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Dipeptide-2

Dipeptide-2 structure

CAS No.: 24587-37-9

Chemical Name:: Dipeptide-2

Synonyms: eyeliss;VAL-TRP;VW;L-VALYL-L-TRYPTOPHAN;VW-2;NH2-VW-OH;L-Val-Trp;DIPEPTIDE-2;H-VAL-TRP-OH;N-valyltryptophan

CBNumber:: CB2227911

Molecular Formula:: C16H21N3O3

Molecular Weight:: 303.36

MDL Number:: MFCD00037947

MOL File:: 24587-37-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-20 23:19:27

Product description	Number	Pack Size	Price
H-Val-Trp-OH	FV111018	0.05g	$226.88
H-Val-Trp-OH	FV111018	0.1g	$363
H-Val-Trp-OH	FV111018	0.25g	$544.5
Dipeptide 2 ≥95%	CS-0065112	1g	$48
Dipeptide 2 ≥95%	CS-0065112	5g	$117
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Dipeptide-2 Properties

Boiling point	604.8±55.0 °C(Predicted)
Density	1.268±0.06 g/cm3(Predicted)
storage temp.	−20°C
pka	3.14±0.10(Predicted)
form	Solid
color	White to off-white
Sequence	Val-Trp
Cosmetics Ingredients Functions	SKIN CONDITIONING
InChI	InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1
InChIKey	LZDNBBYBDGBADK-KBPBESRZSA-N
SMILES	C(O)(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C(C)C)N
FDA UNII	3G64B4AFQN

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	3

Dipeptide-2 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FV111018	H-Val-Trp-OH	24587-37-9	0.05g	$226.88	2026-06-04	Buy
Biosynth	FV111018	H-Val-Trp-OH	24587-37-9	0.1g	$363	2026-06-04	Buy
Biosynth	FV111018	H-Val-Trp-OH	24587-37-9	0.25g	$544.5	2026-06-04	Buy
ChemScene	CS-0065112	Dipeptide 2 ≥95%	24587-37-9	1g	$48	2026-06-04	Buy
ChemScene	CS-0065112	Dipeptide 2 ≥95%	24587-37-9	5g	$117	2026-06-04	Buy

Product number	Packaging	Price	Buy
FV111018	0.05g	$226.88	Buy
FV111018	0.1g	$363	Buy
FV111018	0.25g	$544.5	Buy
CS-0065112	1g	$48	Buy
CS-0065112	5g	$117	Buy

Dipeptide-2 Chemical Properties,Uses,Production

Description

Dipeptide-2 is a tiny peptide with only two amino acids (amino acids are the building block of proteins, and peptides are a few amino acids attached together), Valine and Tryptophan. It's part of a 3 actives complex called Eyeliss (with HMC and Palmitoyl Tetrapeptide-7) that's supposed to fight under-eye bags.
The manufacturer claims that this dipeptide in Eyeliss can increase lymphatic circulation and the three actives together represent a "global approach to treating puffy eyes". The clinical study of the manufacturer with 20 people and 3% Eyeliss showed improvement after 56 days for 70% of the participants.

Chemical Properties

H-VAL-TRP-OH is a white or off-white lyophilized powder.

Uses

Dipeptide 2 (N-Valyltryptophan; Val-Trp) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient[1]. Dipeptide 2 is an angiotensin-converting Enzyme (ACE)[2].

Definition

ChEBI: Dipeptide-2 is a synthetic peptide used for skin care.

Mode of action

Dipeptide-2 is a potent angiotensin-converting enzyme (ACE) inhibitor, which reduces vasoconstriction of blood vessels around the eyes by inhibiting ACE activity and promotes blood circulation, thus improving periorbital edema and reducing dark circles.

References

[1] Zhang L, et al. Cosmeceuticals and peptides. Clin Dermatol. 2009;27(5):485-494. DOI:10.1016/j.clindermatol.2009.05.013
[2] Bicak B. Structural, spectroscopic, molecular docking, ADME, molecular dynamics studies of Val-Trp dipeptide. J Biomol Struct Dyn. 2023;41(23):13873-13890. DOI:10.1080/07391102.2023.2183041

