy

(+)-DIACETYL-L-TARTARIC ANHYDRIDE Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

Di-O-acetyl-L-tartaric Anhydride (cas# 6283-74-5) is a compound useful in organic synthesis.

Uses

(+)-O,O′-Diacetyl-L-tartaric anhydride may be used as a chiral derivatizating agent in the following:

determination of enantiomeric vigabatrin in mouse serum samples using ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UHPLC-Q-TOF-M)
determination of trantinterol in rat plasma by ultra performance liquid chromatography–electrospray ionization mass spectrometry (UPLC–MS/MS)

General Description

(+)-O,O′-Diacetyl-L-tartaric anhydride is an HPLC derivatization reagent for UV/Vis detection. It is mainly employed as a reagent for the chiral derivatization of amino alcohols. It also reacts with alkanoamines in aprotic medium containing trichloroacetic acid and produces tartaric acid monoesters.

Purification Methods

If the IR is good, i.e. no OH bands, then keep it in a vacuum desiccator overnight (over P2O5/paraffin) before use. If OH bands are present then reflux 4g in Ac2O (12.6mL) containing a few drops of conc H2SO4 for 10minutes (use a relatively large flask), pour onto ice, collect the crystals, wash with dry *C6H6 (2 x 2mL), stir with 17mL of cold Et2O, filter and dry in it a vacuum desiccator as above, or store it in dark evacuated ampoules under N2 in small aliquots. It is not very stable in air, the melting point of the crystals drop one degree in the first four days then remains constant (132-134o). If placed in a stoppered bottle, it becomes gummy and the m falls 100o in three days. Recrystllisation leads to decomposition. If good quality anhydride is required it, should be prepared freshly from tartaric acid. It sublimes in a CO2 atmosphere. [Shriner & Furrow Org Synth Coll Vol IV 242 1963, Bell Aust J Chem 34 671 1981, Beilstein 18 III/IV 2296.]

(+)-DIACETYL-L-TARTARIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(R,R)-Tartaric Acid Monomethyl Ester Diacetate

(+)-DIACETYL-L-TARTARIC ANHYDRIDE Suppliers

Global( 144)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
Shanghai UCHEM Inc.	+86-18930848214 +86-021-56762820	sales@myuchem.com	China	8899	58
ANHUI WITOP BIOTECH CO., LTD	+8618071025641	eric@witopchemical.com	China	23506	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20000	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49860	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
Aladdin Scientific		tp@aladdinsci.com	United States	57473	58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.	+8618950047208	ellena@amitychem.com	China	43392	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shanghai UCHEM Inc.	58
ANHUI WITOP BIOTECH CO., LTD	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Alfa Chemistry	58
GIHI CHEMICALS CO.,LIMITED	58
HANGZHOU LEAP CHEM CO., LTD.	58
Aladdin Scientific	58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.	58

View Lastest Price from (+)-DIACETYL-L-TARTARIC ANHYDRIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-08-12	(+)-DIACETYL-L-TARTARIC ANHYDRIDE 6283-74-5	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
	2021-07-02	(+)-O,O′-Diacetyl-L-tartaric anhydride 6283-74-5	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

(+)-DIACETYL-L-TARTARIC ANHYDRIDE
6283-74-5
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

(+)-O,O′-Diacetyl-L-tartaric anhydride
6283-74-5
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

(+)-DIACETYL-L-TARTARIC ANHYDRIDE Spectrum

(+)-DIACETYL-L-TARTARIC ANHYDRIDE(6283-74-5)¹HNMR (+)-DIACETYL-L-TARTARIC ANHYDRIDE(6283-74-5)IR (+)-DIACETYL-L-TARTARIC ANHYDRIDE(6283-74-5)Raman

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(R,R)-DIACETYLTARTARIC ACID ANHYDRIDE DIACETYL-L-TARTARIC ANHYDRIDE (+)-DI-O-ACETYL-L-TARTARIC ACID ANHYDRIDE (+)-DI-O-ACETYL-L-TARTARIC ANHYDRIDE DI-O-ACETYL-L-TARTARIC ANHYDRIDE L-(+)-O,O'-DIACETYL-TARTARIC ACID ANHYDRIDE (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate (+)-DI-O-ACETYLTARTARIC ACID ANHYDRIDE L-(+)-3,4-DIACETOXYTETRAHYDROFURAN-2,5-DIONE (+)-O,Oμ-Diacetyl-L-tartaric anhydride (+)-2-O,3-O-Diacetyl-L-tartaric anhydride (2R,3R)-2,3-Diacetoxysuccinic anhydride (3R)-2,5-Dioxotetrahydrofuran-3α,4β-diol diacetate (3R)-3α,4β-Bis(acetyloxy)-3,4-dihydro-2,5-furandione (3R)-3α,4β-Diacetoxyoxolane-2,5-dione [3R,4R,(+)]-3,4-Di(acetyloxy)-3,4-dihydrofuran-2,5-dione (+)-Diacetyl-L-tartaric anhydride,97% (+)-DI-O-ACETYL-L-WEINSURE-ANHYDRID O,O-diacetyl tartaric acid anhydride (+)-Diacetyl-L-tartaric anhydride, 97% 25GR (2R,3R)-Di-O-acetyltartaric Acid Anhydride (3R,4R)-3,4-Bis(acetyloxy)dihydro-2,5-furandione (R,R)-2,3-Diacetoxy-1,4-butanedioic Anhydride NSC 7712 (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl diacetate 2,5-Furandione, 3,4-bis(acetyloxy)dihydro-, (3R,4R)- (+)-O,O'-Diacetyl-L-tartaric anhydride 97% (+)-Diacetyl-L-tartaricAnhydride> (+)-O,O'-Diacetyl-L-tartaric anhydride Di-O-Acetyl-L-tartaric anhydrideQ: What is Di-O-Acetyl-L-tartaric anhydride Q: What is the CAS Number of Di-O-Acetyl-L-tartaric anhydride Q: What is the storage condition of Di-O-Acetyl-L-tartaric anhydride (+)-Diacetyl-L-tartaric Anhydride (AOTH) (+)-DIACETYL-L-TARTARIC ANHYDRIDE (+)-O,O′-Diacetyl-L-tartaric anhydride DATA 6283-74-5 C8H8O7 for Resolution of Bases Optical Resolution Asymmetric Synthesis Chiral Resolution Reagents Chiral Resolving Reagents UV-VIS Chiral Reagents for Resolution of Bases Optical Resolution Synthetic Organic Chemistry