Molsidomine
- CAS No.
- 25717-80-0
- Chemical Name:
- Molsidomine
- Synonyms
- SIN-10;Coruno;morial;CAS 276;CORVATON;corvasal;Corraton;MOTAZOMIN;SydnopharM;molsidolat
- CBNumber:
- CB2234645
- Molecular Formula:
- C9H14N4O4
- Molecular Weight:
- 242.23
- MDL Number:
- MFCD00869301
- MOL File:
- 25717-80-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 140-141°C |
|---|---|
| Boiling point | 385.05°C (rough estimate) |
| Density | 1.3186 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Sparingly soluble in water, soluble in anhydrous ethanol and in methylene chloride. |
| pka | pK (100°) 3.0 ± 0.1 |
| form | Solid |
| color | White to Off-White |
| λmax | 317nm(MeOH)(lit.) |
| Merck | 14,6234 |
| Major Application | pharmaceutical (small molecule) |
| InChI | InChI=1S/C9H14N4O4/c1-2-16-9(14)10-8-7-13(11-17-8)12-3-5-15-6-4-12/h7H,2-6H2,1H3/b10-8- |
| InChIKey | XLFWDASMENKTKL-NTMALXAHSA-N |
| SMILES | [N+]1([N-]O/C(=N\C(=O)OCC)/C=1)N1CCOCC1 |
| CAS DataBase Reference | 25717-80-0(CAS DataBase Reference) |
| FDA UNII | D46583G77X |
| ATC code | C01DX12 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | WU7677400 | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 780, 750, 1380, 1350 s.c.; 860, 800, 830, 760 i.v.; 700, 760, 1250, 1250 i.p.; 830, 840, 1050, 1200 orally (Nakaguchi) | |||||||||
| NFPA 704 |
|
Molsidomine price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000821 | Molsidomine European Pharmacopoeia (EP) Reference Standard | 25717-80-0 | 5 mg | $170 | 2026-04-30 | Buy |
| Sigma-Aldrich | M2901 | Molsidomine | 25717-80-0 | 500mg | $91.1 | 2023-01-07 | Buy |
| Sigma-Aldrich | M2901 | Molsidomine | 25717-80-0 | 5g | $522 | 2023-01-07 | Buy |
| TCI Chemical | M2524 | Molsidomine >98.0%(HPLC)(T) | 25717-80-0 | 1g | $43 | 2026-04-30 | Buy |
| TCI Chemical | M2524 | Molsidomine >98.0%(HPLC)(T) | 25717-80-0 | 5g | $127 | 2026-04-30 | Buy |
Molsidomine Chemical Properties, Uses, Production
Chemical Properties
White to Off-White Solid
Originator
Corvasal,Hoechst
Uses
Molsidomine is an antianginal agent. Molsidomine is an effective therapeutic agents in the treatment of angina pectoris. Molsidomine is a sydnonimine derivative that acts as a heterocyclic direct nitric oxide donor.
Definition
ChEBI: 1-ethoxy-N-[3-(4-morpholinyl)-5-oxadiazol-3-iumyl]methanimidate is a member of morpholines.
Manufacturing Process
1.6 parts by volume of ethyl chloroformate is stirred dropwise into a suspension of 1.0 part by weight of 3-morpholinosydnonimine hydrochloride in 5 parts by volume of pyridine, and the mixture is agitated for a while to allow reaction to take place. Pyridine is removed from the reaction mixture by evaporation, and the residue is dissolved in a small amount of water and extracted with chloroform several times. The extract is dehydrated by adding anhydrous magnesium sulfate and subjected to filtration. Chloroform is removed from the filtrate by distillation, crude crystals being obtained. Recrystallization of the crude crystals from toluene gives 0.6 part by weight of 3-morpholino-N-carboethoxysydnonimine having a melting point of 140°- 141°C. Yield 51%.
brand name
Corvaton (Hoechst-Roussel).
Therapeutic Function
Coronary vasodilator
Molsidomine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JIANGSU BAOSHENG LONGCHENG PHARMACUTICAL CO.,LTD | -- | sales@bslcpharm.com | China | 4 | 60 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
View Latest Price from Molsidomine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | Molsidomine
25717-80-0
|
$13.00-300.00 | 1KG | 99% | 20000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-05-11 | Molsidomine
25717-80-0
|
$30.00 | 99.98% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-22 | Molsidomine
25717-80-0
|
$30.00 | 99.98% | 10g | TargetMol Chemicals Inc. |
-
- Molsidomine
25717-80-0
- $13.00-300.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Molsidomine
25717-80-0
- $30.00
- 99.98%
- TargetMol Chemicals Inc.
-
- Molsidomine
25717-80-0
- $30.00
- 99.98%
- TargetMol Chemicals Inc.