Dipeptide-2 synthesis

Synthesis of Dipeptide-2 from Z-VAL-TRP-OH

Dipeptide-2 Preparation Products And Raw materials

Raw materials

Z-VAL-TRP-OH L-Tryptophan L-Valine

Preparation Products

Dipeptide-2 Suppliers

Global( 281)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu Youngshe Chemical Co., Ltd.	+86-18108235634	Cecilia@youngshechem.com	China	2345	58
Hantai Biomedical Group Co. LTD	+86-18819265912	id002@cnhantide.com	China	37	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
BJV BIOTECH LTD	+86-0755-23089946 +86-19006605307	bjvbiotech@163.com	China	67	58
Sichuan Hantongkuntai Biotechnology Co., LTD.	18981903347	Hantongkuntai@foxmail.com	China	235	58
Shanghai Yunao International Trade Co., Ltd	+86-17621705551	asdf@shanghaihg.cn	China	262	58
henan kanbei chemical co.,ltd	+undefined-86-1523780-4566 +86-15237804566	henankanbeichemical@163.com	China	509	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2452	58
HR Biotechnology Co.,Ltd	+86-1 +86-1	1	China	110	58
Sichuan HongRi Pharma-Tech Co.,Ltd	+86-15680023009	ni@enlaibio.com	China	1103	58

Supplier	Advantage
Chengdu Youngshe Chemical Co., Ltd.	58
Hantai Biomedical Group Co. LTD	58
HANGZHOU LEAP CHEM CO., LTD.	58
BJV BIOTECH LTD	58
Sichuan Hantongkuntai Biotechnology Co., LTD.	58
Shanghai Yunao International Trade Co., Ltd	58
henan kanbei chemical co.,ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
HR Biotechnology Co.,Ltd	58
Sichuan HongRi Pharma-Tech Co.,Ltd	58

Dipeptide-2: Cosmetic Applications and Biotechnological Synthesis
Dipeptide-2 is a gentle, vegan-friendly cosmetic peptide suitable for all skin types, it also enables efficient protein modifi....
May 1，2026

View Lastest Price from Dipeptide-2 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-10	Dipeptide-2 24587-37-9	$500.00	1kg	≥99.00%	1000000	Chengdu Shengnuo Biopharm Co.,Ltd
2026-08-09	H-VAL-TRP-OH 24587-37-9			99%	2000kgs	Chongqing Zhihe Biopharmaceutical Co., Ltd.
2026-08-09	H-VAL-TRP-OH 24587-37-9			99%	2000kgs	Chongqing Zhihe Biopharmaceutical Co., Ltd.

Dipeptide-2
24587-37-9
$500.00
≥99.00%
Chengdu Shengnuo Biopharm Co.,Ltd

H-VAL-TRP-OH
24587-37-9
99%
Chongqing Zhihe Biopharmaceutical Co., Ltd.

H-VAL-TRP-OH
24587-37-9
99%
Chongqing Zhihe Biopharmaceutical Co., Ltd.

Dipeptide-2 Spectrum

Dipeptide-2(24587-37-9)¹HNMR Dipeptide-2(24587-37-9)¹³CNMR

24587-37-9(Dipeptide-2)Related Search:

ALPHA-METHYL-L-TRYPTOPHAN H-VAL-PNA HCL L-Valine benzyl ester hydrochloride H-VAL-ILE-OH H-VAL-ALA-OH

ALPHA-METHYL-L-VALINE HYDROCHLORIDE H-VAL-VAL-OH A-METHYL-L-TRYPTOPHAN L-VALINE TERT-BUTYL ESTER HYDROCHLORIDE L-Valine methyl ester hydrochloride

L-Valine benzyl ester 4-toluenesulfonate ALPHA-METHYL-DL-HISTIDINE DIHYDROCHLORIDE H-α-Me-Tyr(tBu)-OH H-VAL-TYR-OH H-VAL-NH2 HCL

H-ALPHA-ME-D-VAL-OH Endothelin-1 (human, porcine) Dipeptide-2

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H-VAL-TRP-OH L-Valyl-L-tyrosine Dipeptide Val-Try VW-2 Dipeptide-2 / Dipeptide Val-Try N-valyltryptophan Dipeptide-2\/VW-2\/H-VAL-TRP-OH Dipeptide-2,Eyeliss Dipeptide Diaminobutyroyl Benzylamide/Syn Ake (2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-(1H-indol-3-yl)propanoic acid Dipeptide-2 Dipeptide 2 L-Tryptophan, L-valyl- Cosmetic Peptide Dipeptide-2 powder H-VAL-TRP-OH USP/EP/BP Eye Care and Hair Growth Series Cosmetic Peptide Dipeptide-2 CAS 24587-37-9 (S)-2-((S)-2-Amino-3-methylbutanamido)-3-(1H-indol-3-yl)propanoic acid NH2-VW-OH Dipeptide /Genowhite L-Val-Trp N Valyltryptophan,NValyltryptophan (2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-(1H-indol-3-yl)propanoic acid DIPEPTIDE-2 L-VALYL-L-TRYPTOPHAN eyeliss VAL-TRP VW 24587-37-9 3061-94-4 Amino Acid Derivatives