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1-Phenylpiperazine

1-Phenylpiperazine structure

CAS No.: 92-54-6

Chemical Name:: 1-Phenylpiperazine

Synonyms: 92-54-6;Phenylpiperazine;N-PHENYLPIPERAZINE;Vortioxetine impurity A;1-Fenylpiperazin;AKOS BBS-00003581;1-fenylpiperazine;1-PHENYLPIPERAINE;1-PHENYLPIPERAZINE;4-Phenylpiperazine

CBNumber:: CB2201009

Molecular Formula:: C10H14N2

Molecular Weight:: 162.23

MDL Number:: MFCD00005957

MOL File:: 92-54-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:00:00

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1-Phenylpiperazine Properties

Melting point	18.8 °C
Boiling point	286 °C(lit.)
Density	1.062 g/mL at 25 °C(lit.)
refractive index	n20/D 1.588(lit.)
Flash point	>230 °F
storage temp.	2-8°C
solubility	Insoluble
form	Liquid
pka	pK1:8.71(+1) (25°C,μ=0.1)
Specific Gravity	1.062 (20/4℃)
color	Clear colorless to yellow
Water Solubility	Insoluble
BRN	132157
InChI	1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2
InChIKey	YZTJYBJCZXZGCT-UHFFFAOYSA-N
SMILES	C1CN(CCN1)c2ccccc2
CAS DataBase Reference	92-54-6(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	J9225CBI7D
NIST Chemistry Reference	Piperazine, 1-phenyl-(92-54-6)
EPA Substance Registry System	Piperazine, 1-phenyl- (92-54-6)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS06

Signal word

Danger

Hazard statements

H301-H310-H314

Precautionary statements

P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P361+P364

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

T,C

Risk Statements

22-24-34-36/37/38-23/24/25

Safety Statements

26-36/37/39-45-28A

RIDADR

UN 2922 8/PG 2

WGK Germany

RTECS

TM2625000

Hazard Note

Toxic/Corrosive

TSCA

TSCA listed

HazardClass

6.1

PackingGroup

HS Code

29335995

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications

Acute Tox. 2 Dermal
Acute Tox. 3 Oral
Eye Dam. 1
Skin Corr. 1B

REACH Registrations

Active

NFPA 704

	1
4		0

1-Phenylpiperazine price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P30004	1-Phenylpiperazine 99%	92-54-6	25g	$68.4	2026-04-30	Buy
Sigma-Aldrich	Y0001033	Levodropropizine impurity B European Pharmacopoeia (EP) Reference Standard	92-54-6	50 mg	$167	2026-04-30	Buy
Sigma-Aldrich	P30004	1-Phenylpiperazine 99%	92-54-6	100g	$139	2026-04-30	Buy
TCI Chemical	P0980	1-Phenylpiperazine >98.0%(GC)	92-54-6	25g	$55	2026-04-30	Buy
TCI Chemical	P0980	1-Phenylpiperazine >98.0%(GC)	92-54-6	250g	$428	2021-12-16	Buy

Product number	Packaging	Price	Buy
P30004	25g	$68.4	Buy
Y0001033	50 mg	$167	Buy
P30004	100g	$139	Buy
P0980	25g	$55	Buy
P0980	250g	$428	Buy

1-Phenylpiperazine Chemical Properties, Uses, Production

Chemical Properties

clear colorless to yellow liquid

Uses

Levodropropizine impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Safety Profile

Poison by ingestion and skin contact. A skin and severe eye irritant. Mutation data reported. Combustible when exposed to heat or flame. It supports combustion and decomposes to yield toxic fumes of NOx. To fight fire, use water, foam, dry chemical. See also PIPERAZINE

1-Phenylpiperazine synthesis

Synthesis of 1-Phenylpiperazine from Piperazine and Chlorobenzene

1-Phenylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

Dropropizine 4-(4-Bromo-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 1-(4-Bromophenyl)piperazine naphthalen-1-yl(4-phenylpiperazin-1-yl)methanone 2-Methyl-2-(4-phenylpiperazino)propanenitrile

1-(2-phenoxyethyl)-4-phenyl-piperazine N-(4-Methylphenyl)-2-(4-phenylpiperazino)acetamide N-(3,5-dichlorophenyl)-2-(4-phenylpiperazin-1-yl)acetamide N-(4-Methoxyphenyl)-2-(4-phenylpiperazino)acetamide tert-Butyl 4-phenylpiperazine-1-carboxylate

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1-Phenylpiperazine Suppliers

Global Suppliers ( 481)

Supplier	Tel	Email	Country	ProdList	Advantage
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.	0513-82104991 18862997351	sales11@btcpharm.com	China	859	58
Ningbo jinuo chemical co., LTD	0574-87314919 057487319282	info@nbinno.com	China	7046	58
NINGBO INNO PHARMCHEM CO.,LTD.	15558396803	sales@nbinno.com	China	135	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
future industrial shanghai co., ltd	400-0066400 13621662912	sales@jonln.com	China	1989	65
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81

Supplier	Advantage
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.	58
Ningbo jinuo chemical co., LTD	58
NINGBO INNO PHARMCHEM CO.,LTD.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
INTATRADE GmbH	66
3B Pharmachem (Wuhan) International Co.,Ltd.	69
future industrial shanghai co., ltd	65
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81

View Latest Price from 1-Phenylpiperazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	1-Phenylpiperazine 92-54-6	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
2025-12-16	Levodropropizine EP Impurit B 92-54-6		10mg	95%+	100000	Moxin Chemicals
2024-06-11	1-Phenylpiperazine 92-54-6		1kg	99%	1 ton	Anhui Yiao New Material Technology Co., Ltd

1-Phenylpiperazine
92-54-6
$1.10
99.00%
Dideu Industries Group Limited

Levodropropizine EP Impurit B
92-54-6
95%+
Moxin Chemicals

1-Phenylpiperazine
92-54-6
$0.00
99%
Anhui Yiao New Material Technology Co., Ltd

1-Phenylpiperazine Spectrum

1-Phenylpiperazine(92-54-6)MS 1-Phenylpiperazine(92-54-6)¹HNMR 1-Phenylpiperazine(92-54-6)¹³CNMR 1-Phenylpiperazine(92-54-6)IR1 1-Phenylpiperazine(92-54-6)Raman

92-54-6 (1-Phenylpiperazine) Related Search:

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1-(2,3-Epoxypropyl)-2-methyl-5-nitroimidazole Posaconazole 1-Boc-4-(2-formylphenyl)piperazine Dapiprazole Phenylacetone

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TIMTEC-BB SBB003943 LABOTEST-BB LTBB000705 1-Fenylpiperazin AKOS BBS-00003581 1-PHENYLPIPERAZINE Levodropropizine EP Impurity B Levodropropizine ImpurityⅡ:l-phenylpiperazine 1-Phenylpiperazine 97 1-Phenylpiperazine98% Piperazine, 1-phenyl- n-phenyldiethylenediamine 1-Phenylpiperazine 97-98% 1-fenylpiperazine PHENYL PIPERAZINE BASE 1-PHENYLPIPERAINE 1-PHENYLNONAN-1-ONE N-Phenylpiperazine ,99% 4-Phenylpiperazine N-Phenylpiperazine ,98% 1-PhenyldiethylenediaMine 1-Phenylpiperazine 99% 1-Phenylpiperazine N-Phenylpiperazine 92-54-6 1-Phenylpiperazine≥ 98% (Assay) N-Phenylpiperazine for synthesis Vortioxetine impurity A N-Phenyl piperazine 1-Phenylpiperazine Vortioxetine Impurity 2 [N-phenylpiperazine Levodropropizine Impurity(1-Phenylpiperazine) Levodropropizine impurity B CRS 1-Phenylpiperazine> Levodropropizine EP Impurity B (N-Phenylpiperazine) 1-Phenylpiperazine ISO 9001：2015 REACH 1-Phenyl Piperazine ---S TIANFU-CHEM 92-54-6 1-Phenylpiperazine 1-PHENYLPIPERAZINE For Synthesis J-PhenyI Piperazine Levodropropizine Impurity Levodropropizine Impurity 2 (Levodropropizine EP Impurity B) Levodropropizine EP Impurit B 1-Phenylpiperazine, 99% Levodropropizine ImpurityⅡ:l-phenylpiperazine N-PHENYLPIPERAZINE Phenylpiperazine 92-54-6 Piperidines Piperazines Heterocyclic Building Blocks Building Blocks Bioactive Small Molecules Building Blocks C10 Cell Biology Chemical Synthesis Heterocyclic Building Blocks P API intermediates (intermediate of levodropropizine)